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Succimer

Also known as meso-2,3-Dimercaptosuccinic acid, Dim-sa, meso-Dimercaptosuccinic acid

Succimer chemical structure, C4H6O4S2, CAS 304-55-2
2D chemical structure

Key facts

What buyers check first

CAS number
304-55-2
Formula
C4H6O4S2
Appearance
White crystals from aqueous methanol
Melting point
193 °C
HS code
293090
Category
Builders and chelating agents
Illustrative photo, colourless crystals beside a jumbo bulk bag in a chemical plant
Typical packagingIllustrative packaging image, not the actual product

What is Succimer?

Plain description, key identifiers and synonyms

Succimer is a sulfur-containing carboxylic acid that is succinic acid bearing two mercapto substituents at positions 2 and 3. A lead chelator used as an antedote to lead poisoning. It has a role as a chelator. It is a dithiol, a sulfur-containing carboxylic acid and a dicarboxylic acid.

Succimer is a medication used to treat lead, mercury, and arsenic poisoning.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2S,3R)-2,3-bis(sulfanyl)butanedioic acid
CAS number
304-55-2 CAS number cross-checked
EC number
206-155-2
Molecular formula
C4H6O4S2
UNII
DX1U2629QE
MDL number
MFCD00064799
InChIKey
ACTRVOBWPAIOHC-XIXRPRMCSA-N
InChI
InChI=1S/C4H6O4S2/c5-3(6)1(9)2(10)4(7)8/h1-2,9-10H,(H,5,6)(H,7,8)/t1-,2+
Canonical SMILES
O=C(O)C(S)C(S)C(=O)O
Isomeric SMILES
[C@@H]([C@@H](C(=O)O)S)(C(=O)O)S

Synonyms

  • meso-2,3-Dimercaptosuccinic acid
  • Dim-sa
  • meso-Dimercaptosuccinic acid
  • DMSA
  • Chemet
  • Succimero
  • Butanedioic acid, 2,3-dimercapto-, (2R,3S)-rel-
  • Succimerum
  • DMS-A
  • Ro 1-7977
  • (R*,S*)-2,3-Dimercaptobutanedioic acid
  • Butanedioic acid, 2,3-dimercapto-, (R*,S*)-
  • Succinic acid, 2,3-dimercapto-, meso-
  • (2R,3S)-2,3-disulfanylsuccinic acid
  • Acid, meso-Dimercaptosuccinic
  • Tin Dimercaptosuccinate
  • Tin Salt Succimer
  • Rhenium Salt Succimer
  • Disodium Salt Succimer
  • Acid, Dimercaptosuccinic
  • Dimercaptosuccinate, Tin
  • Monosodium Salt Succimer
  • Dipotassium Salt Succimer
  • meso Dimercaptosuccinic Acid
  • 2,3 Dimercaptosuccinic Acid
Show all 33 synonyms
  • Acid, 2,3-Dimercaptosuccinic
  • Meso 2, 3-Dimercaptosuccinic Acid
  • Ro 1 7977
  • (2R,3S)-rel-2,3-Dimercaptosuccinic acid
  • (2S,3R)-2,3-bis(sulfanyl)butanedioic acid
  • rel-(2R,3S)-2,3-Dimercaptobutanedioic acid
  • meso-2,3-Dimercaptobernsteinsaeure
  • (2R,3S)-2,3-dimercaptosuccinic acid

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
White crystals from aqueous methanolexp.
Odour
Unpleasant, characteristic mercaptan odorexp.
Taste
Unpleasant, characteristic mercaptan tasteexp.
Melting point
193 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
182.22 g/molcalc.
Exact mass
181.9708 Dacalc.
LogP (octanol/water)
-0.25calc.
Topological polar surface area
74.6 Ųcalc.
Hydrogen bond donors
4calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
3calc.
Heavy atoms
10calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.5calc.
Formal charge
0calc.
Stereocentres
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
  • H361Suspected of damaging fertility or the unborn child.
Precautionary statements (18)
  • P203Obtain, read and follow all safety instructions before use.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Succimer suppliers

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Where suppliers are based

80 suppliers in 15 countries

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Succimer price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Indicated for the treatment of lead poisoning in pediatric patients with blood lead levels above 45 mg/dL.

Chelating agent.

Therapeutic category: Antidote (heavy metal poisoning). (99m)Tc complex as diagnostic aid (radioactive imaging agent).

Pharmacological actions

  • Antidotes
  • Chelating Agents

Roles

  • antineoplastic agent
  • chelator
  • ligand
  • pharmaceutical

Pharmacology

Succimer is a Lead Chelator. The mechanism of action of succimer is as a Lead Chelating Activity.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Succimer is traded under.

HS 2930.90Indicative HS code

Organo-sulphur compounds, other

World exports in 2024
$5.83B
+0.1% vs 2023, imports $5.93B
2019 to 2024
Top exporters
  1. China40.7%
  2. United States10.9%
  3. Japan9.3%
Top importers
  1. United States13.3%
  2. Brazil12.6%
  3. China6.6%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Succimer is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Succimer, based on the data on this page

What is Succimer?

Succimer is a sulfur-containing carboxylic acid that is succinic acid bearing two mercapto substituents at positions 2 and 3. A lead chelator used as an antedote to lead poisoning. It has a role as a chelator. It is a dithiol, a sulfur-containing carboxylic acid and a dicarboxylic acid.

What is the CAS number of Succimer?

The CAS registry number of Succimer is 304-55-2.

What is the molecular formula and weight of Succimer?

The molecular formula of Succimer is C4H6O4S2 and its molar mass is 182.22 g/mol.

What is Succimer used for?

Indicated for the treatment of lead poisoning in pediatric patients with blood lead levels above 45 mg/dL. Chelating agent. Therapeutic category: Antidote (heavy metal poisoning). (99m)Tc complex as diagnostic aid (radioactive imaging agent).

Is Succimer hazardous?

Succimer carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Succimer?

Succimer is usually classified under HS code 293090 (Organo-sulphur compounds, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Succimer?

CompoundList lists 80 suppliers of Succimer in United States, China, Germany, United Kingdom and 11 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Succimer in India?

2 suppliers in India list Succimer on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Succimer?

Suppliers quote Succimer on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Succimer

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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