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Skin conditioning agents and actives

Osthol

Also known as Osthole, Ostole, Ostol

CAS 484-12-8Formula C15H16O3Molar mass 244.29 g/molEC 610-421-7
71 suppliers listed
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Osthol chemical structure, C15H16O3, CAS 484-12-8
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Colorless needle like crystals
Melting point
83 to 84
Solubility
In water, 12.0 mg/L at 30 °C
HS code
293220
Category
Skin conditioning agents and actives
Illustrative photo, colourless crystals beside an amber glass bottle on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Osthol?

Plain description, key identifiers and synonyms

Osthole is a natural product found in Peucedanum ostruthium and Angelica pubescens. It has a role as a metabolite. It is a member of coumarins and a botanical anti-fungal agent.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one
CAS number
484-12-8 CAS number cross-checkedOther or deprecated CAS: 1440642-68-1
EC number
610-421-7
Molecular formula
C15H16O3
UNII
XH1TI1759C
MDL number
MFCD00076049
INCI name
OSTHOLE
InChIKey
MBRLOUHOWLUMFF-UHFFFAOYSA-N
InChI
InChI=1S/C15H16O3/c1-10(2)4-7-12-13(17-3)8-5-11-6-9-14(16)18-15(11)12/h4-6,8-9H,7H2,1-3H3
SMILES (canonical and isomeric)
CC(=CCC1=C(C=CC2=C1OC(=O)C=C2)OC)C

Synonyms

  • Osthole
  • Ostole
  • Ostol
  • 7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one
  • 2H-1-Benzopyran-2-one, 7-methoxy-8-(3-methyl-2-butenyl)-
  • 7-Methoxy-8-isopentenylcoumarin
  • 8-(3-Methyl-2-butenyl)herniarin
  • 7-Methoxy-8-(3-methyl-2-butenyl)-coumarin
  • 7-Methoxy-8-(3-methylbut-2-enyl)-2-chromenone
  • 7-methoxy-8-(3-methylpent-2-enyl)coumarin
  • 7-methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one
  • 7-methoxy-8-(3-methyl-2-buten-1-yl)-2H-chromen-2-one
  • 7-methoxy-8-(3-methyl-2-butenyl)coumarin
  • Coumarin, 7-methoxy-8-(3-methyl-2-butenyl)-
  • Osthole CRS
  • 7-Methoxy-8-(3-methyl-but-2-enyl)-chromen-2-one
  • Osthole (Standard)
  • 7-methoxy-8-(3-methyl-2-butenyl)-2h-1-benzopyran-2-one
  • 7-Methoxy-8-prenylcoumarin
  • Osthole, analytical standard
  • DivK1c_007042
  • ACon1_002155
  • Sdccgmls-0066780.p001
  • Osthole, primary pharmaceutical reference standard
  • 7-Methoxy-8-(3-methyl-2-butenyl)-2H-chromen-2-one #
Show all 29 synonyms
  • Osthole, European Pharmacopoeia (EP) Reference Standard
  • 7-methoxy-8-(3'-methyl-2'-butenyl)-2H-1-benzopyran-2-one
  • 7-Methoxy-8-(3-methyl-2-buten-1-yl)-2H-1-benzopyran-2-one
  • 7-Methoxy-8-(3-methylbut-2-en-1-yl)-2H-1-benzopyran-2-one

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Colorless needle like crystalsexp.
Melting point
83 to 84exp.
Solubility
In water, 12.0 mg/L at 30 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
244.29 g/molcalc.
Exact mass
244.1099 Dacalc.
LogP (octanol/water)
3.31calc.
Topological polar surface area
39.44 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
3calc.
Heavy atoms
18calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.27calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=c1ccc2ccccc2o1

O=c1ccc2ccccc2o1

2 rings, 11 atoms, the Coumarin ring system.

3,845 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS classification
Hazard pictograms

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Osthol suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 71 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

71 suppliers in 11 countries

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Osthol price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Traditional medicine (ingredient).

Cosmetic ingredient, INCI name OSTHOLE(skin conditioning)

Pharmacological actions

  • Adjuvants, Immunologic
  • Calcium Channel Blockers

Roles

  • metabolite

Functional uses

  • Softener and conditioner

Cosmetic functions

  • Skin conditioning

How it is made

From rhizome of Peucedanum ostruthium (L.) Koch (Imperatoria ostruthium L.) Umbelliferae, ... from Prangos pabularia Lindl., Umbelliferae.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Osthol is traded under.

HS 2932.20Indicative HS code

Lactones

World exports in 2024
$1.97B
−4.7% vs 2023, imports $2.07B
2019 to 2024
Top exporters
  1. China56.3%
  2. India * partner reported7.4%
  3. Germany7.3%
Top importers
  1. United States14.2%
  2. India * partner reported13.5%
  3. Brazil8.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Osthol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Osthol, based on the data on this page

What is Osthol?

Osthole is a natural product found in Peucedanum ostruthium and Angelica pubescens. It has a role as a metabolite. It is a member of coumarins and a botanical anti-fungal agent.

What is the CAS number of Osthol?

The CAS registry number of Osthol is 484-12-8. Other or deprecated CAS numbers: 1440642-68-1.

What is the molecular formula and weight of Osthol?

The molecular formula of Osthol is C15H16O3 and its molar mass is 244.29 g/mol.

What is Osthol used for?

Traditional medicine (ingredient).

Is Osthol hazardous?

No GHS hazard classification for Osthol is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Osthol?

Osthol is usually classified under HS code 293220 (Lactones). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Osthol?

CompoundList lists 71 suppliers of Osthol in China, United States, Germany, United Kingdom and 7 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Osthol in India?

1 supplier in India list Osthol on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Osthol?

Suppliers quote Osthol on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Osthol

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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