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Herbicides

Thidiazuron

Also known as 1-Phenyl-3-(1,2,3-thiadiazol-5-yl)urea, Defolit, Dropp

CAS 51707-55-2Formula C9H8N4OSMolar mass 220.26 g/molEC 257-356-7
GHS signal word: Warning. Pictograms: Harmful or irritant, Hazardous to the environment 64 suppliers listed
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Thidiazuron chemical structure, C9H8N4OS, CAS 51707-55-2
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Colorless crystals
Melting point
210.5 to 212.5
Density
0.324 gm/cm³ at 20 °C /technical grade/
Solubility
In water, 20 mg/L at 23 °C
HS code
293499
Category
Herbicides
Illustrative photo, colourless crystals beside a jumbo bulk bag in a chemical plant
Typical packagingIllustrative packaging image, not the actual product

What is Thidiazuron?

Plain description, key identifiers and synonyms

Thidiazuron is a member of ureas.

Thidiazuron is a chemical compound and hormone.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1-phenyl-3-(thiadiazol-5-yl)urea
CAS number
51707-55-2 CAS number cross-checked
EC number
257-356-7
Molecular formula
C9H8N4OS
UNII
0091WH7STF
MDL number
MFCD00078723
InChIKey
HFCYZXMHUIHAQI-UHFFFAOYSA-N
InChI
InChI=1S/C9H8N4OS/c14-9(12-8-6-10-13-15-8)11-7-4-2-1-3-5-7/h1-6H,(H2,11,12,14)
SMILES (canonical and isomeric)
C1=CC=C(C=C1)NC(=O)NC2=CN=NS2

Synonyms

  • 1-Phenyl-3-(1,2,3-thiadiazol-5-yl)urea
  • Defolit
  • Dropp
  • 1-phenyl-3-(thiadiazol-5-yl)urea
  • N-Phenyl-N'-1,2,3-thiadiazol-5-ylurea
  • SN 49537
  • (N-1,2,3-Thiadiazolyl-5)-N'-phenylurea
  • N'-phenyl-N-(1,2,3-thiadiazol-5-yl)carbamimidic acid
  • Urea, N-phenyl-N'-1,2,3-thiadiazol-5-yl-
  • 5-Phenylcarbamoylamino-1,2,3-thiadiazole
  • TDZ
  • (phenylamino)-N-(1,2,3-thiadiazol-5-yl)carboxamide
  • Thidiauron
  • Avguron
  • Thidiazuran
  • N-Phenyl-N'-1,2,3-thiadiazol-5-yl-urea
  • Cambridge id 5282278
  • Urea, 1-phenyl-3-(1,2,3-thiadiazol-5-yl)-
  • Thidiazuron 100 |Ig/mL in Acetonitrile
  • Thidiazuron 100 microg/mL in Acetonitrile
  • n-phenyl-n'-(1,2,3-thiadiazol-5-yl)urea
  • N-phenyl-N'-1,2,3-thiadiazole-5-yl Urea
  • Thidiazuron, PESTANAL(R), analytical standard
  • Thidiazuron, plant cell culture tested, BioReagent

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Colorless crystalsexp.
Odour
Odorlessexp.
Melting point
210.5 to 212.5exp.
Density
0.324 gm/cm³ at 20 °C /technical grade/exp.
Solubility
In water, 20 mg/L at 23 °Cexp.
Vapour pressure
2.30 × 10⁻¹¹ mmHg at 25 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
220.26 g/molcalc.
Exact mass
220.0419 Dacalc.
LogP (octanol/water)
2.18calc.
Topological polar surface area
66.91 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
2calc.
Heavy atoms
15calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(Nc1ccccc1)Nc1cnns1

O=C(Nc1ccccc1)Nc1cnns1

2 rings, 15 atoms. This chemical is the scaffold itself.

17 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H312 + H332Harmful in contact with skin. Harmful if inhaled.
  • H312Harmful in contact with skin.
  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H332Harmful if inhaled.
  • H335May cause respiratory irritation.
  • H400Very toxic to aquatic life.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (19)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P317Get medical help.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Thidiazuron suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 64 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

64 suppliers in 10 countries

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Thidiazuron price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

For use on cotton.

It is used to defoliate cotton plants and has cytokinin activity.

Thidiazuron is a member of the phenylurea class of herbicides and is used as a growth regulator only on cotton.

Used for the defoliation of cotton, in order to facilitate harvesting, applied at 0.21 kg/ha per season.

Functional uses

  • Biocide

How it is made

Thidiazuron is produced from 5-amino-1,2,3-thiadiazol and phenyl isocyanate.

Preparation: H. Schulz, F. Arndt, DE 2214623, eidem, US 3883547 (1973, 1975 both to Schering AG).

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Thidiazuron is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Thidiazuron is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Thidiazuron, based on the data on this page

What is Thidiazuron?

Thidiazuron is a member of ureas.

What is the CAS number of Thidiazuron?

The CAS registry number of Thidiazuron is 51707-55-2.

What is the molecular formula and weight of Thidiazuron?

The molecular formula of Thidiazuron is C9H8N4OS and its molar mass is 220.26 g/mol.

What is Thidiazuron used for?

For use on cotton. It is used to defoliate cotton plants and has cytokinin activity. Thidiazuron is a member of the phenylurea class of herbicides and is used as a growth regulator only on cotton. Used for the defoliation of cotton, in order to facilitate harvesting, applied at 0.21 kg/ha per season.

Is Thidiazuron hazardous?

Thidiazuron carries the GHS signal word "Warning". Main hazards: harmful in contact with skin. harmful if inhaled, harmful in contact with skin, causes skin irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Thidiazuron?

Thidiazuron is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Thidiazuron?

CompoundList lists 64 suppliers of Thidiazuron in China, Brazil, United States, Belarus and 6 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Thidiazuron?

Suppliers quote Thidiazuron on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Thidiazuron

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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