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Murcko scaffold

Ring system with 4 rings and 22 atoms

11 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
11
With full pages
3
Scaffold SMILES

O=C(c1cn2cc(-c3ccccc3)nc2s1)N1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1cn2cc(-c3ccccc3)nc2s1)N1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

Ethyl 1-(3-methyl-6-phenylimidazo[2,1-b]thiazole-2-carbonyl)piperidine-4-carboxylate chemical structure, C21H23N3O3S, CAS 852132-53-7
Ethyl 1-(3-methyl-6-phenylimidazo[2,1-b]thiazole-2-carbonyl)piperidine-4-carboxylate
CAS 852132-53-7C21H23N3O3S
Ethyl 1-[6-(4-fluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carbonyl]piperidine-3-carboxylate chemical structure, C21H22FN3O3S, CAS 852133-79-0
Ethyl 1-[6-(4-fluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carbonyl]piperidine-3-carboxylate
CAS 852133-79-0C21H22FN3O3S
Methyl 1-[6-(4-fluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carbonyl]piperidine-4-carboxylate chemical structure, C20H20FN3O3S, CAS 852133-81-4
Methyl 1-[6-(4-fluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carbonyl]piperidine-4-carboxylate
CAS 852133-81-4C20H20FN3O3S
(3-Methyl-6-phenylimidazo[2,1-b]thiazol-2-yl)(piperidin-1-yl)methanone chemical structure, C18H19N3OS, CAS 852132-43-5
(3-Methyl-6-phenylimidazo[2,1-b]thiazol-2-yl)(piperidin-1-yl)methanone
CAS 852132-43-5C18H19N3OS
(6-(4-Fluorophenyl)-3-methylimidazo[2,1-b]thiazol-2-yl)(4-methylpiperidin-1-yl)methanone chemical structure, C19H20FN3OS, CAS 852133-78-9
(6-(4-Fluorophenyl)-3-methylimidazo[2,1-b]thiazol-2-yl)(4-methylpiperidin-1-yl)methanone
CAS 852133-78-9C19H20FN3OS
1-(3-Methyl-6-phenylimidazo[2,1-b]thiazole-2-carbonyl)piperidine-4-carboxamide chemical structure, C19H20N4O2S, CAS 919018-70-5
1-(3-Methyl-6-phenylimidazo[2,1-b]thiazole-2-carbonyl)piperidine-4-carboxamide
CAS 919018-70-5C19H20N4O2S
1-(6-(4-Methoxyphenyl)-3-methylimidazo[2,1-b]thiazole-2-carbonyl)piperidine-4-carboxamide chemical structure, C20H22N4O3S, CAS 852135-14-9
1-(6-(4-Methoxyphenyl)-3-methylimidazo[2,1-b]thiazole-2-carbonyl)piperidine-4-carboxamide
CAS 852135-14-9C20H22N4O3S
Methyl 1-(3-methyl-6-(3-nitrophenyl)imidazo[2,1-b]thiazole-2-carbonyl)piperidine-4-carboxylate chemical structure, C20H20N4O5S, CAS 852135-33-2
Methyl 1-(3-methyl-6-(3-nitrophenyl)imidazo[2,1-b]thiazole-2-carbonyl)piperidine-4-carboxylate
CAS 852135-33-2C20H20N4O5S
Ethyl 1-(3-methyl-6-(3-nitrophenyl)imidazo[2,1-b]thiazole-2-carbonyl)piperidine-3-carboxylate chemical structure, C21H22N4O5S, CAS 852135-31-0
Ethyl 1-(3-methyl-6-(3-nitrophenyl)imidazo[2,1-b]thiazole-2-carbonyl)piperidine-3-carboxylate
CAS 852135-31-0C21H22N4O5S
1-[3-Methyl-6-(3-nitrophenyl)imidazo[2,1-b][1,3]thiazole-2-carbonyl]piperidine-4-carboxamide chemical structure, C19H19N5O4S, CAS 852135-98-9
1-[3-Methyl-6-(3-nitrophenyl)imidazo[2,1-b][1,3]thiazole-2-carbonyl]piperidine-4-carboxamide
CAS 852135-98-9C19H19N5O4S
3-Piperidinecarboxylic acid, 1-[(3-methyl-6-phenylimidazo[2,1-b]thiazol-2-yl)carbonyl]- chemical structure, C19H19N3O3S, CAS 1215655-82-5
3-Piperidinecarboxylic acid, 1-[(3-methyl-6-phenylimidazo[2,1-b]thiazol-2-yl)carbonyl]-
CAS 1215655-82-5C19H19N3O3S