CompoundList

Germacrone

Also known as Germacron, (E,E)-Germacrone, 3,7-Cyclodecadien-1-one, 3,7-dimethyl-10-(1-methylethylidene)-, (E,E)-

Germacrone chemical structure, C15H22O, CAS 6902-91-6
2D chemical structure

Key facts

What buyers check first

CAS number
6902-91-6
Formula
C15H22O
Molar mass
218.34 g/mol
EC number
834-535-3
HS code
291429
Category
Insecticides and acaricides

What is Germacrone?

Plain description, key identifiers and synonyms

(E,E)-germacrone is a germacrane sesquiterpenoid that has formula C15H22O. It is a natural product found in traditional medicinal plants of the family Zingiberaceae. The compound exhibits a range of pharmacological activities including anti-inflammatory, anticancer, antiviral, anti-androgenic, antioxidant, antimicrobial, antifungal, neuroprotective and insecticidal activities. It has a role as an autophagy inducer, an antifeedant, an antioxidant, an antiviral agent, an insecticide, a volatile oil component, an antimicrobial agent, an androgen antagonist, an antineoplastic agent, an antifungal agent, an antitussive, a hepatoprotective agent, a neuroprotective agent, an anti-inflammatory agent, an apoptosis inducer and a plant metabolite. It is a germacrane sesquiterpenoid and an olefinic compound.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(3E,7E)-3,7-dimethyl-10-propan-2-ylidenecyclodeca-3,7-dien-1-one
CAS number
6902-91-6
EC number
834-535-3
Molecular formula
C15H22O
UNII
E2WQ6N4FBP
MDL number
MFCD00210050
InChIKey
CAULGCQHVOVVRN-SWZPTJTJSA-N
InChI
InChI=1S/C15H22O/c1-11(2)14-9-8-12(3)6-5-7-13(4)10-15(14)16/h7-8H,5-6,9-10H2,1-4H3/b12-8+,13-7+
Canonical SMILES
CC1=CCC(=C(C)C)C(=O)CC(C)=CCC1
Isomeric SMILES
C/C/1=C\CC(=C(C)C)C(=O)C/C(=C/CC1)/C

Synonyms

  • Germacron
  • (E,E)-Germacrone
  • 3,7-Cyclodecadien-1-one, 3,7-dimethyl-10-(1-methylethylidene)-, (E,E)-
  • (3E,7E)-3,7-Dimethyl-10-(1-methylethylidene)-3,7-cyclodecadien-1-one
  • (3E,7E)-3,7-Dimethyl-10-(propan-2-ylidene)cyclodeca-3,7-dienone
  • Germacrone (>90%)
  • (3E,7E)-3,7-Dimethyl-10-(propan-2-ylidene)cyclodeca-3,7-dien-1-one
  • (3E,7E)-3,7-dimethyl-10-propan-2-ylidenecyclodeca-3,7-dien-1-one
  • (E,E)-Germacra-3,7(11),9-trien-6-one
  • germecrone
  • germacrone [M+H]+
  • trans,trans-germacrone
  • Germacrone (Standard)
  • Germacrone, analytical standard
  • (3E,7E)-3,7-Dimethyl-10-(propan-2-ylidene)cyclodec
  • 3,7-Cyclodecadien-1-one, 3,7-dimethyl-10-(1-methylethylidene)-
  • trans,trans-3,7-dimethyl-10-isopropylidene-3,7-cyclodecadien-1-one
  • (3E,7E)-3,7-dimethyl-10-propan-2-ylidene-cyclodeca-3,7-dien-1-one

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
218.34 g/molcalc.
Exact mass
218.1671 Dacalc.
LogP (octanol/water)
4.36calc.
Topological polar surface area
17.07 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
0calc.
Heavy atoms
16calc.
Rings
1calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.53calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C=C1CC=CCCC=CCC1=O

C=C1CC=CCCC=CCC1=O

1 ring, 12 atoms.

8 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
Precautionary statements (9)
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Germacrone suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 6 suppliers
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Where suppliers are based

6 suppliers in 2 countries

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Germacrone price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • androgen antagonist
  • antagonist
  • anti-inflammatory agent
  • antifeedant
  • antifungal agent
  • antimicrobial agent
  • antineoplastic agent
  • antioxidant
  • antitussive
  • antiviral agent
  • apoptosis inducer
  • autophagy inducer
  • hepatoprotective agent
  • hormone antagonist
  • hormone receptor modulator
  • insecticide
  • metabolite
  • neuroprotective agent
  • pesticide
  • pharmaceutical
  • plant metabolite
  • protective agent
  • receptor modulator
  • volatile oil component

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Germacrone is traded under.

HS 2914.29Indicative HS code

Cyclanic, cyclenic or cycloterpenic ketones without other oxygen function, other

World exports in 2024
$1B
+6.6% vs 2023, imports $980M
2019 to 2024
Top exporters
  1. China32.5%
  2. India * partner reported12.9%
  3. Germany12.3%
Top importers
  1. United States15.7%
  2. Japan8.7%
  3. Germany8.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Germacrone is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Germacrone, based on the data on this page

What is Germacrone?

(E,E)-germacrone is a germacrane sesquiterpenoid that has formula C15H22O. It is a natural product found in traditional medicinal plants of the family Zingiberaceae.

What is the CAS number of Germacrone?

The CAS registry number of Germacrone is 6902-91-6.

What is the molecular formula and weight of Germacrone?

The molecular formula of Germacrone is C15H22O and its molar mass is 218.34 g/mol.

What is Germacrone used for?

Known uses and roles of Germacrone include insecticides in agriculture and crop protection, aldehydes and ketones in flavors and fragrances, androgen antagonist, antagonist, anti-inflammatory agent and 21 more.

Is Germacrone hazardous?

Germacrone carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Germacrone?

Germacrone is usually classified under HS code 291429 (Cyclanic, cyclenic or cycloterpenic ketones without other oxygen function, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Germacrone?

CompoundList lists 6 suppliers of Germacrone in China and United States. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Germacrone?

Suppliers quote Germacrone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Germacrone

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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