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Nucleosides and nucleotides

Ribavirin triphosphate

Also known as Ribavirin 5'-triphosphate, Virazole 5'-triphosphate, 1H-1,2,4-Triazole-3-carboxamide, 1-(5-O-(hydroxy((hydroxy(phosphonooxy)phosphinyl)oxy)phosphinyl)-beta-D-ribofuranosyl)-

CAS 63142-71-2Formula C8H15N4O14P3Molar mass 484.14 g/mol
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Ribavirin triphosphate chemical structure, C8H15N4O14P3, CAS 63142-71-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
63142-71-2
Formula
C8H15N4O14P3
Molar mass
484.14 g/mol
HS code
293499
Category
Nucleosides and nucleotides

What is Ribavirin triphosphate?

Plain description, key identifiers and synonyms

Ribavirin 5'-triphosphate is a 1-ribosyltriazole that is ribavirin in which the hydroxy group at the 5'-position is replaced by a triphosphate group. It is the active metabolite of the antiviral agent ribavirin. It has a role as a eukaryotic initiation factor 4F inhibitor, an EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor, an antiviral agent, a drug metabolite and a human blood serum metabolite. It is a primary carboxamide, a ribose triphosphate, a monocarboxylic acid amide, an aromatic amide and a 1-ribosyltriazole. It is functionally related to a ribavirin. It is a conjugate acid of a ribavirin 5'-triphosphate(4-).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
[[(2R,3S,4R,5R)-5-(3-carbamoyl-1,2,4-triazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
CAS number
63142-71-2 CAS number cross-checked
Molecular formula
C8H15N4O14P3
UNII
XA6L2VRY2M
InChIKey
MMJOCKKLRMRSEQ-AFCXAGJDSA-N
InChI
InChI=1S/C8H15N4O14P3/c9-6(15)7-10-2-12(11-7)8-5(14)4(13)3(24-8)1-23-28(19,20)26-29(21,22)25-27(16,17)18/h2-5,8,13-14H,1H2,(H2,9,15)(H,19,20)(H,21,22)(H2,16,17,18)/t3-,4-,5-,8-/m1/s1
Canonical SMILES
NC(=O)c1ncn(C2OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C2O)n1
Isomeric SMILES
C1=NC(=NN1[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)C(=O)N

Synonyms

  • Ribavirin 5'-triphosphate
  • Virazole 5'-triphosphate
  • 1H-1,2,4-Triazole-3-carboxamide, 1-(5-O-(hydroxy((hydroxy(phosphonooxy)phosphinyl)oxy)phosphinyl)-beta-D-ribofuranosyl)-
  • 1H-1,2,4-triazole-3-carboxamide, 1-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-beta-D-ribofuranosyl]-
  • Ribavirin-TP
  • RTP
  • Ribavirin 5'-Triphosphate Trisodium Salt
  • [[(2R,3S,4R,5R)-5-(3-carbamoyl-1,2,4-triazol-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate
  • 1-[5-O-(hydroxy{[hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl)-beta-D-ribofuranosyl]-1H-1,2,4-triazole-3-carboxamide
  • 1-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide-5'-triphosphate
  • [[(2R,3S,4R,5R)-5-(3-carbamoyl-1,2,4-triazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
  • 1mn9
  • RBV-TP
  • Ribavirin-5'-triphosphate
  • Hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-
  • Ribavirin 5'-triphosphate tetrasodium salt - 10mM aqueous solution
  • 1-beta-D-Ribofuranosyl-1,2,4-triazolo-3-carboxamide-5'-triphosphate
  • 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide-5'-triphosphate
  • 1-[5-O-[Hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-b- D-ribofuranosyl]-1H-1,2,4-triazole-3-carboxamide tetrasodium
  • 1-{5-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-ribofuranosyl}-1H-1,2,4-triazole-3-carboxamide
  • 1H-1,2,4-Triazole-3-carboxamide, 1-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-b-D-ribofuranosyl]-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
484.14 g/molcalc.
Exact mass
483.9798 Dacalc.
LogP (octanol/water)
-2.66calc.
Topological polar surface area
283.3 Ųcalc.
Hydrogen bond donors
7calc.
Hydrogen bond acceptors
12calc.
Rotatable bonds
9calc.
Heavy atoms
29calc.
Rings
2calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.63calc.
Formal charge
0calc.
Stereocentres
6calc.
Lipinski rule of five
Fails (2 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ncn(C2CCCO2)n1

c1ncn(C2CCCO2)n1

2 rings, 10 atoms.

61 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Ribavirin triphosphate suppliers

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Ribavirin triphosphate price

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Antiviral Agents

Roles

  • DNA polymerase inhibitor
  • animal metabolite
  • antimicrobial agent
  • antiviral agent
  • drug metabolite
  • enzyme inhibitor
  • eukaryotic initiation factor 4F inhibitor
  • eukaryotic metabolite
  • human blood serum metabolite
  • human metabolite
  • human xenobiotic metabolite
  • mammalian metabolite
  • metabolite
  • xenobiotic metabolite

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Ribavirin triphosphate is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Ribavirin triphosphate is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Ribavirin triphosphate, based on the data on this page

What is Ribavirin triphosphate?

Ribavirin 5'-triphosphate is a 1-ribosyltriazole that is ribavirin in which the hydroxy group at the 5'-position is replaced by a triphosphate group. It is the active metabolite of the antiviral agent ribavirin.

What is the CAS number of Ribavirin triphosphate?

The CAS registry number of Ribavirin triphosphate is 63142-71-2.

What is the molecular formula and weight of Ribavirin triphosphate?

The molecular formula of Ribavirin triphosphate is C8H15N4O14P3 and its molar mass is 484.14 g/mol.

What is Ribavirin triphosphate used for?

Known uses and roles of Ribavirin triphosphate include dna polymerase inhibitor, animal metabolite, antimicrobial agent, antiviral agent, drug metabolite and 10 more.

Is Ribavirin triphosphate hazardous?

No GHS hazard classification for Ribavirin triphosphate is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Ribavirin triphosphate?

Ribavirin triphosphate is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Ribavirin triphosphate?

CompoundList lists 1 supplier of Ribavirin triphosphate in China. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Ribavirin triphosphate?

Suppliers quote Ribavirin triphosphate on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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