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Murcko scaffold

Ring system with 7 rings and 25 atoms

94 chemicals on CompoundList share this ring system.

Rings
7
Scaffold atoms
25
Chemicals
94
With full pages
24
Scaffold SMILES

O=C1CC2OCC=C3CN4CCC56c7ccccc7N1C5C2C3CC46

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CC2OCC=C3CN4CCC56c7ccccc7N1C5C2C3CC46

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 94 chemicals

Strychnine N-oxide chemical structure, C21H22N2O3, CAS 7248-28-4
Strychnine N-oxide
CAS 7248-28-4C21H22N2O3
Strychnidin-10-one, 2,3-dimethoxy-, hydrochloride (1:1) chemical structure, C23H27ClN2O4, CAS 5786-96-9
Strychnidin-10-one, 2,3-dimethoxy-, hydrochloride (1:1)
CAS 5786-96-9C23H27ClN2O4
2-Hydroxystrychnidin-10-one chemical structure, C21H22N2O3, CAS 19894-24-7
2-Hydroxystrychnidin-10-one
CAS 19894-24-7C21H22N2O3
N-Methylstrychnine chemical structure, C22H25N2O2+, CAS 47466-17-1
N-Methylstrychnine
CAS 47466-17-1C22H25N2O2+
Strychnidin-10-one, 2,3-dimethoxy-, [(1R)-1-methylheptyl 1,2-benzenedicarboxylate] (1:1) chemical structure, C39H48N2O8, CAS 68239-26-9
Strychnidin-10-one, 2,3-dimethoxy-, [(1R)-1-methylheptyl 1,2-benzenedicarboxylate] (1:1)
CAS 68239-26-9C39H48N2O8
Pseudo-beta-colubrine chemical structure, C22H24N2O4, CAS 29079-34-3
Pseudo-beta-colubrine
CAS 29079-34-3C22H24N2O4
22-Hydroxystrychnine chemical structure, C21H22N2O3, CAS 134250-41-2
22-Hydroxystrychnine
CAS 134250-41-2C21H22N2O3
16-Ethoxystrychnidin-10-one chemical structure, C23H26N2O3, CAS 5574-30-1
16-Ethoxystrychnidin-10-one
CAS 5574-30-1C23H26N2O3
19-Methyl-10-oxostrychnidin-19-ium chloride chemical structure, C22H25ClN2O2, CAS 2563-58-8
19-Methyl-10-oxostrychnidin-19-ium chloride
CAS 2563-58-8C22H25ClN2O2
N-(10-Oxostrychnidin-3-yl)ethanimidic acid chemical structure, C23H25N3O3, CAS 19452-88-1
N-(10-Oxostrychnidin-3-yl)ethanimidic acid
CAS 19452-88-1C23H25N3O3
16-Hydroxy-19-methyl-10-oxostrychnidin-19-ium chemical structure, C22H25N2O3+, CAS 19774-65-3
16-Hydroxy-19-methyl-10-oxostrychnidin-19-ium
CAS 19774-65-3C22H25N2O3+
4-Hydroxystrychnine chemical structure, C21H22N2O3, CAS 22595-26-2
4-Hydroxystrychnine
CAS 22595-26-2C21H22N2O3
3-Hydroxystrychnidin-10-one chemical structure, C21H22N2O3, CAS 27317-29-9
3-Hydroxystrychnidin-10-one
CAS 27317-29-9C21H22N2O3
3-Aminostrychnidin-10-one chemical structure, C21H23N3O2, CAS 27415-02-7
3-Aminostrychnidin-10-one
CAS 27415-02-7C21H23N3O2
Brucin chemical structure, C23H26N2O4, CAS 63428-84-2
Brucin
CAS 63428-84-2C23H26N2O4
N-Formylleucine-2,3-dimethoxystrychnidin-10-one chemical structure, C30H39N3O7, CAS 5327-71-9
N-Formylleucine-2,3-dimethoxystrychnidin-10-one
CAS 5327-71-9C30H39N3O7
10-Oxostrychnidine-2,3-diyl bis(dimethylcarbamate) chemical structure, C27H32N4O6, CAS 5464-67-5
10-Oxostrychnidine-2,3-diyl bis(dimethylcarbamate)
CAS 5464-67-5C27H32N4O6
beta-Colubrine chemical structure, C22H24N2O3, CAS 509-36-4
beta-Colubrine
CAS 509-36-4C22H24N2O3
(4aR,5aS,8aR,13aS,15aS,15bR)-10,11-Dihydroxy-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinolin-14-one chemical structure, C21H22N2O4
(4aR,5aS,8aR,13aS,15aS,15bR)-10,11-Dihydroxy-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinolin-14-one
C21H22N2O4
2'-Fluoro-5'-methyl-6-nitro[1,1'-biphenyl]-2-carboxylic acid--2,3-dimethoxystrychnidin-10-one (1/1) chemical structure, C37H36FN3O8, CAS 509-35-3
2'-Fluoro-5'-methyl-6-nitro[1,1'-biphenyl]-2-carboxylic acid--2,3-dimethoxystrychnidin-10-one (1/1)
CAS 509-35-3C37H36FN3O8
2,3-Dimethoxystrychnidin-10-one--heptonic acid (1/1) chemical structure, C30H40N2O12, CAS 5329-54-4
2,3-Dimethoxystrychnidin-10-one--heptonic acid (1/1)
CAS 5329-54-4C30H40N2O12
N-Formylvaline--2,3-dimethoxystrychnidin-10-one (1/1) chemical structure, C29H37N3O7, CAS 7505-32-0
N-Formylvaline--2,3-dimethoxystrychnidin-10-one (1/1)
CAS 7505-32-0C29H37N3O7
AO-080/43342692 chemical structure, C22H25N2O2+, CAS 105730-37-8
AO-080/43342692
CAS 105730-37-8C22H25N2O2+
Strychnine chemical structure, C21H22N2O2, CAS 57-24-9
Strychnine
CAS 57-24-9C21H22N2O2