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Screening compounds

Temanogrel

Also known as Temanogrel hydrochloride, Temanogrel HCl, Apd791 hydrochloride

CAS 957466-27-2Formula C24H29ClN4O4Molar mass 472.97 g/mol
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Temanogrel chemical structure, C24H29ClN4O4, CAS 957466-27-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
957466-27-2
Formula
C24H29ClN4O4
Molar mass
472.97 g/mol
HS code
293499
Category
Screening compounds

What is Temanogrel?

Plain description, key identifiers and synonyms

Temanogrel Hydrochloride is the hydrochloride salt form of temanogrel, an orally bioavailable, selective inverse agonist of 5-hydroxytryptamine receptor 2A (5-HT2A), with potential anti-thrombotic and vasodilating activities. Upon oral administration, temanogrel targets, binds to and inhibits 5-HT2A expressed on platelet surfaces and in smooth muscle cells, thereby inhibiting 5-HT-mediated platelet aggregation and vasoconstriction. This may attenuate platelet aggregation and vasoconstriction, and improve blood flow.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3-methoxy-N-[3-(2-methylpyrazol-3-yl)-4-(2-morpholin-4-ylethoxy)phenyl]benzamide, hydrochloride
CAS number
957466-27-2 CAS number cross-checkedOther or deprecated CAS: 887936-68-7
Molecular formula
C24H29ClN4O4
UNII
5QEY8NZP3T
InChIKey
APWHJJLFCMBWQT-UHFFFAOYSA-N
InChI
InChI=1S/C24H28N4O4.ClH/c1-27-22(8-9-25-27)21-17-19(26-24(29)18-4-3-5-20(16-18)30-2)6-7-23(21)32-15-12-28-10-13-31-14-11-28;/h3-9,16-17H,10-15H2,1-2H3,(H,26,29);1H
SMILES (canonical and isomeric)
CN1C(=CC=N1)C2=C(C=CC(=C2)NC(=O)C3=CC(=CC=C3)OC)OCCN4CCOCC4.Cl

Synonyms

  • Temanogrel hydrochloride
  • Temanogrel HCl
  • Apd791 hydrochloride
  • Apd-791 hydrochloride
  • Temanogrel hydrochloride (USAN)
  • temanogrelum
  • 3-Methoxy-N-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(morpholin-4-yl)ethoxy)phenyl)benzamide monohydrochloride
  • Benzamide, 3-methoxy-N-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(4-morpholinyl)ethoxy)phenyl)-, hydrochloride (1:1)
  • 3-Methoxy-N-(3-(2-methyl-2H-pyrazol-3-yl)-4-(2-morpholin-4-yl-ethoxy)-phenyl)-benzamide
  • 3-Methoxy-N-[3-(2-methyl-2H-pyrazol-3-yl)-4-(2-morpholin-4-yl-ethoxy)-phenyl]-benzamide
  • Apd791
  • 3-Methoxy-N-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide hydrochloride
  • 3-methoxy-N-[3-(2-methylpyrazol-3-yl)-4-(2-morpholin-4-ylethoxy)phenyl]benzamide, hydrochloride
  • 3-Methoxy-N-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(morpholin-4- yl)ethoxy)phenyl)benzamide monohydrochloride
  • Benzamide, 3-methoxy-N-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(4- morpholinyl)ethoxy)phenyl)-, hydrochloride (1:1)
  • 4-(2-(4-(3-Methoxybenzamido)-2-(1-methyl-1H-pyrazol-5-yl)phenoxy)ethyl)morpholin-4-ium chloride
  • 3-Methoxy-N-{3-(1-methyl-1H-pyrazol-5-yl)-4-[2-(morpholin-4-yl)ethoxy]phenyl}benzamide--hydrogen chloride (1/1)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
472.97 g/molcalc.
Exact mass
472.1877 Dacalc.
LogP (octanol/water)
3.48calc.
Topological polar surface area
77.85 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
6calc.
Rotatable bonds
8calc.
Heavy atoms
33calc.
Rings
4calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.33calc.
Formal charge
0calc.
Stereocentres
0calc.
Components
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(Nc1ccc(OCCN2CCOCC2)c(-c2ccn[nH]2)c1)c1ccccc1

O=C(Nc1ccc(OCCN2CCOCC2)c(-c2ccn[nH]2)c1)c1ccccc1

4 rings, 29 atoms.

No other chemical in our database has this scaffold.

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Temanogrel suppliers

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Temanogrel price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Serotonin 5-HT2 Receptor Antagonists

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Temanogrel is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Temanogrel is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Temanogrel, based on the data on this page

What is Temanogrel?

Temanogrel Hydrochloride is the hydrochloride salt form of temanogrel, an orally bioavailable, selective inverse agonist of 5-hydroxytryptamine receptor 2A (5-HT2A), with potential anti-thrombotic and vasodilating activities.

What is the CAS number of Temanogrel?

The CAS registry number of Temanogrel is 957466-27-2. Other or deprecated CAS numbers: 887936-68-7.

What is the molecular formula and weight of Temanogrel?

The molecular formula of Temanogrel is C24H29ClN4O4 and its molar mass is 472.97 g/mol.

What is Temanogrel used for?

Known uses and roles of Temanogrel include building blocks in research and laboratory, screening compounds in research and laboratory and serotonin 5-ht2 receptor antagonists.

Is Temanogrel hazardous?

No GHS hazard classification for Temanogrel is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Temanogrel?

Temanogrel is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Temanogrel?

Post a free request on CompoundList and suppliers of Temanogrel will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Temanogrel?

Suppliers quote Temanogrel on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Temanogrel

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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