CompoundList
Sign in
Central nervous system drugs

Phentermine

Also known as Duromine, Ionamin, Lipopill

CAS 122-09-8Formula C10H15NMolar mass 149.24 g/molEC 204-522-1
GHS signal word: Danger. Pictograms: Acute toxicity (severe) Prohibited, not for trade Drug substance
Why it is not for trade
Phentermine chemical structure, C10H15N, CAS 122-09-8
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Oily liquid
Melting point
198 °C
Boiling point
205 °C
Solubility
SOL IN CHLOROFORM, ETHER, ACETONE & DIL ACIDS, SLIGHTLY SOL IN WATER
HS code
292146
Category
Central nervous system drugs
UN number
UN 1851

What is Phentermine?

Plain description, key identifiers and synonyms

Phentermine is a primary amine. It has a role as a central nervous system stimulant, a central nervous system drug, a sympathomimetic agent, an adrenergic agent, a dopaminergic agent and an appetite depressant. It is a conjugate base of a phentermine(1+).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-methyl-1-phenylpropan-2-amine
CAS number
122-09-8 CAS number cross-checkedOther or deprecated CAS: 1246819-25-9, 9008-94-0
EC number
204-522-1
Molecular formula
C10H15N
UNII
C045TQL4WP
InChIKey
DHHVAGZRUROJKS-UHFFFAOYSA-N
InChI
InChI=1S/C10H15N/c1-10(2,11)8-9-6-4-3-5-7-9/h3-7H,8,11H2,1-2H3
SMILES (canonical and isomeric)
CC(C)(CC1=CC=CC=C1)N

Synonyms

  • Duromine
  • Ionamin
  • Lipopill
  • Mirapront
  • 2-methyl-1-phenylpropan-2-amine
  • Normephentermine
  • alpha,alpha-Dimethylphenethylamine
  • Fentermina
  • Lonamin
  • Omnibex
  • Linyl
  • 1,1-Dimethyl-2-phenylethylamine
  • Phenterminum
  • Obermine
  • Phentrol
  • Phentrol 2
  • Phentrol 3
  • Phentrol 4
  • 2-Phenyl-tert-butylamine
  • Phenyl-tert-butylamine
  • alpha-Benzylisopropylamine
  • Qsiva
  • alpha,alpha-Dimethylbenzeneethanamine
  • 2-Amino-2-methyl-1-phenylpropane
  • Benzeneethanamine, alpha,alpha-dimethyl-
Show all 37 synonyms
  • alpha,alpha-Dimethyl-beta-phenylethylamine
  • Ethanamine, 1,1-dimethyl-2-phenyl-
  • Phenethylamine, alpha,alpha-dimethyl-
  • Qsymia component phentermine
  • AdipexP
  • Adipex P
  • Hydrochloride, Phentermine
  • MG 18370
  • Adipex-P
  • Phentermine resin
  • Phentermine-d5
  • DEA No. 1640

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Oily liquidexp.
Odour
CHARACTERISTIC OF AMINESexp.
Melting point
198 °Cexp.
Boiling point
205 °Cexp.
Solubility
SOL IN CHLOROFORM, ETHER, ACETONE & DIL ACIDS, SLIGHTLY SOL IN WATERexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
149.24 g/molcalc.
Exact mass
149.1204 Dacalc.
LogP (octanol/water)
1.97calc.
Topological polar surface area
26.02 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
2calc.
Heavy atoms
11calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.4calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)

Hazard statements

  • H301Toxic if swallowed.
Precautionary statements (7)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 1851

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Phentermine suppliers

Trading restrictions apply to this substance

Psychotropic substance

Phentermine is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: UN Convention on Psychotropic Substances 1971, HS 2022 subheading 2921.46 (amfetamine and related stimulants)

Our policy on controlled substances

Phentermine price

Indicative price range per kg from live supplier offers

Prices are not shown for prohibited substances.

Uses and applications

What the substance is used for, by industry and function

Appetite suppressant for the short-term (a few weeks) management of obesity.

Therapeutic category: Anorectic agent.

Use classes: Pharmaceuticals.

Industries and functions

Pharmacological actions

  • Adrenergic Agents
  • Appetite Depressants
  • Central Nervous System Stimulants
  • Sympathomimetics

Roles

  • adrenergic agent
  • anti-obesity agent
  • appetite depressant
  • appetite regulator
  • central nervous system drug
  • central nervous system stimulant
  • dopaminergic agent
  • hypoglycemic agent
  • neurotransmitter agent
  • pharmaceutical
  • protective agent
  • renoprotective agent
  • sympathomimetic agent

Functional uses

  • Pharmaceutical

Pharmacology

Phentermine is a Sympathomimetic Amine Anorectic. The physiologic effect of phentermine is by means of Appetite Suppression and Increased Sympathetic Activity.

How it is made

Preperation: Shelton, Van Campen, US 2590079 (1952 to Wyeth)

Prepartion: ... Abell et al., US 2408345 (1946 to Wm. S. Merrell)

Grignardization of benzyl alcohol with acetone, reacting the resulting alpha, alpha-dimethylpenethyl alcohol with sodium cyanide in acid to form the corresponding 2-formamido compound, and hydrolyzing this to phentermine.

Regulatory status

Inventories, regulations and trade controls that list this substance

Psychotropic substance

Phentermine is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: UN Convention on Psychotropic Substances 1971, HS 2022 subheading 2921.46 (amfetamine and related stimulants)

Our policy on controlled substances

Controls

  • US DEA controlled substance or listed chemical
  • Controlled psychotropic substance

Health and food

  • Active ingredient in FDA approved drug labels

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Phentermine is traded under.

HS 2921.46Exact HS code

Amfetamine (INN), benzfetamine (INN), dexamfetamine (INN), etilamfetamine (INN)…

World exports in 2024
$17.7M
−13.9% vs 2023, imports $15.8M
2019 to 2024
Top exporters
  1. Germany37.3%
  2. United States27.5%
  3. Denmark25.4%
Top importers
  1. United States26.3%
  2. Germany18.0%
  3. Australia16.2%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Phentermine is indicative (it was matched by name in the HS nomenclature). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Phentermine, based on the data on this page

What is Phentermine?

Phentermine is a primary amine. It has a role as a central nervous system stimulant, a central nervous system drug, a sympathomimetic agent, an adrenergic agent, a dopaminergic agent and an appetite depressant. It is a conjugate base of a phentermine(1+).

What is the CAS number of Phentermine?

The CAS registry number of Phentermine is 122-09-8. Other or deprecated CAS numbers: 1246819-25-9, 9008-94-0.

What is the molecular formula and weight of Phentermine?

The molecular formula of Phentermine is C10H15N and its molar mass is 149.24 g/mol.

What is Phentermine used for?

Appetite suppressant for the short-term (a few weeks) management of obesity. Therapeutic category: Anorectic agent. Use classes: Pharmaceuticals.

Is Phentermine hazardous?

Phentermine carries the GHS signal word "Danger". Main hazards: toxic if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Phentermine?

Phentermine is usually classified under HS code 292146 (Amfetamine (INN), benzfetamine (INN), dexamfetamine (INN), etilamfetamine (INN)…). This is indicative, confirm it with your customs broker before shipping.

Can I buy Phentermine on CompoundList?

No. Phentermine is on our prohibited list, so listings, quotes and messages for it are disabled. This page is kept for information only.

Guides for buyers

Practical guides that help when you source, ship or handle Phentermine

Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page

Explore more in Central nervous system drugs or HS code 292146

Not available for trade
Why