CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 23 atoms

19 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
19
With full pages
5
Scaffold SMILES

O=C(CCCc1nc(-c2ccccc2)no1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CCCc1nc(-c2ccccc2)no1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

4-[4-[3-(2-Chlorophenyl)-1,2,4-oxadiazol-5-yl]butanoylamino]benzamide chemical structure, C19H17ClN4O3, CAS 836662-90-9
4-[4-[3-(2-Chlorophenyl)-1,2,4-oxadiazol-5-yl]butanoylamino]benzamide
CAS 836662-90-9C19H17ClN4O3
4-[3-(3,4-Dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]-N-(2-methoxyphenyl)butanamide chemical structure, C21H23N3O5, CAS 835899-85-9
4-[3-(3,4-Dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]-N-(2-methoxyphenyl)butanamide
CAS 835899-85-9C21H23N3O5
4-[3-(3,4-Dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]-N-[2-(trifluoromethyl)phenyl]butanamide chemical structure, C21H20F3N3O4, CAS 896829-88-2
4-[3-(3,4-Dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]-N-[2-(trifluoromethyl)phenyl]butanamide
CAS 896829-88-2C21H20F3N3O4
4-[3-(3,4-Dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]-N-(4-methoxyphenyl)butanamide chemical structure, C21H23N3O5, CAS 878981-18-1
4-[3-(3,4-Dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]-N-(4-methoxyphenyl)butanamide
CAS 878981-18-1C21H23N3O5
4-[4-[3-(3-Methoxyphenyl)-1,2,4-oxadiazol-5-yl]butanoylamino]benzamide chemical structure, C20H20N4O4, CAS 835888-16-9
4-[4-[3-(3-Methoxyphenyl)-1,2,4-oxadiazol-5-yl]butanoylamino]benzamide
CAS 835888-16-9C20H20N4O4
N-(3-Methoxyphenyl)-4-[3-(3,4,5-trimethoxyphenyl)-1,2,4-oxadiazol-5-yl]butanamide chemical structure, C22H25N3O6, CAS 833435-77-1
N-(3-Methoxyphenyl)-4-[3-(3,4,5-trimethoxyphenyl)-1,2,4-oxadiazol-5-yl]butanamide
CAS 833435-77-1C22H25N3O6
4-(4-(3-(3,4-Dimethoxyphenyl)-1,2,4-oxadiazol-5-yl)butanamido)benzamide chemical structure, C21H22N4O5, CAS 899404-38-7
4-(4-(3-(3,4-Dimethoxyphenyl)-1,2,4-oxadiazol-5-yl)butanamido)benzamide
CAS 899404-38-7C21H22N4O5
4-[4-[3-(4-Methoxyphenyl)-1,2,4-oxadiazol-5-yl]butanoylamino]benzamide chemical structure, C20H20N4O4, CAS 900288-70-2
4-[4-[3-(4-Methoxyphenyl)-1,2,4-oxadiazol-5-yl]butanoylamino]benzamide
CAS 900288-70-2C20H20N4O4
N-(3,4-Dimethylphenyl)-4-[3-(3,4,5-trimethoxyphenyl)-1,2,4-oxadiazol-5-yl]butanamide chemical structure, C23H27N3O5, CAS 838850-13-8
N-(3,4-Dimethylphenyl)-4-[3-(3,4,5-trimethoxyphenyl)-1,2,4-oxadiazol-5-yl]butanamide
CAS 838850-13-8C23H27N3O5
4-[3-(3,4-Dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]-N-(4-nitrophenyl)butanamide chemical structure, C20H20N4O6, CAS 833441-28-4
4-[3-(3,4-Dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]-N-(4-nitrophenyl)butanamide
CAS 833441-28-4C20H20N4O6
N-(4-Bromophenyl)-4-(3-phenyl-1,2,4-oxadiazol-5-yl)butanamide chemical structure, C18H16BrN3O2, CAS 900136-55-2
N-(4-Bromophenyl)-4-(3-phenyl-1,2,4-oxadiazol-5-yl)butanamide
CAS 900136-55-2C18H16BrN3O2
N-(4-Isopropylphenyl)-4-(3-phenyl-1,2,4-oxadiazol-5-yl)butanamide chemical structure, C21H23N3O2, CAS 900136-59-6
N-(4-Isopropylphenyl)-4-(3-phenyl-1,2,4-oxadiazol-5-yl)butanamide
CAS 900136-59-6C21H23N3O2
N-(3-Chloro-4-fluorophenyl)-4-(3-phenyl-1,2,4-oxadiazol-5-yl)butanamide chemical structure, C18H15ClFN3O2, CAS 900135-98-0
N-(3-Chloro-4-fluorophenyl)-4-(3-phenyl-1,2,4-oxadiazol-5-yl)butanamide
CAS 900135-98-0C18H15ClFN3O2
4-[3-(2-Chlorophenyl)-1,2,4-oxadiazol-5-yl]-N-(2,4-dimethoxyphenyl)butanamide chemical structure, C20H20ClN3O4, CAS 900136-21-2
4-[3-(2-Chlorophenyl)-1,2,4-oxadiazol-5-yl]-N-(2,4-dimethoxyphenyl)butanamide
CAS 900136-21-2C20H20ClN3O4
4-[3-(2-Chlorophenyl)-1,2,4-oxadiazol-5-yl]-N-[4-(methylsulfamoyl)phenyl]butanamide chemical structure, C19H19ClN4O4S, CAS 945201-49-0
4-[3-(2-Chlorophenyl)-1,2,4-oxadiazol-5-yl]-N-[4-(methylsulfamoyl)phenyl]butanamide
CAS 945201-49-0C19H19ClN4O4S
2-({4-[3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl]butanoyl}amino)benzoic acid chemical structure, C19H16ClN3O4, CAS 845889-90-9
2-({4-[3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl]butanoyl}amino)benzoic acid
CAS 845889-90-9C19H16ClN3O4
4-[3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl]-N-[4-(methylsulfamoyl)phenyl]butanamide chemical structure, C19H19ClN4O4S, CAS 931325-29-0
4-[3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl]-N-[4-(methylsulfamoyl)phenyl]butanamide
CAS 931325-29-0C19H19ClN4O4S
Methyl 4-({4-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]butanoyl}amino)benzoate chemical structure, C21H21N3O5, CAS 945201-73-0
Methyl 4-({4-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]butanoyl}amino)benzoate
CAS 945201-73-0C21H21N3O5
1,2,4-Oxadiazole-5-butanamide, N-[4-chloro-3-[(diethylamino)sulfonyl]phenyl]-3-(4-fluorophenyl)- chemical structure, C22H24ClFN4O4S, CAS 1322062-58-7
1,2,4-Oxadiazole-5-butanamide, N-[4-chloro-3-[(diethylamino)sulfonyl]phenyl]-3-(4-fluorophenyl)-
CAS 1322062-58-7C22H24ClFN4O4S