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Cosmetic ingredients

Nonivamide

Also known as N-Vanillylnonanamide, Pseudocapsaicin, Pelargonic acid vanillylamide

CAS 2444-46-4Formula C17H27NO3Molar mass 293.41 g/molEC 219-484-1
GHS signal word: Danger. Pictograms: Corrosive, Acute toxicity (severe), Harmful or irritant, Serious health hazard 40 suppliers listed
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Nonivamide chemical structure, C17H27NO3, CAS 2444-46-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
2444-46-4
Formula
C17H27NO3
Molar mass
293.41 g/mol
EC number
219-484-1
HS code
292429
Category
Cosmetic ingredients

What is Nonivamide?

Plain description, key identifiers and synonyms

Nonivamide is a capsaicinoid that is the carboxamide resulting from the formal condensation of the amino group of 4-hydroxy-3-methoxybenzylamine with the carboxy group of nonanoic acid. It is the active ingredient in many pepper sprays. It has a role as a lachrymator. It is a member of phenols and a capsaicinoid.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
N-[(4-hydroxy-3-methoxyphenyl)methyl]nonanamide
CAS number
2444-46-4 CAS number cross-checked
EC number
219-484-1
Molecular formula
C17H27NO3
UNII
S846B891OR
MDL number
MFCD00017286
INCI name
HYDROXYMETHOXYBENZYL PELARGONAMIDE
InChIKey
RGOVYLWUIBMPGK-UHFFFAOYSA-N
InChI
InChI=1S/C17H27NO3/c1-3-4-5-6-7-8-9-17(20)18-13-14-10-11-15(19)16(12-14)21-2/h10-12,19H,3-9,13H2,1-2H3,(H,18,20)
SMILES (canonical and isomeric)
CCCCCCCCC(=O)NCC1=CC(=C(C=C1)O)OC

Synonyms

  • N-Vanillylnonanamide
  • Pseudocapsaicin
  • Pelargonic acid vanillylamide
  • N-Vanillylnonamide
  • N-Vanillylpelargonamide
  • N-(4-Hydroxy-3-methoxybenzyl)nonanamide
  • Nonanoic acid vanillylamide
  • N-Nonanoyl vanillylamide
  • Vanillyl pelargonic amide
  • Vanillyl-N-nonylamide
  • Nonylic acid vanillylamide
  • Pelargonyl vanillylamide
  • Hydroxymethoxybenzyl pelargonamide
  • N-[(4-hydroxy-3-methoxyphenyl)methyl]nonanamide
  • Nonivamida
  • Nonanamide, N-[(4-hydroxy-3-methoxyphenyl)methyl]-
  • Nonanoyl vanillylamide
  • Nonivamidum
  • Hansaplast
  • vanillylnonanamide
  • Nonanoyl 4-hydroxy-3-methoxybenzylamide
  • PAVA
  • Nonylic acid vanillyamide
  • N-((4-Hydroxy-3-methoxyphenyl)methyl)nonanamide
  • Nonanamide, N-((4-hydroxy-3-methoxyphenyl)methyl)-
Show all 37 synonyms
  • vanillylnonamide
  • PGA vanillylamide
  • Vanillyl n-nonoylamide
  • Nonanamide, N-vanillyl-
  • desmethyldihydrocapsaicin
  • N-Vanillylnonanoamide
  • Capsaicin (Synthetic)
  • N-Nonylvanylamide
  • Capsaicin synthetic
  • N-((Hydroxy-3-methoxyphenyl)methyl)4-nonanamide
  • N-vanillyl nonanamide
  • N-Pelargonic Acid Vanillylamide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
293.41 g/molcalc.
Exact mass
293.1991 Dacalc.
LogP (octanol/water)
3.77calc.
Topological polar surface area
58.56 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
10calc.
Heavy atoms
21calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.59calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS05: Corrosive
Corrosive
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H301Toxic if swallowed.
  • H315Causes skin irritation.
  • H317May cause an allergic skin reaction.
  • H318Causes serious eye damage.
  • H319Causes serious eye irritation.
  • H334May cause allergy or asthma symptoms or breathing difficulties if inhaled.
  • H335May cause respiratory irritation.
Precautionary statements (28)
  • P233Keep container tightly closed.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P284In case of inadequate ventilation wear respiratory protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P317Get medical help.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P342 + P316If experiencing respiratory symptoms: Get emergency medical help immediately.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403Store in a well-ventilated place.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Nonivamide suppliers

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All 40 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

40 suppliers in 7 countries

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Nonivamide price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Cosmetics, Pharmaceuticals.

Cosmetic ingredient, INCI name HYDROXYMETHOXYBENZYL PELARGONAMIDE(fragrance)

Pharmacological actions

  • Sensory System Agents

Roles

  • analgesic
  • biophysical role
  • lachrymator
  • pharmaceutical

Functional uses

  • Deodorizer
  • Flavouring and nutrient
  • Fragrance

Cosmetic functions

  • Fragrance

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Nonivamide is traded under.

HS 2924.29Indicative HS code

Cyclic amides (including cyclic carbamates) and their derivatives, salts thereof, other

World exports in 2024
$5.69B
−5.1% vs 2023, imports $5.8B
2019 to 2024
Top exporters
  1. China32.3%
  2. Switzerland * partner reported13.6%
  3. Norway * partner reported12.8%
Top importers
  1. United States15.9%
  2. Ireland15.8%
  3. Germany11.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Nonivamide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Nonivamide, based on the data on this page

What is Nonivamide?

Nonivamide is a capsaicinoid that is the carboxamide resulting from the formal condensation of the amino group of 4-hydroxy-3-methoxybenzylamine with the carboxy group of nonanoic acid. It is the active ingredient in many pepper sprays. It has a role as a lachrymator. It is a member of phenols and a capsaicinoid.

What is the CAS number of Nonivamide?

The CAS registry number of Nonivamide is 2444-46-4.

What is the molecular formula and weight of Nonivamide?

The molecular formula of Nonivamide is C17H27NO3 and its molar mass is 293.41 g/mol.

What is Nonivamide used for?

Use classes: Cosmetics, Pharmaceuticals.

Is Nonivamide hazardous?

Nonivamide carries the GHS signal word "Danger". Main hazards: toxic if swallowed, causes skin irritation, may cause an allergic skin reaction. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Nonivamide?

Nonivamide is usually classified under HS code 292429 (Cyclic amides (including cyclic carbamates) and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Nonivamide?

CompoundList lists 40 suppliers of Nonivamide in China, United States, Switzerland, Germany and 3 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Nonivamide?

Suppliers quote Nonivamide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Nonivamide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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