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Skin conditioning agents and actives

Zerumbone

Also known as (2E,6E,10E)-2,6,9,9-tetramethylcycloundeca-2,6,10-trien-1-one, (E,E,E)-2,6,9,9-Tetramethyl-2,6,10-cycloundecatrien-1-one, 2,6,10-Cycloundecatrien-1-one, 2,6,9,9-tetramethyl-, (E,E,E)-

CAS 471-05-6Formula C15H22OMolar mass 218.34 g/molEC 687-304-2
GHS signal word: Warning. Pictograms: Harmful or irritant, Hazardous to the environment 8 suppliers listed
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Zerumbone chemical structure, C15H22O, CAS 471-05-6
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
471-05-6
Formula
C15H22O
Molar mass
218.34 g/mol
EC number
687-304-2
HS code
291429
Category
Skin conditioning agents and actives

What is Zerumbone?

Plain description, key identifiers and synonyms

Zerumbone is a sesquiterpenoid and cyclic ketone that is (1E,4E,8E)-alpha-humulene which is substituted by an oxo group at the carbon atom attached to two double bonds. It is obtained by steam distillation from a type of edible ginger, Zingiber zerumbet Smith, grown particularly in southeast Asia. It has a role as a glioma-associated oncogene inhibitor, an anti-inflammatory agent and a plant metabolite. It is a sesquiterpenoid and a cyclic ketone. It derives from a hydride of an alpha-humulene.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2E,6E,10E)-2,6,9,9-tetramethylcycloundeca-2,6,10-trien-1-one
CAS number
471-05-6
EC number
687-304-2
Molecular formula
C15H22O
MDL number
MFCD03700769
INCI name
ZERUMBONE
InChIKey
GIHNTRQPEMKFKO-SKTNYSRSSA-N
InChI
InChI=1S/C15H22O/c1-12-6-5-7-13(2)14(16)9-11-15(3,4)10-8-12/h7-9,11H,5-6,10H2,1-4H3/b11-9+,12-8+,13-7+
Canonical SMILES
CC1=CCC(C)(C)C=CC(=O)C(C)=CCC1
Isomeric SMILES
C/C/1=C\CC(/C=C/C(=O)/C(=C/CC1)/C)(C)C

Synonyms

  • (2E,6E,10E)-2,6,9,9-tetramethylcycloundeca-2,6,10-trien-1-one
  • (E,E,E)-2,6,9,9-Tetramethyl-2,6,10-cycloundecatrien-1-one
  • 2,6,10-Cycloundecatrien-1-one, 2,6,9,9-tetramethyl-, (E,E,E)-
  • 2E,6E,9E-humulatrien-8-one
  • (2E,6E,10E)-2,6,9,9-Tetramethylcycloundeca-2,6,10-trienone
  • erumbone
  • Zerumbone (Standard)
  • 2,6,9,9-tetramethylcycloundeca-2,6,10-trien-1-one
  • Zerumbone, >=98% (HPLC)
  • (2E,6E,10E)-2,6,9,9-Tetramethyl-2,6,10-cycloundecatrien-1-one

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
218.34 g/molcalc.
Exact mass
218.1671 Dacalc.
LogP (octanol/water)
4.21calc.
Topological polar surface area
17.07 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
0calc.
Heavy atoms
16calc.
Rings
1calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.53calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1C=CCCC=CCCC=C1

O=C1C=CCCC=CCCC=C1

1 ring, 12 atoms.

6 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H317May cause an allergic skin reaction.
  • H400Very toxic to aquatic life.
Precautionary statements (10)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Zerumbone suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 8 suppliers
8 of 8 offers
  • qualityphytochemicals.com
    Unclaimed profile
    ZerumboneGrade, purity and minimum order on request
    Price on request
    View
  • Acorn PharmaTech, LLC
    United States, Redwood CityUnclaimed profile
    ZerumboneGrade, purity and minimum order on request
    Price on request
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  • BioCrick
    China, ChengduUnclaimed profile
    ZerumboneGrade, purity and minimum order on request
    Price on request
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  • Chemenu. Inc.
    China, ShanghaiUnclaimed profile
    ZerumboneGrade, purity and minimum order on request
    Price on request
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  • Glixx Labs, Inc
    United States, HopkintonUnclaimed profile
    ZerumboneGrade, purity and minimum order on request
    Price on request
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  • Hello Bio
    United Kingdom, AvonmouthUnclaimed profile
    ZerumboneGrade, purity and minimum order on request
    Price on request
    View
  • LKT Laboratories, Inc.
    United States, St. PaulUnclaimed profile
    ZerumboneGrade, purity and minimum order on request
    Price on request
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  • Sriramchem
    India, MysuruUnclaimed profile
    ZerumboneGrade, purity and minimum order on request
    Price on request
    View

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

8 suppliers in 4 countries

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Zerumbone price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Cosmetic ingredient, INCI name ZERUMBONE(skin conditioning)

Roles

  • anti-inflammatory agent
  • eukaryotic metabolite
  • glioma-associated oncogene inhibitor
  • metabolite
  • plant metabolite

Cosmetic functions

  • Skin conditioning

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Zerumbone is traded under.

HS 2914.29Indicative HS code

Cyclanic, cyclenic or cycloterpenic ketones without other oxygen function, other

World exports in 2024
$1B
+6.6% vs 2023, imports $980M
2019 to 2024
Top exporters
  1. China32.5%
  2. India * partner reported12.9%
  3. Germany12.3%
Top importers
  1. United States15.7%
  2. Japan8.7%
  3. Germany8.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Zerumbone is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Zerumbone, based on the data on this page

What is Zerumbone?

Zerumbone is a sesquiterpenoid and cyclic ketone that is (1E,4E,8E)-alpha-humulene which is substituted by an oxo group at the carbon atom attached to two double bonds. It is obtained by steam distillation from a type of edible ginger, Zingiber zerumbet Smith, grown particularly in southeast Asia.

What is the CAS number of Zerumbone?

The CAS registry number of Zerumbone is 471-05-6.

What is the molecular formula and weight of Zerumbone?

The molecular formula of Zerumbone is C15H22O and its molar mass is 218.34 g/mol.

What is Zerumbone used for?

Known uses and roles of Zerumbone include skin conditioning agents in cosmetics and personal care, anti-inflammatory agent, eukaryotic metabolite, glioma-associated oncogene inhibitor, metabolite and 2 more.

Is Zerumbone hazardous?

Zerumbone carries the GHS signal word "Warning". Main hazards: may cause an allergic skin reaction, very toxic to aquatic life. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Zerumbone?

Zerumbone is usually classified under HS code 291429 (Cyclanic, cyclenic or cycloterpenic ketones without other oxygen function, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Zerumbone?

CompoundList lists 8 suppliers of Zerumbone in United States, China, United Kingdom and India. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Zerumbone in India?

1 supplier in India list Zerumbone on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Zerumbone?

Suppliers quote Zerumbone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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