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Murcko scaffold

Ring system with 3 rings and 22 atoms

98 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
98
With full pages
12
Scaffold SMILES

C(=Cc1ccc(C=Cc2ccccc2)cc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(=Cc1ccc(C=Cc2ccccc2)cc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 98 chemicals

Bis-MSB chemical structure, C24H22, CAS 13280-61-0
Bis-MSB
CAS 13280-61-0C24H22
4,4'-(1,4-Phenylenedi-2,1-ethenediyl)bis[benzonitrile] chemical structure, C24H16N2, CAS 13001-40-6
4,4'-(1,4-Phenylenedi-2,1-ethenediyl)bis[benzonitrile]
CAS 13001-40-6C24H16N2
Benzene, 1,4-bis[2-(3,4,5-trimethoxyphenyl)ethenyl]- chemical structure, C28H30O6, CAS 23845-73-0
Benzene, 1,4-bis[2-(3,4,5-trimethoxyphenyl)ethenyl]-
CAS 23845-73-0C28H30O6
(2Z,2'Z)-2,2'-(1,4-Phenylene)bis(3-phenylacrylonitrile) chemical structure, C24H16N2, CAS 13707-95-4
(2Z,2'Z)-2,2'-(1,4-Phenylene)bis(3-phenylacrylonitrile)
CAS 13707-95-4C24H16N2
3,3'-(1,4-Phenylene)bis(2-phenylacrylonitrile) chemical structure, C24H16N2, CAS 58393-80-9
3,3'-(1,4-Phenylene)bis(2-phenylacrylonitrile)
CAS 58393-80-9C24H16N2
1,4-Bis[(E)-2-phenylethenyl]benzene chemical structure, C22H18, CAS 1608-41-9
1,4-Bis[(E)-2-phenylethenyl]benzene
CAS 1608-41-9C22H18
Benzene, 1-[(1E)-2-(4-methylphenyl)ethenyl]-4-[(1E)-2-phenylethenyl]- chemical structure, C23H20, CAS 261778-66-9
Benzene, 1-[(1E)-2-(4-methylphenyl)ethenyl]-4-[(1E)-2-phenylethenyl]-
CAS 261778-66-9C23H20
RefChem:854818 chemical structure, C22H18, CAS 1608-40-8
RefChem:854818
CAS 1608-40-8C22H18
Benzene, p-bis(o-methylstyryl)- chemical structure, C24H22, CAS 66726-71-4
Benzene, p-bis(o-methylstyryl)-
CAS 66726-71-4C24H22
4,4'-(p-Phenylenediethene-2,1-diyl)bisbenzonitrile chemical structure, C24H16N2, CAS 58449-88-0
4,4'-(p-Phenylenediethene-2,1-diyl)bisbenzonitrile
CAS 58449-88-0C24H16N2
1-Methyl-4-[(1E)-2-{4-[(1E)-2-phenylethenyl]phenyl}ethenyl]benzene chemical structure, C23H20
1-Methyl-4-[(1E)-2-{4-[(1E)-2-phenylethenyl]phenyl}ethenyl]benzene
C23H20
1,4-Bis(4-methylstyryl)benzene chemical structure, C24H22, CAS 76439-00-4
1,4-Bis(4-methylstyryl)benzene
CAS 76439-00-4C24H22
1,4-Bis(2-(4-chloro-2-methoxyphenyl)vinyl)benzene chemical structure, C24H20Cl2O2, CAS 84100-88-9
1,4-Bis(2-(4-chloro-2-methoxyphenyl)vinyl)benzene
CAS 84100-88-9C24H20Cl2O2
Benzonitrile, 2,2'-(1,4-phenylenedi-2,1-ethenediyl)bis- chemical structure, C24H16N2, CAS 13001-39-3
Benzonitrile, 2,2'-(1,4-phenylenedi-2,1-ethenediyl)bis-
CAS 13001-39-3C24H16N2
Benzonitrile, 2-[2-[4-[2-(3-cyanophenyl)ethenyl]phenyl]ethenyl]- chemical structure, C24H16N2, CAS 79026-03-2
Benzonitrile, 2-[2-[4-[2-(3-cyanophenyl)ethenyl]phenyl]ethenyl]-
CAS 79026-03-2C24H16N2
5-[(E)-2-[4-[(E)-2-(3-Carboxy-4-hydroxyphenyl)ethenyl]phenyl]ethenyl]-2-hydroxybenzoic acid chemical structure, C24H18O6, CAS 215294-98-7
5-[(E)-2-[4-[(E)-2-(3-Carboxy-4-hydroxyphenyl)ethenyl]phenyl]ethenyl]-2-hydroxybenzoic acid
CAS 215294-98-7C24H18O6
1-Bromo-2,5-bis(3-carboxy-4-hydroxystyryl)benzene chemical structure, C24H17BrO6, CAS 291766-06-8
1-Bromo-2,5-bis(3-carboxy-4-hydroxystyryl)benzene
CAS 291766-06-8C24H17BrO6
5,5'-{1,4-Phenylenedi[(E)-ethene-2,1-diyl]}di(benzene-1,3-diol) chemical structure, C22H18O4, CAS 360784-23-2
5,5'-{1,4-Phenylenedi[(E)-ethene-2,1-diyl]}di(benzene-1,3-diol)
CAS 360784-23-2C22H18O4
1-Fluoro-2,5-bis[(E)-3-carboxy-4-hydroxystyryl]benzene chemical structure, C24H17FO6, CAS 760988-03-2
1-Fluoro-2,5-bis[(E)-3-carboxy-4-hydroxystyryl]benzene
CAS 760988-03-2C24H17FO6
trans,trans-1,4-Bis(2-pentafluorophenylethenyl)benzene chemical structure, C22H8F10
trans,trans-1,4-Bis(2-pentafluorophenylethenyl)benzene
C22H8F10
(E)-1,4-Bis(-4-bromostyryl)benzene chemical structure, C22H16Br2, CAS 58358-55-7
(E)-1,4-Bis(-4-bromostyryl)benzene
CAS 58358-55-7C22H16Br2
4-[(E)-2-[4-[(E)-2-(4-Formyl-2,5-dihexoxyphenyl)ethenyl]-2,5-dihexoxyphenyl]ethenyl]-2,5-dihexoxybenzaldehyde chemical structure, C60H90O8, CAS 349095-04-1
4-[(E)-2-[4-[(E)-2-(4-Formyl-2,5-dihexoxyphenyl)ethenyl]-2,5-dihexoxyphenyl]ethenyl]-2,5-dihexoxybenzaldehyde
CAS 349095-04-1C60H90O8
Methoxy-X04 chemical structure, C23H20O3, CAS 863918-78-9
Methoxy-X04
CAS 863918-78-9C23H20O3
3,3'-(1,4-Phenylenedi-2,1-ethenediyl)bis(benzonitrile) chemical structure, C24H16N2, CAS 36755-00-7
3,3'-(1,4-Phenylenedi-2,1-ethenediyl)bis(benzonitrile)
CAS 36755-00-7C24H16N2