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Screening compounds

Tilmacoxib

Also known as Benzenesulfonamide, 4-(4-cyclohexyl-2-methyl-5-oxazolyl)-2-fluoro-, 4-(4-Cyclohexyl-2-methyloxazol-5-yl)-2-fluorobenzenesulfonamide, 4-(4-cyclohexyl-2-methyl-1,3-oxazol-5-yl)-2-fluorobenzenesulfonamide

CAS 180200-68-4Formula C16H19FN2O3SMolar mass 338.40 g/mol
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Tilmacoxib chemical structure, C16H19FN2O3S, CAS 180200-68-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
180200-68-4
Formula
C16H19FN2O3S
Molar mass
338.40 g/mol
HS code
293590
Category
Screening compounds

What is Tilmacoxib?

Plain description, key identifiers and synonyms

Tilmacoxib is a member of the class of 1,3-oxazoles that is that is 1,3-oxazole which is substituted at positions 2, 4 and 5 by methyl, cyclohexyl, and 3-fluoro-4-sulfamoylphenyl groups, respectively. It has a role as a cyclooxygenase 2 inhibitor. It is a sulfonamide, an organofluorine compound and a member of 1,3-oxazoles.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
4-(4-cyclohexyl-2-methyl-1,3-oxazol-5-yl)-2-fluorobenzenesulfonamide
CAS number
180200-68-4 CAS number cross-checked
Molecular formula
C16H19FN2O3S
UNII
G6VI5P84SX
MDL number
MFCD00949394
InChIKey
MIMJSJSRRDZIPW-UHFFFAOYSA-N
InChI
InChI=1S/C16H19FN2O3S/c1-10-19-15(11-5-3-2-4-6-11)16(22-10)12-7-8-14(13(17)9-12)23(18,20)21/h7-9,11H,2-6H2,1H3,(H2,18,20,21)
SMILES (canonical and isomeric)
CC1=NC(=C(O1)C2=CC(=C(C=C2)S(=O)(=O)N)F)C3CCCCC3

Synonyms

  • Benzenesulfonamide, 4-(4-cyclohexyl-2-methyl-5-oxazolyl)-2-fluoro-
  • 4-(4-Cyclohexyl-2-methyloxazol-5-yl)-2-fluorobenzenesulfonamide
  • 4-(4-cyclohexyl-2-methyl-1,3-oxazol-5-yl)-2-fluorobenzenesulfonamide
  • tilmacoxibum
  • 5-ethoxymethyl-7-fluoro-3-oxo-1,2,3,5-tetrahydrobenzo(4,5)imidazo(1,2a)pyridine-4-N-(2-fluorophenyl)carboxamide
  • 4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-2-fluoro-benzenesulfonamide
  • JTE522, JTP19605, RWJ57504
  • Tiracoxib
  • Tilmacoxib (JAN/USAN/INN)
  • 4-(4-cyclohexyl-2-methyl-1,3-oxazol-5-yl)-2-fluorobenzene-1-sulfonamide
  • 4-(4-cyclohexyl-2-methyl-5-oxazolyl)-2-fluorobenzenesulfonamide
  • 5-(4-aminosulfonyl-3-fluorophenyl)-4-cyclohexyl-2-methyloxazole

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
338.40 g/molcalc.
Exact mass
338.11 Dacalc.
LogP (octanol/water)
3.48calc.
Topological polar surface area
86.19 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
3calc.
Heavy atoms
23calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.44calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(-c2ocnc2C2CCCCC2)cc1

c1ccc(-c2ocnc2C2CCCCC2)cc1

3 rings, 17 atoms.

4 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Tilmacoxib suppliers

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Tilmacoxib price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • cyclooxygenase 2 inhibitor
  • enzyme inhibitor

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Tilmacoxib is traded under.

HS 2935.90Indicative HS code

Sulphonamides, other

World exports in 2024
$5.64B
−11.0% vs 2023, imports $8.56B
2019 to 2024
Top exporters
  1. Ireland43.1%
  2. China12.0%
  3. India * partner reported9.5%
Top importers
  1. United States23.6%
  2. Slovenia19.1%
  3. Spain11.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Tilmacoxib is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Tilmacoxib, based on the data on this page

What is Tilmacoxib?

Tilmacoxib is a member of the class of 1,3-oxazoles that is that is 1,3-oxazole which is substituted at positions 2, 4 and 5 by methyl, cyclohexyl, and 3-fluoro-4-sulfamoylphenyl groups, respectively. It has a role as a cyclooxygenase 2 inhibitor.

What is the CAS number of Tilmacoxib?

The CAS registry number of Tilmacoxib is 180200-68-4.

What is the molecular formula and weight of Tilmacoxib?

The molecular formula of Tilmacoxib is C16H19FN2O3S and its molar mass is 338.40 g/mol.

What is Tilmacoxib used for?

Known uses and roles of Tilmacoxib include building blocks in research and laboratory, screening compounds in research and laboratory, cyclooxygenase 2 inhibitor and enzyme inhibitor.

Is Tilmacoxib hazardous?

No GHS hazard classification for Tilmacoxib is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Tilmacoxib?

Tilmacoxib is usually classified under HS code 293590 (Sulphonamides, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Tilmacoxib?

Post a free request on CompoundList and suppliers of Tilmacoxib will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Tilmacoxib?

Suppliers quote Tilmacoxib on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Tilmacoxib

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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