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Murcko scaffold

Ring system with 3 rings and 20 atoms

45 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
45
With full pages
3
Scaffold SMILES

O=S(=O)(c1cccnc1)n1cccc1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1cccnc1)n1cccc1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 45 of 45 chemicals

Vonoprazan chemical structure, C17H16FN3O2S, CAS 881681-00-1
Vonoprazan
CAS 881681-00-1C17H16FN3O2S
Vonoprazan fumarate chemical structure, C21H20FN3O6S, CAS 1260141-27-2
Vonoprazan fumarate
CAS 1260141-27-2C21H20FN3O6S
N-Methyl-1-(5-phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methanamine chemical structure, C17H17N3O2S, CAS 881732-90-7
N-Methyl-1-(5-phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methanamine
CAS 881732-90-7C17H17N3O2S
N-Methyl-1-{1-(pyridin-3-ylsulfonyl)-5-[2-(trifluoromethyl)phenyl]-1H-pyrrol-3-yl}methanamine dihydrochloride chemical structure, C18H18Cl2F3N3O2S, CAS 881681-03-4
N-Methyl-1-{1-(pyridin-3-ylsulfonyl)-5-[2-(trifluoromethyl)phenyl]-1H-pyrrol-3-yl}methanamine dihydrochloride
CAS 881681-03-4C18H18Cl2F3N3O2S
1-(5-(4-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine chemical structure, C17H16FN3O2S, CAS 881733-36-4
1-(5-(4-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine
CAS 881733-36-4C17H16FN3O2S
Vonoprazan impurity 100 chemical structure, C17H16FN3O2S, CAS 881733-45-5
Vonoprazan impurity 100
CAS 881733-45-5C17H16FN3O2S
Ethyl 2-methyl-5-phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carboxylate chemical structure, C19H18N2O4S, CAS 881675-59-8
Ethyl 2-methyl-5-phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carboxylate
CAS 881675-59-8C19H18N2O4S
N-Methyl-1-(5-phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methanamine fumarate chemical structure, C21H21N3O6S, CAS 928325-82-0
N-Methyl-1-(5-phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methanamine fumarate
CAS 928325-82-0C21H21N3O6S
1-(5-(2,6-Difluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine chemical structure, C17H15F2N3O2S, CAS 928325-41-1
1-(5-(2,6-Difluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine
CAS 928325-41-1C17H15F2N3O2S
1-(2-Chloro-5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine fumarate chemical structure, C21H19ClFN3O6S, CAS 928325-69-3
1-(2-Chloro-5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine fumarate
CAS 928325-69-3C21H19ClFN3O6S
2-Chloro vonoprazan chemical structure, C17H15ClFN3O2S, CAS 928325-68-2
2-Chloro vonoprazan
CAS 928325-68-2C17H15ClFN3O2S
2-Desfluoro vonoprazan hydrocloride chemical structure, C17H18ClN3O2S, CAS 2650810-07-2
2-Desfluoro vonoprazan hydrocloride
CAS 2650810-07-2C17H18ClN3O2S
2'-Desfluoro 4-fluoro vonoprazan hydrochloride chemical structure, C17H17ClFN3O2S, CAS 2650821-03-5
2'-Desfluoro 4-fluoro vonoprazan hydrochloride
CAS 2650821-03-5C17H17ClFN3O2S
4-Methyl-5-phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde chemical structure, C17H14N2O3S, CAS 881677-34-5
4-Methyl-5-phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde
CAS 881677-34-5C17H14N2O3S
2-Methyl-5-phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde chemical structure, C17H14N2O3S, CAS 881676-44-4
2-Methyl-5-phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde
CAS 881676-44-4C17H14N2O3S
5-Phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde chemical structure, C16H12N2O3S, CAS 881676-90-0
5-Phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde
CAS 881676-90-0C16H12N2O3S
5-(2-Fluorophenyl)-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-carboxaldehyde chemical structure, C16H11FN2O3S, CAS 881677-11-8
5-(2-Fluorophenyl)-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-carboxaldehyde
CAS 881677-11-8C16H11FN2O3S
1-[(6-Methoxypyridin-3-yl)sulfonyl]-5-phenyl-1H-pyrrole-3-carbaldehyde chemical structure, C17H14N2O4S, CAS 881676-92-2
1-[(6-Methoxypyridin-3-yl)sulfonyl]-5-phenyl-1H-pyrrole-3-carbaldehyde
CAS 881676-92-2C17H14N2O4S
1-(6-Chloropyridin-3-ylsulfonyl)-5-phenyl-1H-pyrrole-3-carbaldehyde chemical structure, C16H11ClN2O3S, CAS 881676-94-4
1-(6-Chloropyridin-3-ylsulfonyl)-5-phenyl-1H-pyrrole-3-carbaldehyde
CAS 881676-94-4C16H11ClN2O3S
1-(2-Chloropyridin-3-ylsulfonyl)-5-phenyl-1H-pyrrole-3-carbaldehyde chemical structure, C16H11ClN2O3S, CAS 881676-96-6
1-(2-Chloropyridin-3-ylsulfonyl)-5-phenyl-1H-pyrrole-3-carbaldehyde
CAS 881676-96-6C16H11ClN2O3S
1-[(6-Chloro-5-methylpyridin-3-yl)sulfonyl]-5-phenyl-1H-pyrrole-3-carbaldehyde chemical structure, C17H13ClN2O3S, CAS 881677-00-5
1-[(6-Chloro-5-methylpyridin-3-yl)sulfonyl]-5-phenyl-1H-pyrrole-3-carbaldehyde
CAS 881677-00-5C17H13ClN2O3S
2-Chloro-5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde chemical structure, C16H10ClFN2O3S, CAS 928324-80-5
2-Chloro-5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde
CAS 928324-80-5C16H10ClFN2O3S
1-[(2-Methyl-3-pyridinyl)sulfonyl]-5-phenylpyrrole-3-carbaldehyde chemical structure, C17H14N2O3S, CAS 928324-67-8
1-[(2-Methyl-3-pyridinyl)sulfonyl]-5-phenylpyrrole-3-carbaldehyde
CAS 928324-67-8C17H14N2O3S
Vonoprazan impurity 279 chemical structure, C16H13FN2O2S, CAS 1870905-87-5
Vonoprazan impurity 279
CAS 1870905-87-5C16H13FN2O2S