CompoundList

Pro-Met

Also known as L-Prolyl-L-methionine, L-Pro-L-Met, Prolyl-Methionine

CAS 52899-08-8Formula C10H18N2O3SMolar mass 246.33 g/mol
Pro-Met chemical structure, C10H18N2O3S, CAS 52899-08-8
2D chemical structure

Key facts

What buyers check first

CAS number
52899-08-8
Formula
C10H18N2O3S
Molar mass
246.33 g/mol
HS code
293399
Category
Peptides

What is Pro-Met?

Plain description, key identifiers and synonyms

Pro-Met is a dipeptide obtained by formal condensation of the carboxy group of L-proline with the amino group of L-methionine. It is functionally related to a L-methionine and a L-proline.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2S)-4-methylsulfanyl-2-[[(2S)-pyrrolidine-2-carbonyl]amino]butanoic acid
CAS number
52899-08-8 CAS number cross-checked
Molecular formula
C10H18N2O3S
MDL number
MFCD00057180
InChIKey
MTWJTFBVRDGROD-YUMQZZPRSA-N
InChI
InChI=1S/C10H18N2O3S/c1-16-6-4-8(10(14)15)12-9(13)7-3-2-5-11-7/h7-8,11H,2-6H2,1H3,(H,12,13)(H,14,15)/t7-,8-/m0/s1
Canonical SMILES
CSCCC(NC(=O)C1CCCN1)C(=O)O
Isomeric SMILES
CSCC[C@@H](C(=O)O)NC(=O)[C@@H]1CCCN1

Synonyms

  • L-Prolyl-L-methionine
  • L-Pro-L-Met
  • Prolyl-Methionine
  • (2S)-4-(methylthio)-2-{[(2S)-pyrrolidin-2-ylcarbonyl]amino}butanoic acid
  • Proline-Methionine dipeptide
  • (2S)-4-(methylthio)-2-(((2S)-pyrrolidin-2-ylcarbonyl)amino)butanoic acid
  • 2-((hydroxy(pyrrolidin-2-yl)methylidene)amino)-4-(methylsulfanyl)butanoate
  • 2-((hydroxy(pyrrolidin-2-yl)methylidene)amino)-4-(methylsulphanyl)butanoate
  • 2-{[hydroxy(pyrrolidin-2-yl)methylidene]amino}-4-(methylsulfanyl)butanoate
  • 2-{[hydroxy(pyrrolidin-2-yl)methylidene]amino}-4-(methylsulphanyl)butanoate
  • 2-((hydroxy(pyrrolidin-2-yl)methylidene)amino)-4-(methylsulphanyl)butanoic acid
  • 2-{[hydroxy(pyrrolidin-2-yl)methylidene]amino}-4-(methylsulphanyl)butanoic acid
  • H-PRO-MET-OH
  • (2S)-4-methylsulfanyl-2-[[(2S)-pyrrolidine-2-carbonyl]amino]butanoic acid
  • prolylmethionine
  • PM dipeptide
  • P-M Dipeptide
  • (S)-4-(Methylthio)-2-((S)-pyrrolidine-2-carboxamido)butanoic acid
  • Proline Methionine dipeptide
  • P-M

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
246.33 g/molcalc.
Exact mass
246.1038 Dacalc.
LogP (octanol/water)
0.06calc.
Topological polar surface area
78.43 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
6calc.
Heavy atoms
16calc.
Rings
1calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.8calc.
Formal charge
0calc.
Stereocentres
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1CCNC1

C1CCNC1

1 ring, 5 atoms, the Pyrrolidine ring system.

22,348 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Pro-Met suppliers

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Pro-Met price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Applications are not documented for this substance yet. Suppliers often describe uses on their product pages, linked in the suppliers list above.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Pro-Met is traded under.

HS 2933.99Indicative HS code

Heterocyclic compounds with nitrogen hetero-atom(s) only, other

World exports in 2024
$12.1B
−31.0% vs 2023, imports $28.8B
2019 to 2024
Top exporters
  1. China30.5%
  2. India * partner reported16.3%
  3. Ireland9.0%
Top importers
  1. Slovenia31.7%
  2. Italy24.2%
  3. United States5.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Pro-Met is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Pro-Met, based on the data on this page

What is Pro-Met?

Pro-Met is a dipeptide obtained by formal condensation of the carboxy group of L-proline with the amino group of L-methionine. It is functionally related to a L-methionine and a L-proline.

What is the CAS number of Pro-Met?

The CAS registry number of Pro-Met is 52899-08-8.

What is the molecular formula and weight of Pro-Met?

The molecular formula of Pro-Met is C10H18N2O3S and its molar mass is 246.33 g/mol.

Is Pro-Met hazardous?

No GHS hazard classification for Pro-Met is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Pro-Met?

Pro-Met is usually classified under HS code 293399 (Heterocyclic compounds with nitrogen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Pro-Met?

Post a free request on CompoundList and suppliers of Pro-Met will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Pro-Met?

Suppliers quote Pro-Met on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Pro-Met

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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