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Murcko scaffold

Ring system with 3 rings and 25 atoms

139 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
139
With full pages
37
Scaffold SMILES

O=C(Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 139 chemicals

2-Bromo-3,4,5-trimethoxy-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]benzamide chemical structure, C20H19BrN4O6S, CAS 307540-34-7
2-Bromo-3,4,5-trimethoxy-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]benzamide
CAS 307540-34-7C20H19BrN4O6S
4-tert-Butyl-N-[4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl]benzamide chemical structure, C23H26N4O3S, CAS 321965-52-0
4-tert-Butyl-N-[4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl]benzamide
CAS 321965-52-0C23H26N4O3S
3-Chloro-N-[4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl]benzamide chemical structure, C19H17ClN4O3S, CAS 443732-27-2
3-Chloro-N-[4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl]benzamide
CAS 443732-27-2C19H17ClN4O3S
2,4-Dichloro-N-{4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl}benzamide chemical structure, C19H16Cl2N4O3S, CAS 289630-01-9
2,4-Dichloro-N-{4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl}benzamide
CAS 289630-01-9C19H16Cl2N4O3S
N-(4-{[(4,6-Dimethyl-2-pyrimidinyl)amino]sulfonyl}phenyl)-3,5-dimethoxybenzamide chemical structure, C21H22N4O5S, CAS 307509-39-3
N-(4-{[(4,6-Dimethyl-2-pyrimidinyl)amino]sulfonyl}phenyl)-3,5-dimethoxybenzamide
CAS 307509-39-3C21H22N4O5S
2-Chloro-N-(4-{[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl}phenyl)benzamide chemical structure, C19H17ClN4O3S, CAS 261704-13-6
2-Chloro-N-(4-{[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl}phenyl)benzamide
CAS 261704-13-6C19H17ClN4O3S
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-3-methylbenzamide chemical structure, C20H20N4O3S, CAS 313261-56-2
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-3-methylbenzamide
CAS 313261-56-2C20H20N4O3S
2,5-Dichloro-N-{4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl}benzamide chemical structure, C19H16Cl2N4O3S, CAS 302951-66-2
2,5-Dichloro-N-{4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl}benzamide
CAS 302951-66-2C19H16Cl2N4O3S
N-(4-{[(4,6-Dimethyl-2-pyrimidinyl)amino]sulfonyl}phenyl)-4-methoxybenzamide chemical structure, C20H20N4O4S, CAS 112865-30-2
N-(4-{[(4,6-Dimethyl-2-pyrimidinyl)amino]sulfonyl}phenyl)-4-methoxybenzamide
CAS 112865-30-2C20H20N4O4S
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-2-methylbenzamide chemical structure, C20H20N4O3S, CAS 289630-05-3
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-2-methylbenzamide
CAS 289630-05-3C20H20N4O3S
3-Bromo-N-{4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-4-methylbenzamide chemical structure, C20H19BrN4O3S, CAS 443668-66-4
3-Bromo-N-{4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-4-methylbenzamide
CAS 443668-66-4C20H19BrN4O3S
AG-690/36598014 chemical structure, C18H14Cl2N4O3S, CAS 5266-46-6
AG-690/36598014
CAS 5266-46-6C18H14Cl2N4O3S
N-[4-(4,6-Dimethyl-pyrimidin-2-ylsulfamoyl)-phenyl]-3,4-dimethoxy-benzamide chemical structure, C21H22N4O5S, CAS 307505-08-4
N-[4-(4,6-Dimethyl-pyrimidin-2-ylsulfamoyl)-phenyl]-3,4-dimethoxy-benzamide
CAS 307505-08-4C21H22N4O5S
N-[4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl]-3,4-dimethylbenzamide chemical structure, C21H22N4O3S, CAS 333747-30-1
N-[4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl]-3,4-dimethylbenzamide
CAS 333747-30-1C21H22N4O3S
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-4-methylbenzamide chemical structure, C20H20N4O3S, CAS 110534-79-7
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-4-methylbenzamide
CAS 110534-79-7C20H20N4O3S
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-3-methoxybenzamide chemical structure, C20H20N4O4S, CAS 113012-37-6
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-3-methoxybenzamide
CAS 113012-37-6C20H20N4O4S
2-(((4-(((4,6-Dimethyl-2-pyrimidinyl)amino)sulphonyl)phenyl)amino)carbonyl)benzoic acid chemical structure, C20H18N4O5S, CAS 94134-30-2
2-(((4-(((4,6-Dimethyl-2-pyrimidinyl)amino)sulphonyl)phenyl)amino)carbonyl)benzoic acid
CAS 94134-30-2C20H18N4O5S
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-2-iodobenzamide chemical structure, C19H17IN4O3S, CAS 313952-70-4
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-2-iodobenzamide
CAS 313952-70-4C19H17IN4O3S
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-3-iodobenzamide chemical structure, C19H17IN4O3S, CAS 385405-84-5
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-3-iodobenzamide
CAS 385405-84-5C19H17IN4O3S
N-(4-{[(4,6-Dimethyl-2-pyrimidinyl)amino]sulfonyl}phenyl)-4-ethoxybenzamide chemical structure, C21H22N4O4S, CAS 314247-83-1
N-(4-{[(4,6-Dimethyl-2-pyrimidinyl)amino]sulfonyl}phenyl)-4-ethoxybenzamide
CAS 314247-83-1C21H22N4O4S
3,4-Dimethoxy-N-[4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl]benzamide chemical structure, C20H20N4O5S, CAS 346719-27-5
3,4-Dimethoxy-N-[4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl]benzamide
CAS 346719-27-5C20H20N4O5S
3,5-Dimethoxy-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]benzamide chemical structure, C19H18N4O5S, CAS 444068-77-3
3,5-Dimethoxy-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]benzamide
CAS 444068-77-3C19H18N4O5S
N-[4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl]-2,4-dimethoxybenzamide chemical structure, C21H22N4O5S, CAS 303797-85-5
N-[4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl]-2,4-dimethoxybenzamide
CAS 303797-85-5C21H22N4O5S
3-Chloro-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]benzamide chemical structure, C17H13ClN4O3S, CAS 307540-25-6
3-Chloro-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]benzamide
CAS 307540-25-6C17H13ClN4O3S