CompoundList
Sign in
Analytical reagents

Thymolphthalein

Also known as Thymophthalein, 1(3H)-Isobenzofuranone, 3,3-bis[4-hydroxy-2-methyl-5-(1-methylethyl)phenyl]-, Phenolphthalein, 5',5''-diisopropyl-2',2''-dimethyl-

CAS 125-20-2Formula C28H30O4Molar mass 430.54 g/molEC 204-729-7
GHS signal word: Danger. Pictograms: Serious health hazard 37 suppliers listed
Get quotes Compare 37 suppliers
Thymolphthalein chemical structure, C28H30O4, CAS 125-20-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
125-20-2
Formula
C28H30O4
Molar mass
430.54 g/mol
EC number
204-729-7
HS code
293220
Category
Analytical reagents

What is Thymolphthalein?

Plain description, key identifiers and synonyms

Thymophthalein is a terpene lactone.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3,3-bis(4-hydroxy-2-methyl-5-propan-2-ylphenyl)-2-benzofuran-1-one
CAS number
125-20-2 CAS number cross-checked
EC number
204-729-7
Molecular formula
C28H30O4
UNII
YG5I28WSQP
MDL number
MFCD00005909
InChIKey
LDKDGDIWEUUXSH-UHFFFAOYSA-N
InChI
InChI=1S/C28H30O4/c1-15(2)20-13-23(17(5)11-25(20)29)28(22-10-8-7-9-19(22)27(31)32-28)24-14-21(16(3)4)26(30)12-18(24)6/h7-16,29-30H,1-6H3
SMILES (canonical and isomeric)
CC1=CC(=C(C=C1C2(C3=CC=CC=C3C(=O)O2)C4=CC(=C(C=C4C)O)C(C)C)C(C)C)O

Synonyms

  • Thymophthalein
  • 1(3H)-Isobenzofuranone, 3,3-bis[4-hydroxy-2-methyl-5-(1-methylethyl)phenyl]-
  • Phenolphthalein, 5',5''-diisopropyl-2',2''-dimethyl-
  • 3,3-Bis(4-hydroxy-5-isopropyl-o-tolyl)phthalide
  • 1(3H)-Isobenzofuranone, 3,3-bis(4-hydroxy-2-methyl-5-(1-methylethyl)phenyl)-
  • 3,3-bis(4-hydroxy-2-methyl-5-propan-2-ylphenyl)-2-benzofuran-1-one
  • 3,3-bis(4-hydroxy-5-isopropyl-2-methylphenyl)isobenzofuran-1(3H)-one
  • 5',5''-Diisopropyl-2',2''-dimethylphenolphthalein
  • 3,3-Bis[4-hydroxy-2-methyl-5-(1-methylethyl)phenyl]-1(3H)-isobenzofuranone
  • 3,3-bis(4-hydroxy-5-isopropyl-2-methyl-phenyl)isobenzofuran-1-one
  • 3,3-bis[4-hydroxy-2-methyl-5-(propan-2-yl)phenyl]-2-benzofuran-1(3H)-one
  • 3,3-bis[4-hydroxy-2-methyl-5-(methylethyl)phenyl]-3-hydroisobenzofuran-1-one
  • thymolphthaleine
  • 3,3-Bis(4-hydroxy-2-methyl-5-(1-methylethyl)phenyl)-1(3H)-isobenzofuranone
  • Thymolphthalein solution
  • Thymolphthalein ACS grade
  • Thymolphthalein, ACS grade
  • Thymolphthalein, acs
  • pH Indicator (9.3-10.5)
  • Thymolphthalein, JIS special grade
  • Thymolphthalein, p.a., ACS reagent
  • 3,3-Bis(4-hydroxy-5-isopropyl-2-methylphenyl)-2-benzofuran-1(3H)-one
  • 3,3-bis[4-hydroxy-2-methyl-5-(propan-2-yl)phenyl]-1,3-dihydro-2-benzofuran-1-one
  • Thymolphthalein Solution in Methanol, 100ug/mL
  • Thymolphthalein Solution in Methanol, 1000ug/mL
Show all 34 synonyms
  • Thymolphthalein, ACS reagent, Dye content 95 %
  • Phenolphthalein,5''-diisopropyl-2',2''-dimethyl-
  • 5',5''-Diisopropyl-2',2''-dimethyl- phenolphthalein
  • Thymolphthalein, ACS reagent, indicator (pH 8.8-10.5)
  • 2',2''-Diisopropyl-5',5''-dimethylphenolphthalein
  • 3,3-Bis(4-hydroxy-3-isopropyl-6-methyl)phthalide
  • 3,3-bis(4-hydroxy-2-methyl-5-propan-2-ylphenyl)-1-isobenzofuranone
  • 3,3-Bis(4-hydroxy-5-isopropyl-2-methylphenyl)isobenzofuran-1-one
  • 1(3H)-Isobenzofuranone,3-bis[4-hydroxy-2-methyl-5-(1-methylethyl)phenyl]-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
430.54 g/molcalc.
Exact mass
430.2144 Dacalc.
LogP (octanol/water)
6.42calc.
Topological polar surface area
66.76 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
4calc.
Heavy atoms
32calc.
Rings
4calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.32calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1OC(c2ccccc2)(c2ccccc2)c2ccccc21

O=C1OC(c2ccccc2)(c2ccccc2)c2ccccc21

4 rings, 22 atoms, the RefChem:357140 ring system.

146 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H341Suspected of causing genetic defects.
  • H350May cause cancer.
  • H361Suspected of damaging fertility or the unborn child.
Precautionary statements (5)
  • P203Obtain, read and follow all safety instructions before use.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P318If exposed or concerned, get medical advice.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Thymolphthalein suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 37 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

37 suppliers in 9 countries

Send one request to many suppliers

Choose up to 10 suppliers or let us match your request. Compare quotes side by side, free.

Choose suppliersPost a request

Thymolphthalein price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Industrial uses: Dye.

Pharmacological actions

  • Coloring Agents
  • Indicators and Reagents

Functional uses

  • Dye

Regulatory status

Inventories, regulations and trade controls that list this substance

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Thymolphthalein is traded under.

HS 2932.20Indicative HS code

Lactones

World exports in 2024
$1.97B
−4.7% vs 2023, imports $2.07B
2019 to 2024
Top exporters
  1. China56.3%
  2. India * partner reported7.4%
  3. Germany7.3%
Top importers
  1. United States14.2%
  2. India * partner reported13.5%
  3. Brazil8.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Thymolphthalein is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Thymolphthalein, based on the data on this page

What is Thymolphthalein?

Thymophthalein is a terpene lactone.

What is the CAS number of Thymolphthalein?

The CAS registry number of Thymolphthalein is 125-20-2.

What is the molecular formula and weight of Thymolphthalein?

The molecular formula of Thymolphthalein is C28H30O4 and its molar mass is 430.54 g/mol.

What is Thymolphthalein used for?

Industrial uses: Dye.

Is Thymolphthalein hazardous?

Thymolphthalein carries the GHS signal word "Danger". Main hazards: suspected of causing genetic defects, may cause cancer, suspected of damaging fertility or the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Thymolphthalein?

Thymolphthalein is usually classified under HS code 293220 (Lactones). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Thymolphthalein?

CompoundList lists 37 suppliers of Thymolphthalein in India, United States, China, Egypt and 5 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Thymolphthalein in India?

15 suppliers in India list Thymolphthalein on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Thymolphthalein?

Suppliers quote Thymolphthalein on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Thymolphthalein

Get quotes for Thymolphthalein

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell Thymolphthalein
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of Thymolphthalein with a 3D view, its CAS number where known and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/thymolphthalein-125-20-2" title="Thymolphthalein structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Analytical reagents or HS code 293220

37 suppliers
Free quotes, contact stays private
Get quotes