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Murcko scaffold

Ring system with 3 rings and 20 atoms

41 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
41
With full pages
2
Scaffold SMILES

O=S(=O)(c1ccccc1)n1cccc1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)n1cccc1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 41 of 41 chemicals

1H-Pyrrole, 2-acetyl-1-[(4-methylphenyl)sulfonyl]-5-(3-nitrophenyl)- chemical structure, C19H16N2O5S, CAS 827024-09-9
1H-Pyrrole, 2-acetyl-1-[(4-methylphenyl)sulfonyl]-5-(3-nitrophenyl)-
CAS 827024-09-9C19H16N2O5S
1H-Pyrrole, 2-(4-methoxyphenyl)-1-[(4-methylphenyl)sulfonyl]- chemical structure, C18H17NO3S, CAS 637354-46-2
1H-Pyrrole, 2-(4-methoxyphenyl)-1-[(4-methylphenyl)sulfonyl]-
CAS 637354-46-2C18H17NO3S
1H-Pyrrole, 1-[(4-methylphenyl)sulfonyl]-2-(3-nitrophenyl)- chemical structure, C17H14N2O4S, CAS 637354-45-1
1H-Pyrrole, 1-[(4-methylphenyl)sulfonyl]-2-(3-nitrophenyl)-
CAS 637354-45-1C17H14N2O4S
1-(1-((4-Methoxyphenyl)sulfonyl)-5-phenyl-1H-pyrrol-3-yl)-N-methylmethanamine chemical structure, C19H20N2O3S, CAS 881732-42-9
1-(1-((4-Methoxyphenyl)sulfonyl)-5-phenyl-1H-pyrrol-3-yl)-N-methylmethanamine
CAS 881732-42-9C19H20N2O3S
1-{[3-(Methylsulfonyl)phenyl]sulfonyl}-5-phenyl-1H-pyrrole-3-carbaldehyde chemical structure, C18H15NO5S2, CAS 881676-54-6
1-{[3-(Methylsulfonyl)phenyl]sulfonyl}-5-phenyl-1H-pyrrole-3-carbaldehyde
CAS 881676-54-6C18H15NO5S2
(1-((4-Fluorophenyl)sulfonyl)-5-phenyl-1H-pyrrol-3-yl)methanol chemical structure, C17H14FNO3S, CAS 881673-32-1
(1-((4-Fluorophenyl)sulfonyl)-5-phenyl-1H-pyrrol-3-yl)methanol
CAS 881673-32-1C17H14FNO3S
Ethyl 1-[(4-methoxyphenyl)sulfonyl]-5-phenyl-1H-pyrrole-3-carboxylate chemical structure, C20H19NO5S, CAS 881673-36-5
Ethyl 1-[(4-methoxyphenyl)sulfonyl]-5-phenyl-1H-pyrrole-3-carboxylate
CAS 881673-36-5C20H19NO5S
Ethyl 2-methyl-5-phenyl-1-(phenylsulfonyl)-1H-pyrrole-3-carboxylate chemical structure, C20H19NO4S, CAS 881673-69-4
Ethyl 2-methyl-5-phenyl-1-(phenylsulfonyl)-1H-pyrrole-3-carboxylate
CAS 881673-69-4C20H19NO4S
{1-[(4-Methylphenyl)sulfonyl]-5-phenyl-1H-pyrrol-3-yl}methanol chemical structure, C18H17NO3S, CAS 881673-30-9
{1-[(4-Methylphenyl)sulfonyl]-5-phenyl-1H-pyrrol-3-yl}methanol
CAS 881673-30-9C18H17NO3S
Ethyl 2-chloro-5-phenyl-1-(phenylsulfonyl)-1H-pyrrole-3-carboxylate chemical structure, C19H16ClNO4S, CAS 881675-37-2
Ethyl 2-chloro-5-phenyl-1-(phenylsulfonyl)-1H-pyrrole-3-carboxylate
CAS 881675-37-2C19H16ClNO4S
Ethyl 1-[(4-methylphenyl)sulfonyl]-5-phenyl-1H-pyrrole-3-carboxylate chemical structure, C20H19NO4S, CAS 881673-29-6
Ethyl 1-[(4-methylphenyl)sulfonyl]-5-phenyl-1H-pyrrole-3-carboxylate
CAS 881673-29-6C20H19NO4S
N-Methyl-1-(5-phenyl-1-(phenylsulfonyl)-1H-pyrrol-3-yl)methanamine chemical structure, C18H18N2O2S, CAS 881678-78-0
N-Methyl-1-(5-phenyl-1-(phenylsulfonyl)-1H-pyrrol-3-yl)methanamine
CAS 881678-78-0C18H18N2O2S
Ethyl 1-((4-fluorophenyl)sulfonyl)-2-methyl-5-phenyl-1H-pyrrole-3-carboxylate chemical structure, C20H18FNO4S, CAS 881673-38-7
Ethyl 1-((4-fluorophenyl)sulfonyl)-2-methyl-5-phenyl-1H-pyrrole-3-carboxylate
CAS 881673-38-7C20H18FNO4S
[2-Chloro-5-phenyl-1-(phenylsulfonyl)-1H-pyrrol-3-yl]methanol chemical structure, C17H14ClNO3S, CAS 881675-88-3
[2-Chloro-5-phenyl-1-(phenylsulfonyl)-1H-pyrrol-3-yl]methanol
CAS 881675-88-3C17H14ClNO3S
Ethyl 5-(4-fluorophenyl)-1-[(4-fluorophenyl)sulfonyl]-1H-pyrrole-3-carboxylate chemical structure, C19H15F2NO4S, CAS 881673-56-9
Ethyl 5-(4-fluorophenyl)-1-[(4-fluorophenyl)sulfonyl]-1H-pyrrole-3-carboxylate
CAS 881673-56-9C19H15F2NO4S
Ethyl 5-(4-fluorophenyl)-1-(phenylsulfonyl)-1H-pyrrole-3-carboxylate chemical structure, C19H16FNO4S, CAS 881673-55-8
Ethyl 5-(4-fluorophenyl)-1-(phenylsulfonyl)-1H-pyrrole-3-carboxylate
CAS 881673-55-8C19H16FNO4S
Methyl 4-methyl-5-phenyl-1-(phenylsulfonyl)-1H-pyrrole-3-carboxylate chemical structure, C19H17NO4S, CAS 881675-49-6
Methyl 4-methyl-5-phenyl-1-(phenylsulfonyl)-1H-pyrrole-3-carboxylate
CAS 881675-49-6C19H17NO4S
1-(4-Methylbenzene-1-sulfonyl)-5-phenyl-1H-pyrrole-3-carboxamide chemical structure, C18H16N2O3S, CAS 1381767-12-9
1-(4-Methylbenzene-1-sulfonyl)-5-phenyl-1H-pyrrole-3-carboxamide
CAS 1381767-12-9C18H16N2O3S
1-[5-(4-Methoxyphenyl)-1-(4-methylbenzene-1-sulfonyl)-1H-pyrrol-2-yl]ethan-1-one chemical structure, C20H19NO4S, CAS 827024-10-2
1-[5-(4-Methoxyphenyl)-1-(4-methylbenzene-1-sulfonyl)-1H-pyrrol-2-yl]ethan-1-one
CAS 827024-10-2C20H19NO4S
1-[1-(4-Methylbenzene-1-sulfonyl)-5-phenyl-1H-pyrrol-2-yl]ethan-1-one chemical structure, C19H17NO3S, CAS 827024-08-8
1-[1-(4-Methylbenzene-1-sulfonyl)-5-phenyl-1H-pyrrol-2-yl]ethan-1-one
CAS 827024-08-8C19H17NO3S
2-(3-((2-(2-Fluorophenyl)-4-((methylamino)methyl)-1H-pyrrol-1-yl)sulfonyl)phenoxy)-N-methylacetamide chemical structure, C21H22FN3O4S, CAS 1610043-51-0
2-(3-((2-(2-Fluorophenyl)-4-((methylamino)methyl)-1H-pyrrol-1-yl)sulfonyl)phenoxy)-N-methylacetamide
CAS 1610043-51-0C21H22FN3O4S
2-Methyl-5-phenyl-1-(phenylsulfonyl)-1H-pyrrole-3-carbaldehyde chemical structure, C18H15NO3S, CAS 881678-67-7
2-Methyl-5-phenyl-1-(phenylsulfonyl)-1H-pyrrole-3-carbaldehyde
CAS 881678-67-7C18H15NO3S
2-Chloro-5-phenyl-1-(phenylsulfonyl)-1H-pyrrole-3-carbaldehyde chemical structure, C17H12ClNO3S, CAS 881676-18-2
2-Chloro-5-phenyl-1-(phenylsulfonyl)-1H-pyrrole-3-carbaldehyde
CAS 881676-18-2C17H12ClNO3S
1-[(4-Methylphenyl)sulfonyl]-5-phenyl-1H-pyrrole-3-carbaldehyde chemical structure, C18H15NO3S, CAS 881673-31-0
1-[(4-Methylphenyl)sulfonyl]-5-phenyl-1H-pyrrole-3-carbaldehyde
CAS 881673-31-0C18H15NO3S