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Cardiovascular and metabolic drugs

Trapidil

Also known as Rocornal, Trapymin, N,N-diethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

CAS 15421-84-8Formula C10H15N5Molar mass 205.27 g/molEC 239-434-2
GHS signal word: Warning. Pictograms: Harmful or irritant 16 suppliers listed
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Trapidil chemical structure, C10H15N5, CAS 15421-84-8
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
15421-84-8
Formula
C10H15N5
Molar mass
205.27 g/mol
EC number
239-434-2
HS code
293359
Category
Cardiovascular and metabolic drugs

What is Trapidil?

Plain description, key identifiers and synonyms

Trapidil is a member of triazolopyrimidines.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
N,N-diethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
CAS number
15421-84-8 CAS number cross-checked
EC number
239-434-2
Molecular formula
C10H15N5
UNII
EYG5Y6355E
MDL number
MFCD00193104
InChIKey
GSNOZLZNQMLSKJ-UHFFFAOYSA-N
InChI
InChI=1S/C10H15N5/c1-4-14(5-2)9-6-8(3)13-10-11-7-12-15(9)10/h6-7H,4-5H2,1-3H3
SMILES (canonical and isomeric)
CCN(CC)C1=CC(=NC2=NC=NN12)C

Synonyms

  • Rocornal
  • Trapymin
  • N,N-diethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
  • AR 12008
  • Trapidilum
  • (1,2,4)Triazolo(1,5-a)pyrimidin-7-amine, N,N-diethyl-5-methyl-
  • [1,2,4]Triazolo[1,5-a]pyrimidin-7-amine, N,N-diethyl-5-methyl-
  • N,N-diethyl-5-methyl-(1,2,4)triazolo(1,5-a)pyrimidin-7-amine
  • 7-Diethylamino-5-methyl(1,2,4)triazolo(1,5-a)pyrimidine
  • Rocornal (TN)
  • 7-Diethylamino-5-methyl-s-triazolo(1,5-a)pyrimidine
  • Avantrin
  • [1,2,4]Triazolo[1,5-a]pyrimidin-7-amine,N,N-diethyl-5-methyl-
  • N,N-Diethyl-5-methyl-(1,2,4)triazolo(1,5-a)pyrimidine-7-amine
  • s-Triazolo(1,5-a)pyrimidin-7-amine, N,N-diethyl-5-methyl-
  • N,N-Diethyl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
  • 7-(Diethylamino)-5-methyl-2-triazolo[1,5-a]pyrimidine
  • Trapidil CRS
  • Trapidil (Standard)
  • 5-Methyl-7-diethylamino-s-triazolo-(1,5-a)-pyrimidine
  • 5-Methyl-7-diaethylamino-s-triazolo(1.5-a)pyrimidin
  • Trapidil (JP18/INN)
  • Trapidil, >=98% (HPLC)
  • 7-(Diethylamino)-5-methyl-s-triazolo(1,5-a)pyrimidine
  • N,N-Diethyl-5-methyl-[1,2,4]triazolo[5,1-b]pyrimidin-7-amine

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
205.27 g/molcalc.
Exact mass
205.1327 Dacalc.
LogP (octanol/water)
1.28calc.
Topological polar surface area
46.32 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
3calc.
Heavy atoms
15calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.5calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1cnc2ncnn2c1

c1cnc2ncnn2c1

2 rings, 9 atoms, the 1,2,4-Triazolo(1,5-a)pyrimidine ring system.

609 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Trapidil suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 16 suppliers
16 of 16 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

16 suppliers in 7 countries

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Trapidil price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Phosphodiesterase Inhibitors
  • Platelet Aggregation Inhibitors
  • Vasodilator Agents

Roles

  • cardiovascular drug
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Trapidil is traded under.

HS 2933.59Indicative HS code

Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring, other

World exports in 2024
$18.4B
+10.5% vs 2023, imports $24.8B
2019 to 2024
Top exporters
  1. Ireland43.6%
  2. Switzerland * partner reported26.3%
  3. China7.9%
Top importers
  1. Slovenia30.3%
  2. United States30.1%
  3. Germany15.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Trapidil is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Trapidil, based on the data on this page

What is Trapidil?

Trapidil is a member of triazolopyrimidines.

What is the CAS number of Trapidil?

The CAS registry number of Trapidil is 15421-84-8.

What is the molecular formula and weight of Trapidil?

The molecular formula of Trapidil is C10H15N5 and its molar mass is 205.27 g/mol.

What is Trapidil used for?

Known uses and roles of Trapidil include cardiovascular drugs in pharmaceuticals, cardiovascular drug, pharmaceutical, phosphodiesterase inhibitors, platelet aggregation inhibitors and 1 more.

Is Trapidil hazardous?

Trapidil carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Trapidil?

Trapidil is usually classified under HS code 293359 (Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Trapidil?

CompoundList lists 16 suppliers of Trapidil in United States, China, France, Germany and 3 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Trapidil in India?

1 supplier in India list Trapidil on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Trapidil?

Suppliers quote Trapidil on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Trapidil

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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