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Central nervous system drugs

Tyramine

Also known as 4-(2-Aminoethyl)phenol, Uteramine, 2-(4-Hydroxyphenyl)ethylamine

CAS 51-67-2Formula C8H11NOMolar mass 137.18 g/molEC 200-115-8
GHS signal word: Warning. Pictograms: Harmful or irritant 105 suppliers listed
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Tyramine chemical structure, C8H11NO, CAS 51-67-2
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Crystals from benzene or alcohol
Melting point
164 to 165
Boiling point
166 °C
Solubility
SOL IN WATER /TYRAMINE HYDROCHLORIDE/
HS code
292229
Category
Central nervous system drugs
Illustrative photo, drums, an IBC tote and sacks in a chemical warehouse in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Tyramine?

Plain description, key identifiers and synonyms

Tyramine is a primary amino compound obtained by formal decarboxylation of the amino acid tyrosine. It has a role as a neurotransmitter, an EC 3.1.1.8 (cholinesterase) inhibitor, a mouse metabolite, an Escherichia coli metabolite and a human metabolite. It is a monoamine molecular messenger, a member of tyramines and a primary amino compound. It is a conjugate base of a tyraminium.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
4-(2-aminoethyl)phenol
CAS number
51-67-2 CAS number cross-checked
EC number
200-115-8
Molecular formula
C8H11NO
UNII
X8ZC7V0OX3
MDL number
MFCD00008193
InChIKey
DZGWFCGJZKJUFP-UHFFFAOYSA-N
InChI
InChI=1S/C8H11NO/c9-6-5-7-1-3-8(10)4-2-7/h1-4,10H,5-6,9H2
SMILES (canonical and isomeric)
C1=CC(=CC=C1CCN)O

Synonyms

  • 4-(2-Aminoethyl)phenol
  • Uteramine
  • 2-(4-Hydroxyphenyl)ethylamine
  • Tyrosamine
  • Tocosine
  • 4-Hydroxyphenethylamine
  • Systogene
  • Tyramin
  • 4-Hydroxyphenylethylamine
  • Phenol, 4-(2-aminoethyl)-
  • p-(2-Aminoethyl)phenol
  • p-Hydroxyphenethylamine
  • Tenosin-wirkstoff
  • p-Hydroxyphenylethylamine
  • 2-(p-Hydroxyphenyl)ethylamine
  • p-beta-Aminoethylphenol
  • Benzeneethanamine, 4-hydroxy-
  • beta-Hydroxyphenylethylamine
  • alpha-(4-Hydroxyphenyl)-beta-aminoethane
  • 2-p-hydroxyphenylethylamine
  • 4-Hydroxy-beta-phenylethylamine
  • beta-(4-Hydroxyphenyl)ethylamine
  • 4 Hydroxyphenethylamine
  • Tyramine base
  • Phenethylamine, p-hydroxy-
Show all 34 synonyms
  • Phenol, p-(2-aminoethyl)-
  • 4-(2-aminoethyl)-Phenol
  • p-Hydroxy-beta-phenethylamine
  • 2-(4'-Hydroxyphenyl)ethylamine
  • 4-(2-aminoethyl)-pheno
  • [3H]tyramine
  • [3H]-Tyramine
  • Tyramine, free base
  • L-Tyramine

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystals from benzene or alcoholexp.
Melting point
164 to 165exp.
Boiling point
166 °Cexp.
Solubility
SOL IN WATER /TYRAMINE HYDROCHLORIDE/exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
137.18 g/molcalc.
Exact mass
137.0841 Dacalc.
LogP (octanol/water)
0.89calc.
Topological polar surface area
46.25 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
2calc.
Heavy atoms
10calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.25calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Tyramine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 105 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

105 suppliers in 17 countries

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Tyramine price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Phenethylamines are important precursors of isoquinoline alkaloids and important neuroamines (dopamine and tyramine).

Industries and functions

Pharmacological actions

  • Adrenergic Uptake Inhibitors
  • Sympathomimetics

Roles

  • Escherichia coli metabolite
  • animal metabolite
  • antidyskinesia agent
  • antiparkinson drug
  • bacterial metabolite
  • cardiovascular drug
  • enzyme inhibitor
  • eukaryotic metabolite
  • human metabolite
  • mammalian metabolite
  • metabolite
  • molecular messenger
  • mouse metabolite
  • neurotransmitter
  • pharmaceutical
  • prokaryotic metabolite
  • vasoconstrictor agent

Functional uses

  • Flavouring and nutrient

How it is made

Decarboxylation of tyrosine

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Tyramine is traded under.

HS 2922.29Indicative HS code

Amino-naphthols and other amino-phenols, other than those containing more than one kind…

World exports in 2024
$467M
−15.3% vs 2023, imports $454M
2019 to 2024
Top exporters
  1. China63.1%
  2. India * partner reported15.5%
  3. Japan4.0%
Top importers
  1. India * partner reported25.8%
  2. United States14.4%
  3. South Korea7.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Tyramine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Tyramine, based on the data on this page

What is Tyramine?

Tyramine is a primary amino compound obtained by formal decarboxylation of the amino acid tyrosine. It has a role as a neurotransmitter, an EC 3.1.1.8 (cholinesterase) inhibitor, a mouse metabolite, an Escherichia coli metabolite and a human metabolite.

What is the CAS number of Tyramine?

The CAS registry number of Tyramine is 51-67-2.

What is the molecular formula and weight of Tyramine?

The molecular formula of Tyramine is C8H11NO and its molar mass is 137.18 g/mol.

What is Tyramine used for?

Phenethylamines are important precursors of isoquinoline alkaloids and important neuroamines (dopamine and tyramine).

Is Tyramine hazardous?

Tyramine carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Tyramine?

Tyramine is usually classified under HS code 292229 (Amino-naphthols and other amino-phenols, other than those containing more than one kind…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Tyramine?

CompoundList lists 105 suppliers of Tyramine in China, United States, Germany, United Kingdom and 13 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Tyramine in India?

1 supplier in India list Tyramine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Tyramine?

Suppliers quote Tyramine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Tyramine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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