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Murcko scaffold

Ring system with 3 rings and 20 atoms

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
14
With full pages
1
Scaffold SMILES

O=C1NC(=O)C(c2ccccc2)=C1Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NC(=O)C(c2ccccc2)=C1Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

SB 415286 chemical structure, C16H10ClN3O5, CAS 264218-23-7
SB 415286
CAS 264218-23-7C16H10ClN3O5
1H-Pyrrole-2,5-dione, 3-(4-methoxyphenyl)-4-(phenylamino)- chemical structure, C17H14N2O3, CAS 264206-99-7
1H-Pyrrole-2,5-dione, 3-(4-methoxyphenyl)-4-(phenylamino)-
CAS 264206-99-7C17H14N2O3
3-(2-Chlorophenyl)-4-[(3-chlorophenyl)amino]-2,5-dihydro-1H-pyrrole-2,5-dione chemical structure, C16H10Cl2N2O2, CAS 264210-58-4
3-(2-Chlorophenyl)-4-[(3-chlorophenyl)amino]-2,5-dihydro-1H-pyrrole-2,5-dione
CAS 264210-58-4C16H10Cl2N2O2
Slk/stk10-IN-1 chemical structure, C17H13ClN2O3, CAS 264210-49-3
Slk/stk10-IN-1
CAS 264210-49-3C17H13ClN2O3
1-(2-Methoxyethyl)-3-[(4-methoxyphenyl)amino]-4-phenyl-1H-pyrrole-2,5-dione chemical structure, C20H20N2O4, CAS 828931-78-8
1-(2-Methoxyethyl)-3-[(4-methoxyphenyl)amino]-4-phenyl-1H-pyrrole-2,5-dione
CAS 828931-78-8C20H20N2O4
1-Ethyl-3-[(4-methoxyphenyl)amino]-4-phenyl-1H-pyrrole-2,5-dione chemical structure, C19H18N2O3, CAS 264206-79-3
1-Ethyl-3-[(4-methoxyphenyl)amino]-4-phenyl-1H-pyrrole-2,5-dione
CAS 264206-79-3C19H18N2O3
3-[(4-Methoxyphenyl)amino]-1-methyl-4-phenyl-1H-pyrrole-2,5-dione chemical structure, C18H16N2O3, CAS 264206-76-0
3-[(4-Methoxyphenyl)amino]-1-methyl-4-phenyl-1H-pyrrole-2,5-dione
CAS 264206-76-0C18H16N2O3
3-[(4-Methoxyphenyl)amino]-4-phenyl-1H-pyrrole-2,5-dione chemical structure, C17H14N2O3, CAS 264206-68-0
3-[(4-Methoxyphenyl)amino]-4-phenyl-1H-pyrrole-2,5-dione
CAS 264206-68-0C17H14N2O3
1-Butyl-3-(4-methoxyanilino)-4-phenyl-1H-pyrrole-2,5-dione chemical structure, C21H22N2O3, CAS 828938-47-2
1-Butyl-3-(4-methoxyanilino)-4-phenyl-1H-pyrrole-2,5-dione
CAS 828938-47-2C21H22N2O3
3-[4-(Difluoromethoxy)anilino]-4-phenyl-1H-pyrrole-2,5-dione chemical structure, C17H12F2N2O3, CAS 828932-21-4
3-[4-(Difluoromethoxy)anilino]-4-phenyl-1H-pyrrole-2,5-dione
CAS 828932-21-4C17H12F2N2O3
1H-Pyrrole-2,5-dione, 1-[2-(1-methylethoxy)ethyl]-3-(methylphenylamino)-4-phenyl- chemical structure, C22H24N2O3, CAS 1789701-07-0
1H-Pyrrole-2,5-dione, 1-[2-(1-methylethoxy)ethyl]-3-(methylphenylamino)-4-phenyl-
CAS 1789701-07-0C22H24N2O3
1H-Pyrrole-2,5-dione, 3-(methylphenylamino)-1-(2-methylpropyl)-4-phenyl- chemical structure, C21H22N2O2, CAS 1789710-21-9
1H-Pyrrole-2,5-dione, 3-(methylphenylamino)-1-(2-methylpropyl)-4-phenyl-
CAS 1789710-21-9C21H22N2O2
3-(4-Fluoroanilino)-1-methyl-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione chemical structure, C17H12FN3O4, CAS 1786310-00-6
3-(4-Fluoroanilino)-1-methyl-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione
CAS 1786310-00-6C17H12FN3O4
3-(2-Methylsulfanyl-phenylamino)-4-(4-trifluoromethyl-phenyl)-pyrrole-2,5-dione chemical structure, C18H13F3N2O2S, CAS 264207-32-1
3-(2-Methylsulfanyl-phenylamino)-4-(4-trifluoromethyl-phenyl)-pyrrole-2,5-dione
CAS 264207-32-1C18H13F3N2O2S