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Amines and amides

Chlorphentermine

Also known as Clorfentermina, Desopimon, Teramine

CAS 461-78-9Formula C10H14ClNMolar mass 183.68 g/molEC 207-314-9
GHS signal word: Warning. Pictograms: Harmful or irritant 10 suppliers listed
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Chlorphentermine chemical structure, C10H14ClN, CAS 461-78-9
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Liquid
Boiling point
100 to 102
Solubility
WHITE TO OFF-WHITE POWDER, ODORLESS & HAS BITTER TASTE, FREELY SOL IN WATER & ALC, SPARI…
HS code
292149
Category
Amines and amides
Illustrative photo, 200 litre steel drums of liquid in a chemical plant
Typical packagingIllustrative packaging image, not the actual product

What is Chlorphentermine?

Plain description, key identifiers and synonyms

Chlorphentermine is a member of amphetamines.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1-(4-chlorophenyl)-2-methylpropan-2-amine
CAS number
461-78-9 CAS number cross-checked
EC number
207-314-9
Molecular formula
C10H14ClN
UNII
NHW07912O7
MDL number
MFCD00055368
InChIKey
ZCKAMNXUHHNZLN-UHFFFAOYSA-N
InChI
InChI=1S/C10H14ClN/c1-10(2,12)7-8-3-5-9(11)6-4-8/h3-6H,7,12H2,1-2H3
SMILES (canonical and isomeric)
CC(C)(CC1=CC=C(C=C1)Cl)N

Synonyms

  • Clorfentermina
  • Desopimon
  • Teramine
  • Effox
  • Lucofen SA
  • Chlorphenterminum
  • 4-Chloro-alpha,alpha-dimethylphenethylamine
  • 1-(p-Chlorophenyl)-2-methyl-2-aminopropane
  • alpha,alpha-Dimethyl-p-chlorophenethylamine
  • p-Chloro-alpha,alpha-dimethylphenethylamine
  • 4-Chloro-alpha,alpha-dimethylbenzeneethanamine
  • beta-(p-Chlorophenyl)-alpha,alpha-dimethylethylamine
  • 1-(p-Chlorophenyl)-2-methyl-2-propylamine
  • Benzeneethanamine, 4-chloro-alpha,alpha-dimethyl-
  • Phenethylamine, p-chloro-alpha,alpha-dimethyl-
  • 1-(4-chlorophenyl)-2-methylpropan-2-amine
  • 2-(4-Chloro-phenyl)-1,1-dimethyl-ethylamine
  • DEA No. 1645
  • Chlorophentermine
  • Chlorphenteramine
  • Lucofen (Salt/Mix)
  • 1,1-dimethyl-2-(4-chlorophenyl)ethylamine
  • 4-12-00-02823 (Beilstein Handbook Reference)
  • a,a-Dimethyl-p-chlorophenethylamine
  • 4-Chloro-a,a-dimethylphenethylamine
Show all 27 synonyms
  • 4-Chloro-a,a-dimethylbenzeneethanamine
  • 1-(4-Chlorophenyl)-2-methyl-2-propanamine #

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Liquidexp.
Boiling point
100 to 102exp.
Solubility
WHITE TO OFF-WHITE POWDER, ODORLESS & HAS BITTER TASTE, FREELY SOL IN WATER & ALC, SPARINGLY SOL IN CHLOROFORM, PRACTICALLY INSOL IN ETHER /CHLORPHENTERMINE HYDROCHLORIDE/exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
183.68 g/molcalc.
Exact mass
183.0815 Dacalc.
LogP (octanol/water)
2.62calc.
Topological polar surface area
26.02 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
2calc.
Heavy atoms
12calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.4calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (19)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Chlorphentermine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 10 suppliers
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Where suppliers are based

10 suppliers in 7 countries

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Chlorphentermine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Pharmacological actions

  • Sympathomimetics

Pharmacology

Chlorphentermine is a chlorinated analogue of phentermine, a sympathomimetic amine with central nervous system (CNS) stimulating and anorexic activity. Chlorphentermine acts by facilitating the release of catecholamines, especially noradrenaline and dopamine, from nerve terminals in the brain and also inhibits their uptake. The increase in synaptic concentrations of these catecholamines causes behavioral changes including an increase in motor activity, mental alertness and excitement, causes euphoria, and suppresses appetite.

How it is made

P-chlorobenzyl chloride is grignardized with acetone, resulting 1-(p-chlorophenyl)-2-methyl-2-propanol ... Reacted with sodium cyanide in acetic acid-sulfuric acid environment to form corresponding 2-formamido compd & this ... Hydrolyzed with alkali to form chlorphentermine. Treatment with hydrogen chloride ... Yields hcl.

Regulatory status

Inventories, regulations and trade controls that list this substance

Controls

  • US DEA controlled substance or listed chemical

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Chlorphentermine is traded under.

HS 2921.49Indicative HS code

Aromatic monoamines and their derivatives, salts thereof, other

World exports in 2024
$1.14B
+5.6% vs 2023, imports $1.06B
2019 to 2024
Top exporters
  1. Germany23.3%
  2. China19.4%
  3. Singapore14.6%
Top importers
  1. Belgium15.9%
  2. South Korea15.0%
  3. Germany12.8%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Chlorphentermine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Chlorphentermine, based on the data on this page

What is Chlorphentermine?

Chlorphentermine is a member of amphetamines.

What is the CAS number of Chlorphentermine?

The CAS registry number of Chlorphentermine is 461-78-9.

What is the molecular formula and weight of Chlorphentermine?

The molecular formula of Chlorphentermine is C10H14ClN and its molar mass is 183.68 g/mol.

What is Chlorphentermine used for?

Use classes: Pharmaceuticals.

Is Chlorphentermine hazardous?

Chlorphentermine carries the GHS signal word "Warning". Main hazards: harmful if swallowed, causes skin irritation, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Chlorphentermine?

Chlorphentermine is usually classified under HS code 292149 (Aromatic monoamines and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Chlorphentermine?

CompoundList lists 10 suppliers of Chlorphentermine in United States, China, Canada, Germany and 3 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Chlorphentermine?

Suppliers quote Chlorphentermine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Chlorphentermine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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