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Murcko scaffold

2-Benzyl-1,3-thiazole scaffold

235 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
235
With full pages
25
Scaffold SMILES

c1ccc(Cc2nccs2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Benzyl-1,3-thiazole page
Murcko scaffold c1ccc(Cc2nccs2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 235 chemicals

2-Benzyl-4-methyl-1,3-thiazole chemical structure, C11H11NS, CAS 7210-74-4
2-Benzyl-4-methyl-1,3-thiazole
CAS 7210-74-4C11H11NS
Phenyl(1,3-thiazol-2-yl)methanol chemical structure, C10H9NOS, CAS 879-52-7
Phenyl(1,3-thiazol-2-yl)methanol
CAS 879-52-7C10H9NOS
Ethyl 2-benzylthiazole-4-carboxylate chemical structure, C13H13NO2S, CAS 83553-49-5
Ethyl 2-benzylthiazole-4-carboxylate
CAS 83553-49-5C13H13NO2S
Ethyl 2-[(4-chlorophenyl)methyl]-1,3-thiazole-4-carboxylate chemical structure, C13H12ClNO2S, CAS 477872-92-7
Ethyl 2-[(4-chlorophenyl)methyl]-1,3-thiazole-4-carboxylate
CAS 477872-92-7C13H12ClNO2S
2-Benzyl-1,3-thiazole-4-carboxylic acid chemical structure, C11H9NO2S, CAS 36916-44-6
2-Benzyl-1,3-thiazole-4-carboxylic acid
CAS 36916-44-6C11H9NO2S
2-((4-Chlorophenyl)methyl)-1,3-thiazole-4-carboxylic acid chemical structure, C11H8ClNO2S, CAS 477872-93-8
2-((4-Chlorophenyl)methyl)-1,3-thiazole-4-carboxylic acid
CAS 477872-93-8C11H8ClNO2S
2-(4-Methoxybenzyl)thiazole-4-carboxylic acid chemical structure, C12H11NO3S, CAS 477872-94-9
2-(4-Methoxybenzyl)thiazole-4-carboxylic acid
CAS 477872-94-9C12H11NO3S
2-[(2,6-Dichlorophenyl)methyl]-1,3-thiazole-4-carbonyl chloride chemical structure, C11H6Cl3NOS, CAS 263157-86-4
2-[(2,6-Dichlorophenyl)methyl]-1,3-thiazole-4-carbonyl chloride
CAS 263157-86-4C11H6Cl3NOS
2-[3-(Trifluoromethyl)benzyl]-1,3-thiazole-4-carboxylic acid chemical structure, C12H8F3NO2S, CAS 478030-66-9
2-[3-(Trifluoromethyl)benzyl]-1,3-thiazole-4-carboxylic acid
CAS 478030-66-9C12H8F3NO2S
4-tert-Butyl-2-[(4-chlorophenyl)methyl]-1,3-thiazole chemical structure, C14H16ClNS, CAS 696582-89-5
4-tert-Butyl-2-[(4-chlorophenyl)methyl]-1,3-thiazole
CAS 696582-89-5C14H16ClNS
2-Benzyl-4-chloromethylthiazole chemical structure, C11H10ClNS, CAS 36916-36-6
2-Benzyl-4-chloromethylthiazole
CAS 36916-36-6C11H10ClNS
2-[[3-(Trifluoromethyl)phenyl]methyl]-1,3-thiazole-5-carboxylic acid chemical structure, C12H8F3NO2S, CAS 451485-52-2
2-[[3-(Trifluoromethyl)phenyl]methyl]-1,3-thiazole-5-carboxylic acid
CAS 451485-52-2C12H8F3NO2S
2-Benzyl-4-methyl-1,3-thiazole-5-carboxylic acid chemical structure, C12H11NO2S, CAS 876715-98-9
2-Benzyl-4-methyl-1,3-thiazole-5-carboxylic acid
CAS 876715-98-9C12H11NO2S
a-(2-Thiazolyl)-3-((tert-butyldimethylsilyl)oxy)benzyl alcohol chemical structure, C16H23NO2SSi, CAS 155766-82-8
a-(2-Thiazolyl)-3-((tert-butyldimethylsilyl)oxy)benzyl alcohol
CAS 155766-82-8C16H23NO2SSi
Thiazolium, 3,4,5-trimethyl-2-[phenyl[(trimethylsilyl)oxy]methyl]-, iodide chemical structure, C16H24INOSSi, CAS 801219-99-8
Thiazolium, 3,4,5-trimethyl-2-[phenyl[(trimethylsilyl)oxy]methyl]-, iodide
CAS 801219-99-8C16H24INOSSi
Methyl 4-(hydroxy(thiazol-2-yl)methyl)benzoate chemical structure, C12H11NO3S, CAS 482604-57-9
Methyl 4-(hydroxy(thiazol-2-yl)methyl)benzoate
CAS 482604-57-9C12H11NO3S
Thiazole, 2-(chlorophenylmethyl)-4-methyl- chemical structure, C11H10ClNS, CAS 543699-14-5
Thiazole, 2-(chlorophenylmethyl)-4-methyl-
CAS 543699-14-5C11H10ClNS
2-(4-Bromobenzyl)-4-methylthiazole chemical structure, C11H10BrNS, CAS 848605-53-8
2-(4-Bromobenzyl)-4-methylthiazole
CAS 848605-53-8C11H10BrNS
Ethyl 2-(2-(4-bromobenzyl)thiazol-4-yl)acetate chemical structure, C14H14BrNO2S, CAS 344255-80-7
Ethyl 2-(2-(4-bromobenzyl)thiazol-4-yl)acetate
CAS 344255-80-7C14H14BrNO2S
2-[Phenyl(trimethylsilyloxy)methyl]thiazole chemical structure, C13H17NOSSi, CAS 87636-27-9
2-[Phenyl(trimethylsilyloxy)methyl]thiazole
CAS 87636-27-9C13H17NOSSi
(2-Benzylthiazol-4-yl)methanol chemical structure, C11H11NOS, CAS 53542-87-3
(2-Benzylthiazol-4-yl)methanol
CAS 53542-87-3C11H11NOS
(4-Bromophenyl)(thiazol-2-yl)methanol chemical structure, C10H8BrNOS, CAS 356552-30-2
(4-Bromophenyl)(thiazol-2-yl)methanol
CAS 356552-30-2C10H8BrNOS
3-[1-Methoxy-1-(1,3-thiazol-2-yl)propyl]phenol chemical structure, C13H15NO2S, CAS 129424-07-3
3-[1-Methoxy-1-(1,3-thiazol-2-yl)propyl]phenol
CAS 129424-07-3C13H15NO2S
4-(Chloromethyl)-2-((4-chlorophenyl)methyl)-1,3-thiazole chemical structure, C11H9Cl2NS, CAS 73765-41-0
4-(Chloromethyl)-2-((4-chlorophenyl)methyl)-1,3-thiazole
CAS 73765-41-0C11H9Cl2NS