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Screening compounds

Solabegron

Also known as (R)-3'-((2-((2-(3-Chlorophenyl)-2-hydroxyethyl)amino)ethyl)amino)-[1,1'-biphenyl]-3-carboxylic acid, solabegronum, GW 427353

CAS 252920-94-8Formula C23H23ClN2O3Molar mass 410.90 g/mol
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Solabegron chemical structure, C23H23ClN2O3, CAS 252920-94-8
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
252920-94-8
Formula
C23H23ClN2O3
Molar mass
410.90 g/mol
HS code
292250
Category
Screening compounds

What is Solabegron?

Plain description, key identifiers and synonyms

Solabegron is a carboxybiphenyl that is [biphenyl]-3-carboxylic acid carrying a (2-{[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}ethyl)nitrilo group at the 3' position. A selective beta3-adrenergic receptor agonist currently in clinical development for the treatment of overactive bladder and irritable bowel syndrome. It has a role as a beta-adrenergic agonist. It is a carboxybiphenyl, a secondary alcohol, a substituted aniline, a secondary amino compound and a member of monochlorobenzenes.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3-[3-[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]ethylamino]phenyl]benzoic acid
CAS number
252920-94-8 CAS number cross-checked
Molecular formula
C23H23ClN2O3
UNII
55P6YH9O6N
MDL number
MFCD11040855
InChIKey
LLDXOPKUNJTIRF-QFIPXVFZSA-N
InChI
InChI=1S/C23H23ClN2O3/c24-20-8-2-6-18(13-20)22(27)15-25-10-11-26-21-9-3-5-17(14-21)16-4-1-7-19(12-16)23(28)29/h1-9,12-14,22,25-27H,10-11,15H2,(H,28,29)/t22-/m0/s1
Canonical SMILES
O=C(O)c1cccc(-c2cccc(NCCNCC(O)c3cccc(Cl)c3)c2)c1
Isomeric SMILES
C1=CC(=CC(=C1)C(=O)O)C2=CC(=CC=C2)NCCNC[C@@H](C3=CC(=CC=C3)Cl)O

Synonyms

  • (R)-3'-((2-((2-(3-Chlorophenyl)-2-hydroxyethyl)amino)ethyl)amino)-[1,1'-biphenyl]-3-carboxylic acid
  • solabegronum
  • GW 427353
  • 3-[3-[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]ethylamino]phenyl]benzoic acid
  • (1,1'-Biphenyl)-3-carboxylic acid, 3'-((2-(((2R)-2-(3-chlorophenyl)-2-hydroxyethyl)amino)ethyl)amino)-
  • 3'-[(2-{[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}ethyl)amino]-[1,1'-biphenyl]-3-carboxylic acid
  • (R)-3'-((2-((2-(3-chlorophenyl)-2-hydroxyethyl)amino)ethyl)amino)-(1,1'-biphenyl)-3-carboxylic acid
  • 3-(3-(2-(((2R)-2-(3-chlorophenyl)-2-hydroxyethyl)amino)ethylamino)phenyl)benzoic acid
  • (R)-3'-[[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]amino]ethyl]amino]-[1,1'-biphenyl]-3-carboxylic acid
  • 3'-((2-(((2R)-2-(3-chlorophenyl)-2-hydroxyethyl)amino)ethyl)amino)-(1,1'-biphenyl)-3-carboxylic acid
  • 3'-((2-((2-(3-Chlorophenyl)-2-hydroxyethyl)amino)ethyl)amino)-(1,1'-biphenyl)-3-carboxylic acid
  • [1,1'-Biphenyl]-3-carboxylicacid, 3'-[[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]ethyl]amino]-
  • [1,1'-Biphenyl]-3-carboxylicacid,3'-[[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]aMino]ethyl]aMino]-
  • GW 427353B
  • Solabegron (hydrochloride)
  • Solabegron?
  • compound 38
  • (R)-3'-(2-(2-(3-Chlorophenyl)-2-hydroxyethylamino)ethylamino)biphenyl-3-carboxylic acid
  • 3-[3-[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxy-ethyl]amino]ethylamino]phenyl]benzoic acid
  • 3'-((2-(((2R)-2-(3-Chlorophenyl)-2-hydroxyethyl)amino)ethyl)amino)biphenyl-3-carboxylic acid
  • 3'-[(2-{[(2r)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}ethyl)amino][1,1'-biphenyl]-3-carboxylic acid
  • 3'-[(2-{[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}ethyl)amino][biphenyl]-3-carboxylic acid

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
410.90 g/molcalc.
Exact mass
410.1397 Dacalc.
LogP (octanol/water)
4.44calc.
Topological polar surface area
81.59 Ųcalc.
Hydrogen bond donors
4calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
9calc.
Heavy atoms
29calc.
Rings
3calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.17calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(CCNCCNc2cccc(-c3ccccc3)c2)cc1

c1ccc(CCNCCNc2cccc(-c3ccccc3)c2)cc1

3 rings, 24 atoms.

2 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Solabegron suppliers

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Solabegron price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Adrenergic beta-3 Receptor Agonists

Roles

  • adrenergic agent
  • adrenergic agonist
  • beta-adrenergic agonist
  • beta-adrenergic drug
  • neurotransmitter agent
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Solabegron is traded under.

HS 2922.50Indicative HS code

Amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function

World exports in 2024
$3.29B
−5.9% vs 2023, imports $3.19B
2019 to 2024
Top exporters
  1. China39.2%
  2. United Kingdom27.1%
  3. India * partner reported4.8%
Top importers
  1. United States20.7%
  2. Germany7.6%
  3. Italy6.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Solabegron is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Solabegron, based on the data on this page

What is Solabegron?

Solabegron is a carboxybiphenyl that is [biphenyl]-3-carboxylic acid carrying a (2-{[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}ethyl)nitrilo group at the 3' position. A selective beta3-adrenergic receptor agonist currently in clinical development for the treatment of overactive bladder and irritable bowel syndrome.

What is the CAS number of Solabegron?

The CAS registry number of Solabegron is 252920-94-8.

What is the molecular formula and weight of Solabegron?

The molecular formula of Solabegron is C23H23ClN2O3 and its molar mass is 410.90 g/mol.

What is Solabegron used for?

Known uses and roles of Solabegron include building blocks in research and laboratory, screening compounds in research and laboratory, adrenergic agent, adrenergic agonist, beta-adrenergic agonist and 4 more.

Is Solabegron hazardous?

No GHS hazard classification for Solabegron is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Solabegron?

Solabegron is usually classified under HS code 292250 (Amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Solabegron?

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What is the price of Solabegron?

Suppliers quote Solabegron on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Solabegron

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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