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Alkaloids

Saxitoxin

Also known as Saxitoxin hydrate, Gonyaulax catenella poison, Saxidomus giganteus poison

CAS 35523-89-8Formula C10H17N7O4Molar mass 299.29 g/molEC 632-220-3
GHS signal word: Danger. Pictograms: Acute toxicity (severe) Prohibited, not for trade
Why it is not for trade
Saxitoxin chemical structure, C10H17N7O4, CAS 35523-89-8
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
35523-89-8
Formula
C10H17N7O4
Molar mass
299.29 g/mol
EC number
632-220-3
HS code
293980
Category
Alkaloids

What is Saxitoxin?

Plain description, key identifiers and synonyms

Saxitoxin is an alkaloid isolated from the marine dinoflagellates and cyanobacteria that causes paralytic shellfish poisoning. It has a role as a toxin, a sodium channel blocker, a neurotoxin, a marine metabolite and a cyanotoxin. It is a pyrrolopurine, a paralytic shellfish toxin, an alkaloid, a carbamate ester, a member of guanidines and a ketone hydrate. It is a conjugate base of a saxitoxin(2+).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
[(3aS,4R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,8,9-tetrahydro-1H-pyrrolo[1,2-c]purin-4-yl]methyl carbamate
CAS number
35523-89-8 CAS number cross-checkedOther or deprecated CAS: 73603-72-2
EC number
632-220-3
Molecular formula
C10H17N7O4
UNII
Q0638E899B
InChIKey
RPQXVSUAYFXFJA-HGRQIUPRSA-N
InChI
InChI=1S/C10H17N7O4/c11-6-15-5-4(3-21-8(13)18)14-7(12)17-2-1-9(19,20)10(5,17)16-6/h4-5,19-20H,1-3H2,(H2,12,14)(H2,13,18)(H3,11,15,16)/t4-,5-,10-/m0/s1
Canonical SMILES
NC(=O)OCC1N=C(N)N2CCC(O)(O)C23NC(N)=NC13
Isomeric SMILES
C1CN2C(=N[C@H]([C@H]3[C@]2(C1(O)O)NC(=N3)N)COC(=O)N)N

Synonyms

  • Saxitoxin hydrate
  • Gonyaulax catenella poison
  • Saxidomus giganteus poison
  • Mytilus californianus poison
  • 1H,10H-Pyrrolo(1,2-c)purine-10,10-diol, 2,6-diamino-4-(((aminocarbonyl)oxy)methyl)-3a,4,8,9-tetrahydro-, (3aS,4R,10aS)-
  • Gonyaulax Toxin
  • [(3aS,4R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,8,9-tetrahydro-1H-pyrrolo[1,2-c]purin-4-yl]methyl carbamate
  • [(3aS,4R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,8,9-tetrahydro-3H-pyrrolo[1,2-c]purin-4-yl]methyl carbamate
  • 1H,10H-Pyrrolo(1,2-c)purine-10,10-diol, 2,6-diamino-4-(((aminocarbonyl)oxy)methyl)-3a,4,8,9-tetrahydro-, (3aS-(3aalpha,4alpha,10aR*))-
  • Mitilotoxin
  • Saxitonin
  • Toxin, Gonyaulax
  • ((3aS,4R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,8,9-tetrahydro-1H-pyrrolo(1,2-c)purin-4-yl)methyl carbamate
  • ((3aS,4R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,8,9-tetrahydro-3H-pyrrolo(1,2-c)purin-4-yl)methyl carbamate
  • ((10,10-dihydroxy-2,6-diimino-decahydropyrrolo(1,2-c)purin-4-yl)methoxy)carboximidic acid
  • Saxitoxin-t
  • [(3aS,4R,10aS)-10,10-dihydroxy-2,6-diiminooctahydro-1H,8H-pyrrolo[1,2-c]purin-4-yl]methyl carbamate
  • Saxitoxin-3H
  • (+)-Saxitoxin
  • Saxitoxin (8CI)
  • Saxitoxin (hydrate)
  • US9174999, Table 1, Compound 1
  • 1H,10H-Pyrrolo(1,2-c)purine-10,10-diol, 2,6-diamino-4-(((amino-carbonyl)oxy)methyl)-3a,4,8,9-tetrahydro-, (3aS-(3a-alpha,4-alpha,10aR*))
  • 1H,10H-Pyrrolo(1,2-c)purine-10,10-diol, 2,6-diamino-4-(((aminocarbonyl)oxy)methyl)-3a,4,8,9-tetrahydro-, labeled with tritium, (3aS-(3aalpha,4alpha,10aR*))-
  • Saxitoxin in acetic acid (determination in mussel), BCR(R) certified Reference Material
Show all 26 synonyms
  • [(R,7aS,7bS)-2-amino-7,7-dihydroxy--imino-H,H,H,1H,5H,6H,7H,7bH-pyrrolo[1,2-c]purin--yl]methyl carbamate

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
299.29 g/molcalc.
Exact mass
299.1342 Dacalc.
LogP (octanol/water)
-3.85calc.
Topological polar surface area
184.8 Ųcalc.
Hydrogen bond donors
6calc.
Hydrogen bond acceptors
10calc.
Rotatable bonds
2calc.
Heavy atoms
21calc.
Rings
3calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.7calc.
Formal charge
0calc.
Stereocentres
3calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1=NCC2N=CNC23CCCN13

C1=NCC2N=CNC23CCCN13

3 rings, 12 atoms.

37 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)

Hazard statements

  • H300Fatal if swallowed.
  • H310Fatal in contact with skin.
  • H330Fatal if inhaled.
Precautionary statements (18)
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P262Do not get in eyes, on skin, or on clothing.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P284In case of inadequate ventilation wear respiratory protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P316Get emergency medical help immediately.
  • P320Specific treatment is urgent (see supplemental first aid instructions on the label).
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P361 + P364Take off immediately all contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Saxitoxin suppliers

Trading restrictions apply to this substance

Chemical Weapons Convention Schedule 1

Saxitoxin is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: OPCW Chemical Weapons Convention Schedule 1

Our policy on controlled substances

Saxitoxin price

Indicative price range per kg from live supplier offers

Prices are not shown for prohibited substances.

Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Poisons

Roles

  • aetiopathogenetic role
  • bacterial metabolite
  • biophysical role
  • cyanotoxin
  • marine metabolite
  • membrane transport modulator
  • metabolite
  • neurotoxin
  • poison
  • prokaryotic metabolite
  • sodium channel blocker
  • sodium channel modulator
  • toxin

Pharmacology

Saxitoxin is a carbamate alkaloid neurotoxin isolated from marine dinoflagellates and cyanobacteria that inhibits nerve conduction by blocking neuronal voltage-gated sodium channels in excitable cells. Exposure usually occurs through ingestion of contaminated shellfish, resulting in an illness called paralytic shellfish poisoning.

Regulatory status

Inventories, regulations and trade controls that list this substance

Chemical Weapons Convention Schedule 1

Saxitoxin is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: OPCW Chemical Weapons Convention Schedule 1

Our policy on controlled substances

Controls

  • Chemical Weapons Convention Schedule 1

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Saxitoxin is traded under.

HS 2939.80Indicative HS code

Natural or reproduced by synthesis, and their salts, esters and other derivatives not elsewhere classified…

World exports in 2024
$49.3M
+13.2% vs 2023, imports $61.4M
2019 to 2024
Top exporters
  1. China31.7%
  2. India * partner reported23.1%
  3. South Africa7.8%
Top importers
  1. Austria28.6%
  2. United States11.9%
  3. United Kingdom7.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Saxitoxin is indicative (it is known at chapter level only). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Saxitoxin, based on the data on this page

What is Saxitoxin?

Saxitoxin is an alkaloid isolated from the marine dinoflagellates and cyanobacteria that causes paralytic shellfish poisoning. It has a role as a toxin, a sodium channel blocker, a neurotoxin, a marine metabolite and a cyanotoxin.

What is the CAS number of Saxitoxin?

The CAS registry number of Saxitoxin is 35523-89-8. Other or deprecated CAS numbers: 73603-72-2.

What is the molecular formula and weight of Saxitoxin?

The molecular formula of Saxitoxin is C10H17N7O4 and its molar mass is 299.29 g/mol.

What is Saxitoxin used for?

Known uses and roles of Saxitoxin include aetiopathogenetic role, bacterial metabolite, biophysical role, cyanotoxin, marine metabolite and 9 more.

Is Saxitoxin hazardous?

Saxitoxin carries the GHS signal word "Danger". Main hazards: fatal if swallowed, fatal in contact with skin, fatal if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Saxitoxin?

Saxitoxin is usually classified under HS code 293980 (Alkaloids, natural or reproduced by synthesis, and their salts, ethers, esters and other…). This is indicative, confirm it with your customs broker before shipping.

Can I buy Saxitoxin on CompoundList?

No. Saxitoxin is on our prohibited list, so listings, quotes and messages for it are disabled. This page is kept for information only.

Guides for buyers

Practical guides that help when you source, ship or handle Saxitoxin

Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page

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