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Rodenticides, nematicides and other pesticides

Strychnine

Also known as Strychnidin-10-one, (-)-Strychnine, Sanaseed

CAS 57-24-9Formula C21H22N2O2Molar mass 334.42 g/molEC 200-319-7
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Hazardous to the environment Controlled, licensed buyers only
Request as a licensed buyer Safety data
Strychnine chemical structure, C21H22N2O2, CAS 57-24-9
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Brilliant, colorless cubes from chloroform-ether
Melting point
284 °C
Boiling point
270 °C
Density
1.36 g/cm³ at 20 °C
Solubility
In water, 160 mg/L at 25 °C
HS code
293979
Category
Rodenticides, nematicides and other pesticides
UN number
UN 1692

What is Strychnine?

Plain description, key identifiers and synonyms

Strychnine is a monoterpenoid indole alkaloid that is strychnidine bearing a keto substituent at the 10-position. It has a role as a rodenticide, an avicide, a neurotransmitter agent, a cholinergic antagonist and a glycine receptor antagonist. It is an organic heteroheptacyclic compound and a monoterpenoid indole alkaloid. It is a conjugate base of a strychnine(1+). It derives from a hydride of a strychnidine.

Strychnine is a poisonous substance used as pesticide.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(4aR,5aS,8aR,13aS,15aS,15bR)-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinolin-14-one
CAS number
57-24-9 CAS number cross-checked
EC number
200-319-7
Molecular formula
C21H22N2O2
UNII
H9Y79VD43J
InChIKey
QMGVPVSNSZLJIA-FVWCLLPLSA-N
InChI
InChI=1S/C21H22N2O2/c24-18-10-16-19-13-9-17-21(6-7-22(17)11-12(13)5-8-25-16)14-3-1-2-4-15(14)23(18)20(19)21/h1-5,13,16-17,19-20H,6-11H2/t13-,16-,17-,19-,20-,21+/m0/s1
Canonical SMILES
O=C1CC2OCC=C3CN4CCC56c7ccccc7N1C5C2C3CC46
Isomeric SMILES
C1CN2CC3=CCO[C@H]4CC(=O)N5[C@H]6[C@H]4[C@H]3C[C@H]2[C@@]61C7=CC=CC=C75

Synonyms

  • Strychnidin-10-one
  • (-)-Strychnine
  • Sanaseed
  • Mole death
  • Strychninum
  • Gopher bait
  • Gopher-gitter
  • Boomer-rid
  • Hare-Rid
  • Certox
  • Mouse-tox
  • Kwik-kil
  • Ro-Dex
  • RCRA waste number P108
  • Stricnina
  • Strychnos
  • Mouse-nots
  • Mouse-rid
  • Dolco mouse cereal
  • Pied piper mouse seed
  • (4br,7as,8ar,13S,13ar,13bs)-5,6,7a,8,8a,11,13a,13b-octahydro-13H-13,14-ethano-7,9-methanooxepino(3,4-a)pyrrolo(2,3-d)carbazol-15-one
  • Strynchnos
  • (4aR,5aS,8aR,13aS,15aS,15bR)-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinolin-14-one
  • Nux-vomica
  • (1R,11S,18S,20R,21R,22S)-12-oxa-8,17-diazaheptacyclo(15.5.2.0^(1,18).0^(2,7).0^(8,22).0^(11,21).0^(15,20))tetracosa-2,4,6,14-tetraen-9-one
Show all 37 synonyms
  • (1R,11S,18S,20R,21R,22S)-12-oxa-8,17-diazaheptacyclo[15.5.2.0^{1,18}.0^{2,7}.0^{8,22}.0^{11,21}.0^{15,20}]tetracosa-2,4,6,14-tetraen-9-one
  • (4aR,5aS,8aR,13aS,15aS,15bR)-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo(3,2,1-ij)oxepino(2,3,4-de)pyrrolo(2,3-h)quinolin-14-one
  • (4bR,7aS,8aR,13S,13aR,13bS)-5,6,7a,8,8a,11,13a,13b-octahydro-13H-13,14-ethano-7,9-methanooxepino[3,4-a]pyrrolo[2,3-d]carbazol-15-one
  • Nitrate, Strychnine
  • (4aR,5aS,8aR,13aS,15aS,15bR)-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo(3,2,1-ij)oxepino(2,3,4-de)pyrrolo(2,3-h)quinoline-14-one
  • 12-oxa-8,17-diazaheptacyclo(15.5.2.01,18.02,7.08,22.011,21.015,20)tetracosa-2,4,6,14-tetraen-9-one
  • (4aR,4a1R,5aS,8aR,8a1S,15aS)-4a1,5,5a,7,8,8a1,15,15a-octahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinolin-14(4aH)-one
  • Estricnina
  • Strychinos
  • [3H]strychnine
  • (11S,18S,22S,1R,20R,21R)-12-oxa-8,17-diazaheptacyclo[15.5.2.0<1,18>.0<2,7>.0<8 ,22>.0<11,21>.0<15,20>]tetracosa-2,4,6,14-tetraen-9-one
  • Strychnin

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Brilliant, colorless cubes from chloroform-etherexp.
Odour
Odorlessexp.
Taste
Very bitter metallic tasteexp.
Melting point
284 °Cexp.
Boiling point
270 °Cexp.
Density
1.36 g/cm³ at 20 °Cexp.
Solubility
In water, 160 mg/L at 25 °Cexp.
Vapour pressure
VP: 0 torr at 20 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
334.42 g/molcalc.
Exact mass
334.1681 Dacalc.
LogP (octanol/water)
2.09calc.
Topological polar surface area
32.78 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
0calc.
Heavy atoms
25calc.
Rings
7calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.57calc.
Formal charge
0calc.
Stereocentres
6calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CC2OCC=C3CN4CCC56c7ccccc7N1C5C2C3CC46

O=C1CC2OCC=C3CN4CCC56c7ccccc7N1C5C2C3CC46

7 rings, 25 atoms.

93 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H300Fatal if swallowed.
  • H310Fatal in contact with skin.
  • H400Very toxic to aquatic life.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (14)
  • P262Do not get in eyes, on skin, or on clothing.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P302 + P352If on skin: Wash with plenty of water.
  • P316Get emergency medical help immediately.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P361 + P364Take off immediately all contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 1692
Transport hazard class
6.1
Packing group
I

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Strychnine suppliers

Controlled substance, listings of documented suppliers only, in the documented ranking

Pesticide toxic

Strychnine is controlled. Only documented suppliers can list it, and buyers must upload a valid licence with their request. Every request is reviewed before suppliers see it.

Licensed buyers only, every enquiry is reviewed by our compliance team.

Reference: Highly toxic substance

Our policy on controlled substances
No documented supplier lists it yet

Licensed buyers can post a request for Strychnine with their licence. Our compliance team reviews it before suppliers see it.

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Strychnine price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Chiefly in poison baits for rodents.

Used chiefly in poison baits set for squirrels, gophers, rabbits, and some lesser rodents. Baits are usually colored grains containing 0.5-1% of the sulfate.

Rodenticide.

Strychnine is a toxic alkaloid derived from the seeds of the treesStrychnos nux vomica,Strychnos ignatii(S. sancta Ingnatius), andStrychnos tiente(Upas tree), that can be found in India, southern Asia, northern Australia, and Hawaii. It was widely used in poison (toxic) baits to kill rodents and other mammals and is a common adulterant of many illicit (street) drugs. Exposure to strychnine can be fatal. It is odorless and has a bitter taste.

Use classes: Pharmaceuticals.

Pharmacological actions

  • Convulsants
  • Glycine Agents
  • Poisons

Roles

  • antagonist
  • avicide
  • cholinergic antagonist
  • cholinergic drug
  • glycine receptor antagonist
  • neurotransmitter agent
  • pesticide
  • pharmaceutical
  • rodenticide

Functional uses

  • Pharmaceutical

How it is made

Occurs most abundantly in seeds of Strychnos nux-vomica L., Loganiaceae and beans of S. ignatti, Berg.

By extraction of seeds of Strychnos spp with benzene in presence of calcium hydroxide, benzene extract is acidified and alkaloids ... recovered by alkali treatment. Strychnine is separated from crude alkaloids by crystallization from alc.

Extraction of the seeds of Nux vomica with acetic acid, filtration, precipitation by alkali and filtration.

Regulatory status

Inventories, regulations and trade controls that list this substance

Pesticide toxic

Strychnine is controlled. Only documented suppliers can list it, and buyers must upload a valid licence with their request. Every request is reviewed before suppliers see it.

Licensed buyers only, every enquiry is reviewed by our compliance team.

Reference: Highly toxic substance

Our policy on controlled substances

Europe

  • EU harmonised classification (CLP Annex VI)
    Index no: 614-003-00-5

Health and food

  • EU Cosmetics Regulation Annex II, prohibited in cosmetics
    Name: Strychnine and its salts, Ref no: 304, Annex ref: II/304

Other lists

  • Other regulatory list

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Strychnine is traded under.

HS 2939.79Indicative HS code

Alkaloids of vegetal origin, other than cocaine, ecgonine, salts, esters and other derivatives, not elsewhere…

World exports in 2024
$701M
+18.9% vs 2023, imports $830M
2019 to 2024
Top exporters
  1. Switzerland * partner reported25.3%
  2. Germany21.4%
  3. India * partner reported14.9%
Top importers
  1. United States20.9%
  2. Germany14.7%
  3. Italy14.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Strychnine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Strychnine, based on the data on this page

What is Strychnine?

Strychnine is a monoterpenoid indole alkaloid that is strychnidine bearing a keto substituent at the 10-position. It has a role as a rodenticide, an avicide, a neurotransmitter agent, a cholinergic antagonist and a glycine receptor antagonist.

What is the CAS number of Strychnine?

The CAS registry number of Strychnine is 57-24-9.

What is the molecular formula and weight of Strychnine?

The molecular formula of Strychnine is C21H22N2O2 and its molar mass is 334.42 g/mol.

What is Strychnine used for?

Chiefly in poison baits for rodents. Used chiefly in poison baits set for squirrels, gophers, rabbits, and some lesser rodents. Baits are usually colored grains containing 0.5-1% of the sulfate. Rodenticide. Strychnine is a toxic alkaloid derived from the seeds of the treesStrychnos nux vomica,Strychnos ignatii(S.

Is Strychnine hazardous?

Strychnine carries the GHS signal word "Danger". Main hazards: fatal if swallowed, fatal in contact with skin, very toxic to aquatic life. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Strychnine?

Strychnine is usually classified under HS code 293979 (Alkaloids, natural or reproduced by synthesis, and their salts, ethers, esters and other…). This is indicative, confirm it with your customs broker before shipping.

Can I buy Strychnine on CompoundList?

Strychnine is a controlled substance. Only documented suppliers can list it, and buyers must upload a valid licence with their request. Every request is reviewed by our compliance team before suppliers see it.

Guides for buyers

Practical guides that help when you source, ship or handle Strychnine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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