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Cosmetic antioxidants

Tetrahydrocurcumin

Also known as 1,7-bis(4-hydroxy-3-methoxyphenyl)heptane-3,5-dione, Sabiwhite, Tetrahydrodiferuloylmethane

CAS 36062-04-1Formula C21H24O6Molar mass 372.42 g/molEC 609-201-3
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Tetrahydrocurcumin chemical structure, C21H24O6, CAS 36062-04-1
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
36062-04-1
Formula
C21H24O6
Molar mass
372.42 g/mol
EC number
609-201-3
HS code
291450
Category
Cosmetic antioxidants

What is Tetrahydrocurcumin?

Plain description, key identifiers and synonyms

Tetrahydrocurcumin is a beta-diketone that is curcumin in which both of the double bonds have been reduced to single bonds. It has a role as a metabolite. It is a polyphenol, a beta-diketone and a diarylheptanoid. It is functionally related to a curcumin.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1,7-bis(4-hydroxy-3-methoxyphenyl)heptane-3,5-dione
CAS number
36062-04-1 CAS number cross-checked
EC number
609-201-3
Molecular formula
C21H24O6
UNII
00U0645U03
MDL number
MFCD04152347
INCI name
TETRAHYDROCURCUMIN, TETRAHYDRODIFERULOYLMETHANE
InChIKey
LBTVHXHERHESKG-UHFFFAOYSA-N
InChI
InChI=1S/C21H24O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h5-6,9-12,24-25H,3-4,7-8,13H2,1-2H3
SMILES (canonical and isomeric)
COC1=C(C=CC(=C1)CCC(=O)CC(=O)CCC2=CC(=C(C=C2)O)OC)O

Synonyms

  • 1,7-bis(4-hydroxy-3-methoxyphenyl)heptane-3,5-dione
  • Sabiwhite
  • Tetrahydrodiferuloylmethane
  • 3,5-Heptanedione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-
  • Tetrahydro Curcumin
  • 1,7-Bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanedione
  • Tetrahydrocucumin
  • HZIV 81-2
  • 1,7-bis(4-hydroxy-3-methoxy-phenyl)heptane-3,5-dione
  • 4-Hydrocurcumin
  • 1,7-Bis-(4-hydroxy-3-methoxy-phenyl)-heptane-3,5-dione
  • SabiWhite-
  • Tetrahydrocurcuminoids
  • Tetrahydrodi
  • Tetrahydrocurcumin (Standard)
  • Tetrahydro curcumin - Natural
  • Tetrahydro curcumin, Synthetic
  • Tetrahydro Curcumin (Mixture of Tautomeric Isomers)
  • 3,5-Heptamedopme. 1,7-bis(hydroxy-3methoxyphenyl)heptane
  • Tetrahydrocurcumin, >=96% (HPLC)
  • Tetrahydrocurcumin, analytical standard
  • 1,7-bis-(4'-hydroxy-3'-methoxyphenyl)-3,5-heptadione
  • TetrahydrocurcuminSabiwhite, Tetrahydro Curcumin, Tetrahydrodiferuloylmethane

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
372.42 g/molcalc.
Exact mass
372.1573 Dacalc.
LogP (octanol/water)
3.21calc.
Topological polar surface area
93.06 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
6calc.
Rotatable bonds
10calc.
Heavy atoms
27calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.33calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(CCc1ccccc1)CC(=O)CCc1ccccc1

O=C(CCc1ccccc1)CC(=O)CCc1ccccc1

2 rings, 21 atoms.

19 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Tetrahydrocurcumin suppliers

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All 58 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

58 suppliers in 9 countries

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Tetrahydrocurcumin price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Cosmetics.

Cosmetic ingredient, INCI name TETRAHYDRODIFERULOYLMETHANE(antioxidant)

Roles

  • metabolite

Functional uses

  • Antioxidant

Cosmetic functions

  • Antioxidant

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Tetrahydrocurcumin is traded under.

HS 2914.50Indicative HS code

Ketone-phenols and ketones with other oxygen function

World exports in 2024
$438M
+10.9% vs 2023, imports $420M
2019 to 2024
Top exporters
  1. China50.5%
  2. India * partner reported11.6%
  3. United States11.3%
Top importers
  1. United States20.8%
  2. Germany10.0%
  3. Netherlands8.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Tetrahydrocurcumin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Tetrahydrocurcumin, based on the data on this page

What is Tetrahydrocurcumin?

Tetrahydrocurcumin is a beta-diketone that is curcumin in which both of the double bonds have been reduced to single bonds. It has a role as a metabolite. It is a polyphenol, a beta-diketone and a diarylheptanoid. It is functionally related to a curcumin.

Guides for buyers

Practical guides that help when you source, ship or handle Tetrahydrocurcumin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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