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Murcko scaffold

AC1Lgqzx scaffold

22 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
22
With full pages
6
Scaffold SMILES

O=C(CSc1ccccc1)N1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the AC1Lgqzx page
Murcko scaffold O=C(CSc1ccccc1)N1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

2-[(2-Oxo-2-piperidin-1-ylethyl)thio]benzoic acid chemical structure, C14H17NO3S, CAS 354128-84-0
2-[(2-Oxo-2-piperidin-1-ylethyl)thio]benzoic acid
CAS 354128-84-0C14H17NO3S
2-(4-Chlorophenyl)sulfanyl-1-(4-methylpiperidin-1-yl)ethanone chemical structure, C14H18ClNOS, CAS 333741-58-5
2-(4-Chlorophenyl)sulfanyl-1-(4-methylpiperidin-1-yl)ethanone
CAS 333741-58-5C14H18ClNOS
2-(4-Chlorophenyl)sulfanyl-1-piperidin-1-ylethanone chemical structure, C13H16ClNOS, CAS 92020-87-6
2-(4-Chlorophenyl)sulfanyl-1-piperidin-1-ylethanone
CAS 92020-87-6C13H16ClNOS
AC1Lgqzx chemical structure, C13H17NOS, CAS 15911-04-3
AC1Lgqzx
CAS 15911-04-3C13H17NOS
1-{[(4-Methylphenyl)sulfanyl]acetyl}piperidine chemical structure, C14H19NOS, CAS 156001-91-1
1-{[(4-Methylphenyl)sulfanyl]acetyl}piperidine
CAS 156001-91-1C14H19NOS
2-(4-Bromophenyl)sulfanyl-1-(4-methylpiperidin-1-yl)ethanone chemical structure, C14H18BrNOS, CAS 709003-34-9
2-(4-Bromophenyl)sulfanyl-1-(4-methylpiperidin-1-yl)ethanone
CAS 709003-34-9C14H18BrNOS
Methyl 1-[(phenylthio)acetyl]-4-piperidinecarboxylate chemical structure, C15H19NO3S, CAS 432500-82-8
Methyl 1-[(phenylthio)acetyl]-4-piperidinecarboxylate
CAS 432500-82-8C15H19NO3S
1-[2-(4-Methylphenyl)sulfanylpropanoyl]piperidine-4-carboxamide chemical structure, C16H22N2O2S, CAS 680601-00-7
1-[2-(4-Methylphenyl)sulfanylpropanoyl]piperidine-4-carboxamide
CAS 680601-00-7C16H22N2O2S
1-(3,5-Dimethylpiperidin-1-yl)-2-(4-methylphenyl)sulfanylethanone chemical structure, C16H23NOS, CAS 701225-33-4
1-(3,5-Dimethylpiperidin-1-yl)-2-(4-methylphenyl)sulfanylethanone
CAS 701225-33-4C16H23NOS
Ethyl 1-{[(4-methylphenyl)sulfanyl]acetyl}piperidine-3-carboxylate chemical structure, C17H23NO3S, CAS 701241-92-1
Ethyl 1-{[(4-methylphenyl)sulfanyl]acetyl}piperidine-3-carboxylate
CAS 701241-92-1C17H23NO3S
2-((4-Chlorophenyl)thio)-1-(3,5-dimethylpiperidin-1-yl)ethan-1-one chemical structure, C15H20ClNOS, CAS 892061-36-8
2-((4-Chlorophenyl)thio)-1-(3,5-dimethylpiperidin-1-yl)ethan-1-one
CAS 892061-36-8C15H20ClNOS
2-[(4-Bromophenyl)thio]-1-(2-ethyl-1-piperidinyl)ethanone chemical structure, C15H20BrNOS, CAS 380491-74-7
2-[(4-Bromophenyl)thio]-1-(2-ethyl-1-piperidinyl)ethanone
CAS 380491-74-7C15H20BrNOS
2-[(4-Methylphenyl)sulfanyl]-1-(3-methylpiperidin-1-yl)propan-1-one chemical structure, C16H23NOS, CAS 928904-21-6
2-[(4-Methylphenyl)sulfanyl]-1-(3-methylpiperidin-1-yl)propan-1-one
CAS 928904-21-6C16H23NOS
2-[(4-Chlorophenyl)sulfanyl]-1-(3-methylpiperidin-1-yl)ethanone chemical structure, C14H18ClNOS, CAS 928958-29-6
2-[(4-Chlorophenyl)sulfanyl]-1-(3-methylpiperidin-1-yl)ethanone
CAS 928958-29-6C14H18ClNOS
1-{2-[(4-Chlorophenyl)sulfanyl]butanoyl}piperidine-4-carboxamide chemical structure, C16H21ClN2O2S, CAS 1158740-56-7
1-{2-[(4-Chlorophenyl)sulfanyl]butanoyl}piperidine-4-carboxamide
CAS 1158740-56-7C16H21ClN2O2S
1-{2-[(4-Fluorophenyl)sulfanyl]acetyl}piperidine-4-carbonitrile chemical structure, C14H15FN2OS, CAS 2327283-05-4
1-{2-[(4-Fluorophenyl)sulfanyl]acetyl}piperidine-4-carbonitrile
CAS 2327283-05-4C14H15FN2OS
1-[2-(4-Chlorophenyl)sulfanylacetyl]-N-[2-[2-(dimethylamino)ethyldisulfanyl]ethyl]piperidine-4-carboxamide chemical structure, C20H30ClN3O2S3, CAS 1469338-01-9
1-[2-(4-Chlorophenyl)sulfanylacetyl]-N-[2-[2-(dimethylamino)ethyldisulfanyl]ethyl]piperidine-4-carboxamide
CAS 1469338-01-9C20H30ClN3O2S3
6H05 trifluoroacetate chemical structure, C22H31ClF3N3O4S3, CAS 2061344-88-3
6H05 trifluoroacetate
CAS 2061344-88-3C22H31ClF3N3O4S3
2-((4-Fluorophenyl)thio)-1-(4-(methylsulfonyl)piperidin-1-yl)ethanone chemical structure, C14H18FNO3S2, CAS 1705405-52-2
2-((4-Fluorophenyl)thio)-1-(4-(methylsulfonyl)piperidin-1-yl)ethanone
CAS 1705405-52-2C14H18FNO3S2
1-(4-Amino-4-ethylpiperidin-1-yl)-2-(phenylsulfanyl)butan-1-one hydrochloride chemical structure, C17H27ClN2OS, CAS 2418668-22-9
1-(4-Amino-4-ethylpiperidin-1-yl)-2-(phenylsulfanyl)butan-1-one hydrochloride
CAS 2418668-22-9C17H27ClN2OS
1-(4-Azidopiperidin-1-yl)-2-[(4-fluorophenyl)sulfanyl]ethan-1-one chemical structure, C13H15FN4OS, CAS 3054612-47-1
1-(4-Azidopiperidin-1-yl)-2-[(4-fluorophenyl)sulfanyl]ethan-1-one
CAS 3054612-47-1C13H15FN4OS
2-((4-Chlorophenyl)thio)-1-(4,4-dimethylpiperidin-1-yl)ethan-1-one chemical structure, C15H20ClNOS, CAS 2785481-76-5
2-((4-Chlorophenyl)thio)-1-(4,4-dimethylpiperidin-1-yl)ethan-1-one
CAS 2785481-76-5C15H20ClNOS