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Subcategory of Building blocks and research compounds

Aliphatic and alicyclic building blocks

Acyclic and carbocyclic building blocks such as amino alcohols, cyclopropanes, cyclohexanes and bicyclic scaffolds.
Chemicals
34,180
Suppliers
4,657
Racks of small vials in a compound library
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About aliphatic and alicyclic building blocks

Aliphatic and alicyclic building blocks have no aromatic ring. The group covers functionalised alkyl chains such as amino alcohols, diamines, halo alkyl esters and alkynes, small rings such as cyclopropanes and cyclobutanes, cyclohexanes and other carbocycles, bicyclic and cage scaffolds such as bicyclo[1.1.1]pentanes and adamantanes, and linkers and spacers such as polyethylene glycol chains used in conjugates and degrader molecules.

Read more about aliphatic and alicyclic building blocks

Medicinal chemists use saturated building blocks to add three-dimensional shape, improve solubility and replace flat aromatic rings with bioisosteres. Bifunctional linkers are essential for antibody drug conjugates, PROTAC type degraders and surface chemistry.

Ask for purity by GC, NMR or LC-MS, stereochemistry and the ratio of cis and trans isomers where relevant, salt form, water and storage conditions. Some small strained rings and alkynes are reactive or volatile and need cold storage. Many compounds in this group lack a chromophore, so ask how purity was measured, since UV-based HPLC can miss impurities.

Top aliphatic and alicyclic building blocks

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Frequently asked questions

Quick answers about buying aliphatic and alicyclic building blocks on CompoundList.

What are aliphatic and alicyclic building blocks?

Acyclic and carbocyclic building blocks such as amino alcohols, cyclopropanes, cyclohexanes and bicyclic scaffolds.

How many aliphatic and alicyclic building blocks are listed on CompoundList?

CompoundList lists 34,180 chemicals in aliphatic and alicyclic building blocks. 4,657 suppliers offer products in this category.

Which aliphatic and alicyclic building blocks are the most popular?

The most searched and traded aliphatic and alicyclic building blocks on CompoundList include Acetylcholine chloride, Metformin hydrochloride, Deferoxamine, 2-Hydroxy-1,2,3-propanetricarboxylic acid hydrate (1:1) and 5-Aminolevulinic acid. They are part of the wider building blocks and research compounds family.

How do I buy aliphatic and alicyclic building blocks in bulk?

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