Resolvin D2
Also known as RvD2, 7S,16R,17S-trihydroxy-4Z,8E,10Z,12E,14E,19Z-docosahexaenoic acid, (4Z,7R,8E,10Z,12E,14E,17S,19Z)-7,16,17-trihydroxy-4,8,10,12,14,19-docosahexaenoic acid
Key facts
What buyers check first
- CAS number
- 810668-37-2
- Formula
- C22H32O5
- Molar mass
- 376.49 g/mol
- HS code
- 291819
- Category
- Aliphatic and alicyclic building blocks
What is Resolvin D2?
Plain description, key identifiers and synonyms
Resolvin D2 is a member of the class of resolvins that is (4Z,8E,10Z,12E,14E,19Z)-docosahexaenoic acid carrying three hydroxy substituents at positions 7, 16 and 17 (the 7S,16R,17S-stereoisomer). It has a role as an estrogen receptor agonist, an anti-inflammatory agent, an anti-obesity agent, a human xenobiotic metabolite and a rat metabolite. It is a resolvin, a secondary allylic alcohol, a hydroxy polyunsaturated fatty acid and a triol. It is a conjugate acid of a resolvin D2(1-).
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- (4Z,7S,8E,10Z,12E,14E,16R,17S,19Z)-7,16,17-trihydroxydocosa-4,8,10,12,14,19-hexaenoic acid
- CAS number
- 810668-37-2Other or deprecated CAS: 578008-41-0
- Molecular formula
- C22H32O5
- InChIKey
- IKFAUGXNBOBQDM-XFMPMKITSA-N
- InChI
- InChI=1S/C22H32O5/c1-2-3-9-16-20(24)21(25)17-12-7-5-4-6-10-14-19(23)15-11-8-13-18-22(26)27/h3-12,14,17,19-21,23-25H,2,13,15-16,18H2,1H3,(H,26,27)/b6-4-,7-5+,9-3-,11-8-,14-10+,17-12+/t19-,20+,21-/m1/s1
- Canonical SMILES
- CCC=CCC(O)C(O)C=CC=CC=CC=CC(O)CC=CCCC(=O)O
- Isomeric SMILES
- CC/C=C\C[C@@H]([C@@H](/C=C/C=C/C=C\C=C\[C@H](C/C=C\CCC(=O)O)O)O)O
Synonyms
- RvD2
- 7S,16R,17S-trihydroxy-4Z,8E,10Z,12E,14E,19Z-docosahexaenoic acid
- (4Z,7R,8E,10Z,12E,14E,17S,19Z)-7,16,17-trihydroxy-4,8,10,12,14,19-docosahexaenoic acid
- RvD2 compound
- (4Z,7R,8E,10Z,12E,14E,16R,17S,19Z)-7,16,17-trihydroxydocosa-4,8,10,12,14,19-hexaenoic acid
- 7S,16R,17S-Trihydroxy-DHA
- (4Z,7R,8E,10Z,12E,14E,17S,19Z)-7,16,17-trihydroxydocosa-4,8,10,12,14,19-hexaenoic acid
- (4Z,7S,8E,10Z,12E,14E,16R,17S,19Z)-7,16,17-trihydroxydocosa-4,8,10,12,14,19-hexaenoate
- (4Z,7S,8E,10Z,12E,14E,16R,17S,19Z)-7,16,17-trihydroxydocosa-4,8,10,12,14,19-hexaenoic Acid
- Resolvin D2-[d5]
- (4Z,7S,8E,10Z,12E,14E,16R,17S,19Z)-7,16,17-Trihydroxy-4,8,10,12,14,19-docosahexaenoic acid
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 376.49 g/molcalc.Computed value |
|---|---|
| Exact mass | 376.225 Dacalc.Computed value |
| LogP (octanol/water) | 3.46calc.Computed value |
| Topological polar surface area | 97.99 Ųcalc.Computed value |
| Hydrogen bond donors | 4calc.Computed value |
| Hydrogen bond acceptors | 4calc.Computed value |
| Rotatable bonds | 14calc.Computed value |
| Heavy atoms | 27calc.Computed value |
| Rings | 0calc.Computed value |
| Aromatic rings | 0calc.Computed value |
| Fraction sp3 carbons | 0.41calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 3calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Safety and hazards
GHS classification summary, not a safety data sheet
No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Resolvin D2 suppliers
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Resolvin D2 price
Indicative price range per kg from live supplier offers
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Uses and applications
What the substance is used for, by industry and function
Industries and functions
Roles
- agonist
- animal metabolite
- anti-inflammatory agent
- anti-obesity agent
- estrogen receptor agonist
- eukaryotic metabolite
- human metabolite
- human xenobiotic metabolite
- mammalian metabolite
- metabolite
- rat metabolite
- xenobiotic metabolite
Pharmacology
Resolvin D2 is a polyunsaturated fatty acid in the resolvin family that is a poly-hydroxyl metabolite of docosahexaenoic acid (DHA), with potential anti-inflammatory, analgesic and protective activities.
Regulatory status
Inventories, regulations and trade controls that list this substance
No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Resolvin D2 is traded under.
Carboxylic acids with alcohol function but without other oxygen function, their…
- Germany11.7%
- South Korea9.8%
- Italy9.6%
* Partner reported figures, a lower bound.
The HS code shown for Resolvin D2 is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Resolvin D2, based on the data on this page
What is Resolvin D2?
What is the CAS number of Resolvin D2?
What is the molecular formula and weight of Resolvin D2?
What is Resolvin D2 used for?
Is Resolvin D2 hazardous?
What is the HS code of Resolvin D2?
Where can I buy Resolvin D2?
What is the price of Resolvin D2?
Guides for buyers
Practical guides that help when you source, ship or handle Resolvin D2
- Guide, Chemical identityCAS registry numbers explainedWhat a CAS number identifies, how the check digit works, why one chemical can have several numbers and what a CAS number cannot tell you about a product.Read
- Article, SourcingHow to write an RFQ that gets fast and accurate quotesWhat suppliers need to quote quickly and comparably: exact product identity, quantity and packing, delivery terms, documents, samples and payment, with a ready to use template.Read
- Guide, Trade and logisticsHS codes for chemicals and why they matterHow the Harmonized System classifies chemicals, the chapters that matter, the rules for chemically defined compounds and mixtures, and practical steps to find the right code.Read
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