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Propyzamide

Also known as Pronamide, 3,5-Dichloro-N-(1,1-dimethylpropynyl)benzamide, 3,5-dichloro-N-(2-methylbut-3-yn-2-yl)benzamide

Propyzamide chemical structure, C12H11Cl2NO, CAS 23950-58-5
2D chemical structure

Key facts

What buyers check first

Appearance
Off-white solid
Melting point
155 to 156
Solubility
In water - 15 mg/l (25 °C). In methanol, isopropanol 150, cyclohexanone, methyl ethyl ke…
HS code
292429
Category
Herbicides
UN number
UN 3077
Illustrative photo, off-white crystalline powder in fibre drums in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Propyzamide?

Plain description, key identifiers and synonyms

Propyzamide is a member of the class of benzamides resulting from the formal condensation of the carboxy group of 3,5-dichlorobenzoic acid with the amino group of 2-methylbut-3-yn-2-amine. It is used as a systemic post-emergent herbicide for the control grass and broadleaf weeds in a wide range of in a wide variety of fruit and root crops. It has a role as a herbicide and an agrochemical. It is a member of benzamides, a dichlorobenzene and a terminal acetylenic compound.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3,5-dichloro-N-(2-methylbut-3-yn-2-yl)benzamide
CAS number
23950-58-5 CAS number cross-checked
EC number
245-951-4
Molecular formula
C12H11Cl2NO
UNII
2EZ95375S0
MDL number
MFCD00055346
InChIKey
PHNUZKMIPFFYSO-UHFFFAOYSA-N
InChI
InChI=1S/C12H11Cl2NO/c1-4-12(2,3)15-11(16)8-5-9(13)7-10(14)6-8/h1,5-7H,2-3H3,(H,15,16)
SMILES (canonical and isomeric)
CC(C)(C#C)NC(=O)C1=CC(=CC(=C1)Cl)Cl

Synonyms

  • Pronamide
  • 3,5-Dichloro-N-(1,1-dimethylpropynyl)benzamide
  • 3,5-dichloro-N-(2-methylbut-3-yn-2-yl)benzamide
  • KERB
  • Pronamid
  • Clanex
  • 3,5-Dichloro-N-(1,1-dimethyl-2-propynyl)benzamide
  • KERB 50W
  • 3,5-Dichloro-N-(1,1-dimethylprop-2-ynyl)benzamide
  • RH 315
  • N-(1,1-Dimethylpropynyl)-3,5-dichlorobenzamide
  • Benzamide, 3,5-dichloro-N-(1,1-dimethyl-2-propynyl)-
  • propisamide
  • propizamide
  • Promamide
  • 3,5-Dichloro(N-1,1-dimethyl-2-propynyl)benzamide
  • Propyzamide, analytical standard
  • 3,5-dichloro-N-(1,1-dimethyl-2-propyn-1-yl)benzamide
  • Propyzamide Solution in Acetonitrile
  • RCRA waste number U192
  • RCRA waste no. U192
  • Rustler
  • Kerb Flo
  • Campbell's rapier
  • Kerb propyzamide 50
Show all 32 synonyms
  • 3,5-Dichloro-N-(2-methyl-3-butyn-2-yl)benzamide
  • 3,5-Dichloro-N-(1,1-dimethyl-2-propynyl) benzamide
  • 3,5-dichloro-N-(1,1-dimethylprop-2-yn-1-yl)benzamide
  • Phnuzkmipffyso-uhfffaoysa-
  • Pronamide (Kerb), analytical standard
  • Propyzamide 10 microg/mL in Cyclohexane
  • Propyzamide 100 microg/mL in Acetonitrile

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Off-white solidexp.
Odour
ODORLESSexp.
Melting point
155 to 156exp.
Solubility
In water - 15 mg/l (25 °C). In methanol, isopropanol 150, cyclohexanone, methyl ethyl ketone 200, dimethyl sulfoxide 330 (all in g/l). Moderately soluble in benzene, xylene, carbon tetrachloride. Sightly soluble in petroleum ether.exp.
Vapour pressure
8.5 × 10⁻⁵ MM HG @ 25 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
256.13 g/molcalc.
Exact mass
255.0218 Dacalc.
LogP (octanol/water)
3.14calc.
Topological polar surface area
29.1 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
2calc.
Heavy atoms
16calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.25calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS08: Serious health hazard
Serious health hazard
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H351Suspected of causing cancer.
  • H400Very toxic to aquatic life.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (7)
  • P203Obtain, read and follow all safety instructions before use.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P318If exposed or concerned, get medical advice.
  • P391Collect spillage.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 3077

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Propyzamide suppliers

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Propyzamide price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Selective herbicide that will control many broadleaf & grass weeds preemergence in lettuce (and other crops).

Selective systemic herbicide, .... used for the selective control of many annual and perennial grasses, and some broad- leaved weeds ....

Use classes: Herbicides, Pesticides, Pharmaceuticals.

Roles

  • agrochemical
  • herbicide
  • pesticide

Functional uses

  • Biocide

How it is made

Pronamide has been prepared by the Schotten-Bauman reaction of 3,5-dichlorobenzylchloride with 3-amino-3-methylbutyne.

Methylbutynol + ammonia + 3,5-dichlorobenzoyl chloride (ammoniation/amide formation)

Regulatory status

Inventories, regulations and trade controls that list this substance

Europe

  • EU harmonised classification (CLP Annex VI)
    Index no: 616-055-00-4

Health and food

  • EU Cosmetics Regulation Annex II, prohibited in cosmetics
    Name: Propyzamide, Ref no: 1049, Annex ref: II/1049

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Propyzamide is traded under.

HS 2924.29Indicative HS code

Cyclic amides (including cyclic carbamates) and their derivatives, salts thereof, other

World exports in 2024
$5.69B
−5.1% vs 2023, imports $5.8B
2019 to 2024
Top exporters
  1. China32.3%
  2. Switzerland * partner reported13.6%
  3. Norway * partner reported12.8%
Top importers
  1. United States15.9%
  2. Ireland15.8%
  3. Germany11.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Propyzamide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Propyzamide, based on the data on this page

What is Propyzamide?

Propyzamide is a member of the class of benzamides resulting from the formal condensation of the carboxy group of 3,5-dichlorobenzoic acid with the amino group of 2-methylbut-3-yn-2-amine.

What is the CAS number of Propyzamide?

The CAS registry number of Propyzamide is 23950-58-5.

What is the molecular formula and weight of Propyzamide?

The molecular formula of Propyzamide is C12H11Cl2NO and its molar mass is 256.13 g/mol.

What is Propyzamide used for?

Selective herbicide that will control many broadleaf & grass weeds preemergence in lettuce (and other crops). Selective systemic herbicide, .... used for the selective control of many annual and perennial grasses, and some broad- leaved weeds .... Use classes: Herbicides, Pesticides, Pharmaceuticals.

Is Propyzamide hazardous?

Propyzamide carries the GHS signal word "Warning". Main hazards: suspected of causing cancer, very toxic to aquatic life, very toxic to aquatic life with long lasting effects. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Propyzamide?

Propyzamide is usually classified under HS code 292429 (Cyclic amides (including cyclic carbamates) and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Propyzamide?

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Where can I buy Propyzamide in India?

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What is the price of Propyzamide?

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Guides for buyers

Practical guides that help when you source, ship or handle Propyzamide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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