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Murcko scaffold

Ring system with 3 rings and 25 atoms

58 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
58
With full pages
10
Scaffold SMILES

O=C(Nc1ccc(S(=O)(=O)Nc2ccncn2)cc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc(S(=O)(=O)Nc2ccncn2)cc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 58 chemicals

4-Chloro-N-{4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl}benzamide chemical structure, C19H17ClN4O3S, CAS 316128-63-9
4-Chloro-N-{4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl}benzamide
CAS 316128-63-9C19H17ClN4O3S
N-[4-[(2,6-Dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-4-propan-2-ylbenzamide chemical structure, C22H24N4O3S, CAS 560075-72-1
N-[4-[(2,6-Dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-4-propan-2-ylbenzamide
CAS 560075-72-1C22H24N4O3S
N-(4-{[(2,6-Dimethoxy-4-pyrimidinyl)amino]sulfonyl}phenyl)-4-methylbenzamide chemical structure, C20H20N4O5S, CAS 289630-94-0
N-(4-{[(2,6-Dimethoxy-4-pyrimidinyl)amino]sulfonyl}phenyl)-4-methylbenzamide
CAS 289630-94-0C20H20N4O5S
N-[4-[(2,6-Dimethoxypyrimidin-4-yl)sulfamoyl]phenyl]-3-(1,1,2,2-tetrafluoroethoxy)benzamide chemical structure, C21H18F4N4O6S, CAS 444931-19-5
N-[4-[(2,6-Dimethoxypyrimidin-4-yl)sulfamoyl]phenyl]-3-(1,1,2,2-tetrafluoroethoxy)benzamide
CAS 444931-19-5C21H18F4N4O6S
2-Iodo-N-[4-[(6-methoxypyrimidin-4-yl)sulfamoyl]phenyl]benzamide chemical structure, C18H15IN4O4S, CAS 6138-63-2
2-Iodo-N-[4-[(6-methoxypyrimidin-4-yl)sulfamoyl]phenyl]benzamide
CAS 6138-63-2C18H15IN4O4S
N-[4-(2,6-Dimethyl-pyrimidin-4-ylsulfamoyl)-phenyl]-3,4-dimethoxy-benzamide chemical structure, C21H22N4O5S, CAS 307545-08-0
N-[4-(2,6-Dimethyl-pyrimidin-4-ylsulfamoyl)-phenyl]-3,4-dimethoxy-benzamide
CAS 307545-08-0C21H22N4O5S
N-{4-[(2,6-Dimethoxypyrimidin-4-yl)sulfamoyl]phenyl}-3-iodobenzamide chemical structure, C19H17IN4O5S, CAS 385405-85-6
N-{4-[(2,6-Dimethoxypyrimidin-4-yl)sulfamoyl]phenyl}-3-iodobenzamide
CAS 385405-85-6C19H17IN4O5S
N-[4-[(2,6-Dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-4-methoxybenzamide chemical structure, C20H20N4O4S, CAS 316128-64-0
N-[4-[(2,6-Dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-4-methoxybenzamide
CAS 316128-64-0C20H20N4O4S
N-{4-[(2,6-Dimethoxypyrimidin-4-yl)sulfamoyl]phenyl}benzamide chemical structure, C19H18N4O5S, CAS 289630-84-8
N-{4-[(2,6-Dimethoxypyrimidin-4-yl)sulfamoyl]phenyl}benzamide
CAS 289630-84-8C19H18N4O5S
2-Chloro-N-{4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl}benzamide chemical structure, C19H17ClN4O3S, CAS 303124-63-2
2-Chloro-N-{4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl}benzamide
CAS 303124-63-2C19H17ClN4O3S
N-{4-[(2,6-Dimethoxypyrimidin-4-yl)sulfamoyl]phenyl}-3,4-dimethoxybenzamide chemical structure, C21H22N4O7S, CAS 307505-09-5
N-{4-[(2,6-Dimethoxypyrimidin-4-yl)sulfamoyl]phenyl}-3,4-dimethoxybenzamide
CAS 307505-09-5C21H22N4O7S
N-{4-[(2,6-Dimethoxypyrimidin-4-yl)sulfamoyl]phenyl}-2,4-dimethoxybenzamide chemical structure, C21H22N4O7S, CAS 300818-52-4
N-{4-[(2,6-Dimethoxypyrimidin-4-yl)sulfamoyl]phenyl}-2,4-dimethoxybenzamide
CAS 300818-52-4C21H22N4O7S
3-Chloro-N-{4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl}benzamide chemical structure, C19H17ClN4O3S, CAS 307545-07-9
3-Chloro-N-{4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl}benzamide
CAS 307545-07-9C19H17ClN4O3S
4-Bromo-N-{4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl}benzamide chemical structure, C19H17BrN4O3S, CAS 303124-71-2
4-Bromo-N-{4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl}benzamide
CAS 303124-71-2C19H17BrN4O3S
N-(4-(N-(2,6-Dimethoxypyrimidin-4-yl)sulfamoyl)phenyl)-3,4-dimethylbenzamide chemical structure, C21H22N4O5S, CAS 333747-31-2
N-(4-(N-(2,6-Dimethoxypyrimidin-4-yl)sulfamoyl)phenyl)-3,4-dimethylbenzamide
CAS 333747-31-2C21H22N4O5S
N-{4-[(2,6-Dimethylpyrimidin-4-yl)sulfamoyl]phenyl}-3-methoxybenzamide chemical structure, C20H20N4O4S, CAS 442567-00-2
N-{4-[(2,6-Dimethylpyrimidin-4-yl)sulfamoyl]phenyl}-3-methoxybenzamide
CAS 442567-00-2C20H20N4O4S
N-{4-[(2,6-Dimethoxypyrimidin-4-yl)sulfamoyl]phenyl}-3-fluorobenzamide chemical structure, C19H17FN4O5S, CAS 441316-13-8
N-{4-[(2,6-Dimethoxypyrimidin-4-yl)sulfamoyl]phenyl}-3-fluorobenzamide
CAS 441316-13-8C19H17FN4O5S
3,4-Dichloro-N-{4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl}benzamide chemical structure, C19H16Cl2N4O3S, CAS 329225-98-1
3,4-Dichloro-N-{4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl}benzamide
CAS 329225-98-1C19H16Cl2N4O3S
N-{4-[(2,6-Dimethoxypyrimidin-4-yl)sulfamoyl]phenyl}-4-(propan-2-yloxy)benzamide chemical structure, C22H24N4O6S, CAS 431913-20-1
N-{4-[(2,6-Dimethoxypyrimidin-4-yl)sulfamoyl]phenyl}-4-(propan-2-yloxy)benzamide
CAS 431913-20-1C22H24N4O6S
4-Ethoxy-N-(4-(N-(6-methoxypyrimidin-4-yl)sulfamoyl)phenyl)benzamide chemical structure, C20H20N4O5S, CAS 302951-53-7
4-Ethoxy-N-(4-(N-(6-methoxypyrimidin-4-yl)sulfamoyl)phenyl)benzamide
CAS 302951-53-7C20H20N4O5S
2,5-Dichloro-N-{4-[(2,6-dimethoxypyrimidin-4-yl)sulfamoyl]phenyl}benzamide chemical structure, C19H16Cl2N4O5S, CAS 302951-67-3
2,5-Dichloro-N-{4-[(2,6-dimethoxypyrimidin-4-yl)sulfamoyl]phenyl}benzamide
CAS 302951-67-3C19H16Cl2N4O5S
2,5-Dichloro-N-(4-(N-(6-methoxypyrimidin-4-yl)sulfamoyl)phenyl)benzamide chemical structure, C18H14Cl2N4O4S, CAS 302951-68-4
2,5-Dichloro-N-(4-(N-(6-methoxypyrimidin-4-yl)sulfamoyl)phenyl)benzamide
CAS 302951-68-4C18H14Cl2N4O4S
N-{4-[(2,6-Dimethoxypyrimidin-4-yl)sulfamoyl]phenyl}-2,6-difluorobenzamide chemical structure, C19H16F2N4O5S, CAS 302951-75-3
N-{4-[(2,6-Dimethoxypyrimidin-4-yl)sulfamoyl]phenyl}-2,6-difluorobenzamide
CAS 302951-75-3C19H16F2N4O5S
3-Chloro-N-(4-(N-(6-methoxypyrimidin-4-yl)sulfamoyl)phenyl)benzamide chemical structure, C18H15ClN4O4S, CAS 302952-06-3
3-Chloro-N-(4-(N-(6-methoxypyrimidin-4-yl)sulfamoyl)phenyl)benzamide
CAS 302952-06-3C18H15ClN4O4S