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Central nervous system drugs

Piribedil

Also known as Trivastal, 2-(4-Piperonyl-1-piperazinyl)pyrimidine, 2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine

CAS 3605-01-4Formula C16H18N4O2Molar mass 298.35 g/molEC 222-764-6
GHS signal word: Warning. Pictograms: Harmful or irritant, Serious health hazard 44 suppliers listed
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Piribedil chemical structure, C16H18N4O2, CAS 3605-01-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
3605-01-4
Formula
C16H18N4O2
Molar mass
298.35 g/mol
EC number
222-764-6
HS code
293499
Category
Central nervous system drugs

What is Piribedil?

Plain description, key identifiers and synonyms

2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]pyrimidine is a N-arylpiperazine.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine
CAS number
3605-01-4 CAS number cross-checked
EC number
222-764-6
Molecular formula
C16H18N4O2
UNII
DO22K1PRDJ
MDL number
MFCD00868264
InChIKey
OQDPVLVUJFGPGQ-UHFFFAOYSA-N
InChI
InChI=1S/C16H18N4O2/c1-4-17-16(18-5-1)20-8-6-19(7-9-20)11-13-2-3-14-15(10-13)22-12-21-14/h1-5,10H,6-9,11-12H2
SMILES (canonical and isomeric)
C1CN(CCN1CC2=CC3=C(C=C2)OCO3)C4=NC=CC=N4

Synonyms

  • Trivastal
  • 2-(4-Piperonyl-1-piperazinyl)pyrimidine
  • 2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine
  • EU 4200
  • ET 495
  • Piribedilum
  • Pyrimidine, 2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-
  • Piribendyl
  • Pyrimidine, 2-(4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl)-
  • 2-{4-[(2H-1,3-benzodioxol-5-yl)methyl]piperazin-1-yl}pyrimidine
  • 2-(4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl)pyrimidine
  • Trivastal lp
  • 2-(4-((2H-1,3-benzodioxol-5-yl)methyl)piperazin-1-yl)pyrimidine
  • Piribedil Mono hydrochloride
  • Mono-hydrochloride, Piribedil
  • Trivastan
  • 2-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)pyrimidine
  • 2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]pyrimidine
  • Biomol-NT_000044
  • 1-(2-Pyrimidyl)-4-piperonylpiperazine
  • Pyrimidine, 2-(4-piperonyl-1-piperazinyl)-
  • Piribedil (INN)
  • 2-(4-(3,4-Methylenedioxybenzyl)piperazino)pyrimidine
  • 1-(3,4-Methylenedioxybenzyl)-4-(2-pyrimidyl)piperazine
  • 2-(4-(1,3-Benzodioxol-5-ylmethyl)-1-piperazinyl)pyrimidine
Show all 32 synonyms
  • 1-(2-Pyrimidyl)-4-(3,4-methylenedioxybenzyl)piperazine
  • 2-(4-(Benzo[d][13]dioxol-5-ylmethyl)piperazin-1-yl)pyrimidine
  • 2-[4-(2H-1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine
  • Piribedile
  • Trivastal (TN)
  • Piribedil (Standard)
  • Tocris-1031

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
298.35 g/molcalc.
Exact mass
298.143 Dacalc.
LogP (octanol/water)
1.53calc.
Topological polar surface area
50.72 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
6calc.
Rotatable bonds
3calc.
Heavy atoms
22calc.
Rings
4calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.38calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1cnc(N2CCN(Cc3ccc4c(c3)OCO4)CC2)nc1

c1cnc(N2CCN(Cc3ccc4c(c3)OCO4)CC2)nc1

4 rings, 22 atoms. This chemical is the scaffold itself.

27 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H302Harmful if swallowed.
  • H336May cause drowsiness or dizziness.
  • H362May cause harm to breast-fed children.
  • H373May cause damage to organs through prolonged or repeated exposure.
  • H412Harmful to aquatic life with long lasting effects.
Precautionary statements (16)
  • P203Obtain, read and follow all safety instructions before use.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P263Avoid contact during pregnancy and while nursing.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P273Avoid release to the environment.
  • P301 + P317If swallowed: Get medical help.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P330Rinse mouth.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Piribedil suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 44 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

44 suppliers in 11 countries

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Piribedil price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Industries and functions

Pharmacological actions

  • Antiparkinson Agents
  • Dopamine Agonists

Roles

  • antidyskinesia agent
  • antiparkinson drug
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Piribedil is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Piribedil is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Piribedil, based on the data on this page

What is Piribedil?

2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]pyrimidine is a N-arylpiperazine.

What is the CAS number of Piribedil?

The CAS registry number of Piribedil is 3605-01-4.

What is the molecular formula and weight of Piribedil?

The molecular formula of Piribedil is C16H18N4O2 and its molar mass is 298.35 g/mol.

What is Piribedil used for?

Known uses and roles of Piribedil include cns agents in pharmaceuticals, antidyskinesia agent, antiparkinson drug, pharmaceutical, antiparkinson agents and 1 more.

Is Piribedil hazardous?

Piribedil carries the GHS signal word "Warning". Main hazards: harmful if swallowed, may cause drowsiness or dizziness, may cause harm to breast-fed children. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Piribedil?

Piribedil is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Piribedil?

CompoundList lists 44 suppliers of Piribedil in China, United States, United Kingdom, Hong Kong and 7 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Piribedil in India?

2 suppliers in India list Piribedil on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Piribedil?

Suppliers quote Piribedil on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Piribedil

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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