CompoundList
Sign in
Herbicides

Quinolinic acid

Also known as Pyridine-2,3-dicarboxylic acid, 2,3-pyridinedicarboxylic acid, quinolinate

CAS 89-00-9Formula C7H5NO4Molar mass 167.12 g/molEC 201-874-8
GHS signal word: Danger. Pictograms: Corrosive, Harmful or irritant 123 suppliers listed
Get quotes Compare 123 suppliers
Quinolinic acid chemical structure, C7H5NO4, CAS 89-00-9
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Crystals
Melting point
228.5 °C
Solubility
Soluble in 180 parts water, in alkalies, slightly in alcohol. Almost insol in ether or b…
HS code
293339
Category
Herbicides
Illustrative photo, closed white HDPE bottles and amber jars on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Quinolinic acid?

Plain description, key identifiers and synonyms

Quinolinic acid is a pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan. It has a role as a NMDA receptor agonist, a mouse metabolite, an Escherichia coli metabolite and a human metabolite. It is a conjugate acid of a quinolinate and a quinolinate(1-).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
pyridine-2,3-dicarboxylic acid
CAS number
89-00-9 CAS number cross-checkedOther or deprecated CAS: 28605-84-7, 339155-13-4
EC number
201-874-8
Molecular formula
C7H5NO4
UNII
F6F0HK1URN
MDL number
MFCD00006295
InChIKey
GJAWHXHKYYXBSV-UHFFFAOYSA-N
InChI
InChI=1S/C7H5NO4/c9-6(10)4-2-1-3-8-5(4)7(11)12/h1-3H,(H,9,10)(H,11,12)
SMILES (canonical and isomeric)
C1=CC(=C(N=C1)C(=O)O)C(=O)O

Synonyms

  • Pyridine-2,3-dicarboxylic acid
  • 2,3-pyridinedicarboxylic acid
  • quinolinate
  • Pyridine-2,3-dicarboxylate
  • Pyridin-2,3-dicarbonsaeure
  • 2,3-pyridine dicarboxylic acid
  • pyridinedicarboxylic acid
  • Tocris-0225
  • pyridine-2,3-carboxylate
  • 2,3-pyridinedicarboxylate
  • quinolinic-acid
  • pyridine carboxylate, 6c
  • pyridine, 2,3-dicarboxy-
  • Quinolinic acid (Standard)
  • DivK1c_000773
  • Pyridine-2,3-dicarboxylicacid
  • pyridine-5,6-dicarboxylic acid
  • Moxifloxacin Impurity cent feminine
  • PDSP1_000133
  • PDSP2_000132
  • 2,3-Pyridinedicarboxylic acid, 99%
  • Sdccgmls-0411909.p028
  • Sdccgsbi-0050962.p003
  • 2,3-Pyridinedicarboxylic acid (8CI,9CI)
  • Quinolinic acid Solution in Methanol, 100ug/mL
Show all 27 synonyms
  • Quinolinic acid Solution in Methanol, 1000ug/mL
  • 2,3-Pyridinedicarboxylic acid, Vetec(TM) reagent grade, 98%

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystalsexp.
Odour
Odorlessexp.
Melting point
228.5 °Cexp.
Solubility
Soluble in 180 parts water, in alkalies, slightly in alcohol. Almost insol in ether or benzene.exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
167.12 g/molcalc.
Exact mass
167.0219 Dacalc.
LogP (octanol/water)
0.48calc.
Topological polar surface area
87.49 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
2calc.
Heavy atoms
12calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccncc1

c1ccncc1

1 ring, 6 atoms, the Pyridine ring system.

118,162 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS05: Corrosive
Corrosive
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
  • H315Causes skin irritation.
  • H318Causes serious eye damage.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (21)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P317Get medical help.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Quinolinic acid suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 123 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

123 suppliers in 15 countries

Send one request to many suppliers

Choose up to 10 suppliers or let us match your request. Compare quotes side by side, free.

Choose suppliersPost a request

Quinolinic acid price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Quinolinic acid (QUIN), a pyridine dicarboxylic acid and metabolite of tryptophan, which has been detected in the central nervous system (CNS), behaves as an excitotoxin /and is being used as a research tool to examine the role of excitotoxicity in neuronal degeneration associated with a number of neurological diseases (Alzheimer's disease, Huntington's disease, Parkinson's disease) which involve selective neurotransmitter deficits./.

Quinolinic acid levels in CSF (a surrogate marker of neuronal cell damage) / are used to evaluate HIV disease progression in research settings./.

Used to manufacture the herbicide Assert (imazapyr) ... and as an intermediate in the production of nicotinic acid.

Industrial uses: Intermediate.

Consumer uses: Intermediate.

Use classes: Cosmetics.

Roles

  • Escherichia coli metabolite
  • NMDA receptor agonist
  • animal metabolite
  • bacterial metabolite
  • eukaryotic metabolite
  • excitatory amino acid agonist
  • human metabolite
  • mammalian metabolite
  • metabolite
  • mouse metabolite
  • neurotransmitter agent
  • pharmaceutical
  • prokaryotic metabolite

Pharmacology

Quinolinic Acid is an intermediate product of the kynurenine pathway, which is responsible for the conversion of the amino acid tryptophan into nicotinamide adenine dinucleotide, with potential neurotoxic activity. If produced in excess, quinolinic acid can cross the blood-brain barrier (BBB) and function as an N-methyl-D-aspartate (NMDA) receptor agonist, which may lead to both neuronal damage and neurodegenerative brain disease. The NMDA receptor, a heterotetrameric, ligand-gated and voltage-dependent glutamate receptor, is critical for synaptic plasticity, learning and memory.

How it is made

Preparation: S. Hoogewerff, W. A. van Dorp, Ber. 12, 747 (1879), W. Koenigs, ibid. 983, O. fischer, E. Renouf, ibid. 17, 755 (1884), E. Sucharda, ibid. 58B, 1727(1925), v. Yu. Stiks, S. A. Bulgach, ibid. 65B, 11 (1932), A.F. Lindenstruth, C.A. VanderWerf, J. Am. Chem. Soc. 71, 3020 (1949).

Regulatory status

Inventories, regulations and trade controls that list this substance

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Quinolinic acid is traded under.

HS 2933.39Indicative HS code

Heterocyclic compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure…

World exports in 2024
$9.16B
−17.9% vs 2023, imports $10.6B
2019 to 2024
Top exporters
  1. China21.5%
  2. India * partner reported12.3%
  3. Ireland11.6%
Top importers
  1. Germany14.2%
  2. United States12.8%
  3. Brazil10.1%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Quinolinic acid is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Quinolinic acid, based on the data on this page

What is Quinolinic acid?

Quinolinic acid is a pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan. It has a role as a NMDA receptor agonist, a mouse metabolite, an Escherichia coli metabolite and a human metabolite.

What is the CAS number of Quinolinic acid?

The CAS registry number of Quinolinic acid is 89-00-9. Other or deprecated CAS numbers: 28605-84-7, 339155-13-4.

What is the molecular formula and weight of Quinolinic acid?

The molecular formula of Quinolinic acid is C7H5NO4 and its molar mass is 167.12 g/mol.

What is Quinolinic acid used for?

Quinolinic acid (QUIN), a pyridine dicarboxylic acid and metabolite of tryptophan, which has been detected in the central nervous system (CNS), behaves as an excitotoxin /and is being used as a research tool to examine the role of excitotoxicity in neuronal degeneration associated with a number of neurological disease…

Is Quinolinic acid hazardous?

Quinolinic acid carries the GHS signal word "Danger". Main hazards: harmful if swallowed, causes skin irritation, causes serious eye damage. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Quinolinic acid?

Quinolinic acid is usually classified under HS code 293339 (Compounds containing an unfused pyridine ring (whether or not hydrogenated) in the…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Quinolinic acid?

CompoundList lists 123 suppliers of Quinolinic acid in China, United States, Germany, United Kingdom and 11 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Quinolinic acid in India?

3 suppliers in India list Quinolinic acid on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Quinolinic acid?

Suppliers quote Quinolinic acid on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Quinolinic acid

Get quotes for Quinolinic acid

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell Quinolinic acid
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of Quinolinic acid with a 3D view, its CAS number where known and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/quinolinic-acid-89-00-9" title="Quinolinic acid structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Herbicides or HS code 293339

123 suppliers
Free quotes, contact stays private
Get quotes