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Picolinic acid

Also known as Pyridine-2-carboxylic acid, 2-Pyridinecarboxylic acid, 2-Carboxypyridine

Picolinic acid chemical structure, C6H5NO2, CAS 98-98-6
2D chemical structure

Key facts

What buyers check first

CAS number
98-98-6
Formula
C6H5NO2
Physical form
Solid
Melting point
136.5 ยฐC
HS code
293339
Category
Impurities and reference standards
Illustrative photo, 25 kg white woven sacks of powder on a pallet in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Picolinic acid?

Plain description, key identifiers and synonyms

Picolinic acid is a pyridinemonocarboxylic acid in which the carboxy group is located at position 2. It is an intermediate in the metabolism of tryptophan. It has a role as a MALDI matrix material and a human metabolite. It is a conjugate acid of a picolinate.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
pyridine-2-carboxylic acid
CAS number
98-98-6 CAS number cross-checkedOther or deprecated CAS: 32075-31-3, 88161-53-9
EC number
202-719-7
Molecular formula
C6H5NO2
UNII
QZV2W997JQ
MDL number
MFCD00006293
INCI name
PICOLINIC ACID
InChIKey
SIOXPEMLGUPBBT-UHFFFAOYSA-N
InChI
InChI=1S/C6H5NO2/c8-6(9)5-3-1-2-4-7-5/h1-4H,(H,8,9)
SMILES (canonical and isomeric)
C1=CC=NC(=C1)C(=O)O

Synonyms

  • Pyridine-2-carboxylic acid
  • 2-Pyridinecarboxylic acid
  • 2-Carboxypyridine
  • o-Pyridinecarboxylic acid
  • Acide picolique
  • alpha-Pyridinecarboxylic acid
  • 2-pyridine carboxylic acid
  • 2-Picolinic acid
  • alpha-Picolinic acid
  • Pyridinecarboxylic acid
  • Pyridine-carboxylique-2
  • Isoniazid Impurity G
  • Pyridinecarboxylic acid-(2)
  • PCL 016
  • pyridine, 2-carboxy-
  • Nicogamol
  • Nikogamol
  • 2-pyridinecarboxylate
  • Acidepicolique
  • picolinic-acid
  • picolic acid
  • 2-picolic acid
  • A-Picolinic acid
  • Isoniazid Impurity 9
  • pyridine carboxylic acid
Show all 34 synonyms
  • pyridine-carboxylic acid
  • 2-pyridincarboxylic acid
  • pyridinium 2-carboxylate
  • a-Pyridinecarboxylic acid
  • 2-pyridine carboxic acid
  • Pyridine-A-carboxylic acid
  • 2-pyridine-carboxylic Acid
  • 5-22-02-00003 (Beilstein Handbook Reference)
  • Picolinic acid (PCL 016)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Physical form
Solidexp.
Melting point
136.5 ยฐCexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
123.11 g/molcalc.
Exact mass
123.032 Dacalc.
LogP (octanol/water)
0.78calc.
Topological polar surface area
50.19 ร…ยฒcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
1calc.
Heavy atoms
9calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccncc1

c1ccncc1

1 ring, 6 atoms, the Pyridine ring system.

118,162 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS05: Corrosive
Corrosive
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
  • H315Causes skin irritation.
  • H318Causes serious eye damage.
  • H319Causes serious eye irritation.
  • H332Harmful if inhaled.
  • H335May cause respiratory irritation.
Precautionary statements (21)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P317Get medical help.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Picolinic acid suppliers

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Picolinic acid price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Cosmetic ingredient, INCI name PICOLINIC ACID(antioxidant, skin conditioning - miscellaneous)

Pharmacological actions

  • Iron Chelating Agents

Roles

  • MALDI matrix material
  • animal metabolite
  • eukaryotic metabolite
  • human metabolite
  • mammalian metabolite
  • metabolite

Cosmetic functions

  • Antioxidant
  • Skin conditioning - miscellaneous

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Picolinic acid is traded under.

HS 2933.39Indicative HS code

Heterocyclic compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structureโ€ฆ

World exports in 2024
$9.16B
โˆ’17.9% vs 2023, imports $10.6B
2019 to 2024
Top exporters
  1. China21.5%
  2. India * partner reported12.3%
  3. Ireland11.6%
Top importers
  1. Germany14.2%
  2. United States12.8%
  3. Brazil10.1%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Picolinic acid is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Picolinic acid, based on the data on this page

What is Picolinic acid?

Picolinic acid is a pyridinemonocarboxylic acid in which the carboxy group is located at position 2. It is an intermediate in the metabolism of tryptophan. It has a role as a MALDI matrix material and a human metabolite. It is a conjugate acid of a picolinate.

What is the CAS number of Picolinic acid?

The CAS registry number of Picolinic acid is 98-98-6. Other or deprecated CAS numbers: 32075-31-3, 88161-53-9.

What is the molecular formula and weight of Picolinic acid?

The molecular formula of Picolinic acid is C6H5NO2 and its molar mass is 123.11 g/mol.

What is Picolinic acid used for?

Known uses and roles of Picolinic acid include antioxidants in cosmetics and personal care, skin conditioning agents in cosmetics and personal care, maldi matrix material, animal metabolite, eukaryotic metabolite and 6 more.

Is Picolinic acid hazardous?

Picolinic acid carries the GHS signal word "Danger". Main hazards: harmful if swallowed, causes skin irritation, causes serious eye damage. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Picolinic acid?

Picolinic acid is usually classified under HS code 293339 (Compounds containing an unfused pyridine ring (whether or not hydrogenated) in theโ€ฆ). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Picolinic acid?

CompoundList lists 102 suppliers of Picolinic acid in China, United States, United Kingdom, Germany and 10 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Picolinic acid in India?

3 suppliers in India list Picolinic acid on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Picolinic acid?

Suppliers quote Picolinic acid on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Picolinic acid

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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