CompoundList
Sign in
Synthetic aroma chemicals

Propionic anhydride

Also known as Propanoic anhydride, Propanoic acid, anhydride, Propionic acid anhydride

CAS 123-62-6Formula C6H10O3Molar mass 130.14 g/molEC 204-638-2
GHS signal word: Danger. Pictograms: Corrosive 24 suppliers listed
Get quotes Compare 24 suppliers
Propionic anhydride chemical structure, C6H10O3, CAS 123-62-6
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Colorless liquid
Melting point
-45 °C
Boiling point
170 °C
Density
1.011 g/cm³ at 20 °C
Flash point
74 °C
HS code
291550
Category
Synthetic aroma chemicals
UN number
UN 2496
Illustrative photo, a 1000 litre IBC tote of clear liquid in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Propionic anhydride?

Plain description, key identifiers and synonyms

Propionic anhydride is a colorless liquid with a pungent odor. Flash point 165 °F. Density 8.4 lb /gal. Corrosive to metals and tissue.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
propanoyl propanoate
CAS number
123-62-6 CAS number cross-checked
EC number
204-638-2
Molecular formula
C6H10O3
UNII
E3A2VV18E6
MDL number
MFCD00009303
InChIKey
WYVAMUWZEOHJOQ-UHFFFAOYSA-N
InChI
InChI=1S/C6H10O3/c1-3-5(7)9-6(8)4-2/h3-4H2,1-2H3
SMILES (canonical and isomeric)
CCC(=O)OC(=O)CC

Synonyms

  • Propanoic anhydride
  • Propanoic acid, anhydride
  • Propionic acid anhydride
  • Propionyl oxide
  • Methylacetic anhydride
  • Anhydrid kyseliny propionove
  • propanoic acid anhydride
  • propanoyl propanoate
  • Propanoic acid, 1,1'-anhydride
  • proprionic anhydride
  • (EtCO)2O
  • Propionic anhydride, 97%
  • 4-02-00-00722 (Beilstein Handbook Reference)
  • Propionic anhydride, >=99%
  • Propanoic acid,anhydride
  • C2H5C(O)OC(O)C2H5
  • Propionic anhydride, pract
  • UN 2496
  • Propionic anhydride [UN2496] [Corrosive]
  • Propionic anhydride, purum, >=96.0% (NT)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Colorless liquidexp.
Odour
Very rancid odorexp.
Melting point
-45 °Cexp.
Boiling point
170 °Cexp.
Density
1.011 g/cm³ at 20 °Cexp.
Flash point
74 °Cexp.
Autoignition temperature
285 °Cexp.
Solubility
Decomposed by water, soluble in methanol, ethanol, ether and chloroformexp.
Vapour pressure
VP: 1 mm Hg at 20.6 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
130.14 g/molcalc.
Exact mass
130.063 Dacalc.
LogP (octanol/water)
0.88calc.
Topological polar surface area
43.37 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
2calc.
Heavy atoms
9calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.67calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS05: Corrosive
Corrosive
231NFPA 704 rating

Hazard statements

  • H314Causes severe skin burns and eye damage.
Precautionary statements (12)
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P330 + P331If swallowed: Rinse mouth. Do not induce vomiting.
  • P302 + P361 + P354If on skin: Take off immediately all contaminated clothing. Immediately rinse with water for several minutes.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P316Get emergency medical help immediately.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P363Wash contaminated clothing before reuse.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 2496
Transport hazard class
8
Packing group
III

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Propionic anhydride suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 24 suppliers
24 of 24 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

24 suppliers in 8 countries

Send one request to many suppliers

Choose up to 10 suppliers or let us match your request. Compare quotes side by side, free.

Choose suppliersPost a request

Propionic anhydride price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Esterifying agent for fats and oils, cellulose, dehydrating medium for nitrations and sulfonations, alkyd resins, dyestuffs, and pharmaceuticals.

Esterifying agent for perfume oils, fats, cellulose, alkylated resins, dyestuffs, drugs and as a dehydrating agent.

Propionic anhydride is used as an esterifying agent for fatty acids and cellulose, for the production of alkyd resins and perfume oils, and for the introduction of the propionyl group into dyes and pharmaceuticals.

How it is made

Propionic anhydride is produced industrially either by heating propionic acid at 8 bar to 235 °C and distilling off the water formed, or by heating propionic acid with propionyl chloride in an inert solvent to 160 °C. Other possible routes involve the reaction of ethylene, carbon monoxide, and propionic acid in the presence of nickel carbonyl (Reppe synthesis) or cobalt or nickel iodide.

Obtained by dehydration of the acid or by carbonylation of its esters, ... from propionaldehyde by air oxidation in the presence of cobalt & copper acetate catalysts, ... other synthesis (methods) ... from ethanol & carbon monoxide.

Regulatory status

Inventories, regulations and trade controls that list this substance

Europe

  • EU harmonised classification (CLP Annex VI)
    Index no: 607-010-00-X

Controls

  • US DEA controlled substance or listed chemical

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Propionic anhydride is traded under.

HS 2915.50Indicative HS code

Propionic acid, its salts and esters

World exports in 2024
$421M
+3.2% vs 2023, imports $422M
2019 to 2024
Top exporters
  1. United States26.5%
  2. China22.5%
  3. Netherlands14.6%
Top importers
  1. Netherlands15.2%
  2. India * partner reported7.6%
  3. United States7.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Propionic anhydride is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Propionic anhydride, based on the data on this page

What is Propionic anhydride?

Propionic anhydride is a colorless liquid with a pungent odor. Flash point 165 °F. Density 8.4 lb /gal. Corrosive to metals and tissue.

What is the CAS number of Propionic anhydride?

The CAS registry number of Propionic anhydride is 123-62-6.

What is the molecular formula and weight of Propionic anhydride?

The molecular formula of Propionic anhydride is C6H10O3 and its molar mass is 130.14 g/mol.

What is Propionic anhydride used for?

Esterifying agent for fats and oils, cellulose, dehydrating medium for nitrations and sulfonations, alkyd resins, dyestuffs, and pharmaceuticals. Esterifying agent for perfume oils, fats, cellulose, alkylated resins, dyestuffs, drugs and as a dehydrating agent.

Is Propionic anhydride hazardous?

Propionic anhydride carries the GHS signal word "Danger". Main hazards: causes severe skin burns and eye damage. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Propionic anhydride?

Propionic anhydride is usually classified under HS code 291550 (Propionic acid, its salts and esters). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Propionic anhydride?

CompoundList lists 24 suppliers of Propionic anhydride in China, India, United States, Canada and 4 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Propionic anhydride in India?

8 suppliers in India list Propionic anhydride on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Propionic anhydride?

Suppliers quote Propionic anhydride on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Propionic anhydride

Get quotes for Propionic anhydride

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell Propionic anhydride
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of Propionic anhydride with a 3D view, its CAS number where known and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/propionic-anhydride-123-62-6" title="Propionic anhydride structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Synthetic aroma chemicals or HS code 291550

24 suppliers
Free quotes, contact stays private
Get quotes