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Murcko scaffold

Ring system with 3 rings and 23 atoms

17 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
17
With full pages
4
Scaffold SMILES

O=C(C=Cc1ccc(-c2ccccc2)o1)NCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccc(-c2ccccc2)o1)NCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

(2E)-N-Benzyl-2-cyano-3-[5-(2,3-dichlorophenyl)furan-2-yl]prop-2-enamide chemical structure, C21H14Cl2N2O2, CAS 306312-90-3
(2E)-N-Benzyl-2-cyano-3-[5-(2,3-dichlorophenyl)furan-2-yl]prop-2-enamide
CAS 306312-90-3C21H14Cl2N2O2
N-Benzyl-2-cyano-3-[5-(3,4-dichlorophenyl)furan-2-yl]-N-methylprop-2-enamide chemical structure, C22H16Cl2N2O2, CAS 518350-21-5
N-Benzyl-2-cyano-3-[5-(3,4-dichlorophenyl)furan-2-yl]-N-methylprop-2-enamide
CAS 518350-21-5C22H16Cl2N2O2
Ethyl 4-[5-[(E)-3-(benzylamino)-2-cyano-3-oxoprop-1-enyl]furan-2-yl]benzoate chemical structure, C24H20N2O4, CAS 306312-57-2
Ethyl 4-[5-[(E)-3-(benzylamino)-2-cyano-3-oxoprop-1-enyl]furan-2-yl]benzoate
CAS 306312-57-2C24H20N2O4
3-{5-[(1E)-3-(Benzylamino)-2-cyano-3-oxoprop-1-en-1-yl]furan-2-yl}benzoic acid chemical structure, C22H16N2O4, CAS 306312-89-0
3-{5-[(1E)-3-(Benzylamino)-2-cyano-3-oxoprop-1-en-1-yl]furan-2-yl}benzoic acid
CAS 306312-89-0C22H16N2O4
(E)-N-Benzyl-3-(5-(3-chlorophenyl)furan-2-yl)-2-cyanoacrylamide chemical structure, C21H15ClN2O2, CAS 306312-91-4
(E)-N-Benzyl-3-(5-(3-chlorophenyl)furan-2-yl)-2-cyanoacrylamide
CAS 306312-91-4C21H15ClN2O2
(E)-N-Benzyl-2-cyano-3-(5-(p-tolyl)furan-2-yl)acrylamide chemical structure, C22H18N2O2, CAS 324540-66-1
(E)-N-Benzyl-2-cyano-3-(5-(p-tolyl)furan-2-yl)acrylamide
CAS 324540-66-1C22H18N2O2
(E)-N-Benzyl-3-[5-(4-bromophenyl)furan-2-yl]-2-cyanoprop-2-enamide chemical structure, C21H15BrN2O2, CAS 306312-82-3
(E)-N-Benzyl-3-[5-(4-bromophenyl)furan-2-yl]-2-cyanoprop-2-enamide
CAS 306312-82-3C21H15BrN2O2
(E)-3-(5-(3-Chlorophenyl)furan-2-yl)-2-cyano-N-(2-methoxy-4-methylbenzyl)acrylamide chemical structure, C23H19ClN2O3, CAS 850902-92-0
(E)-3-(5-(3-Chlorophenyl)furan-2-yl)-2-cyano-N-(2-methoxy-4-methylbenzyl)acrylamide
CAS 850902-92-0C23H19ClN2O3
(2E)-N-Benzyl-2-cyano-3-[5-(3,4-dichlorophenyl)furan-2-yl]prop-2-enamide chemical structure, C21H14Cl2N2O2, CAS 306312-83-4
(2E)-N-Benzyl-2-cyano-3-[5-(3,4-dichlorophenyl)furan-2-yl]prop-2-enamide
CAS 306312-83-4C21H14Cl2N2O2
(E)-N-Benzyl-3-[5-(4-chloro-2-nitrophenyl)furan-2-yl]-2-cyanoprop-2-enamide chemical structure, C21H14ClN3O4, CAS 306312-55-0
(E)-N-Benzyl-3-[5-(4-chloro-2-nitrophenyl)furan-2-yl]-2-cyanoprop-2-enamide
CAS 306312-55-0C21H14ClN3O4
(E)-N-Benzyl-2-cyano-3-[5-(2-fluorophenyl)furan-2-yl]prop-2-enamide chemical structure, C21H15FN2O2, CAS 874602-33-2
(E)-N-Benzyl-2-cyano-3-[5-(2-fluorophenyl)furan-2-yl]prop-2-enamide
CAS 874602-33-2C21H15FN2O2
N-Benzyl-3-[5-(2-bromophenyl)furan-2-yl]-2-cyanoprop-2-enamide chemical structure, C21H15BrN2O2, CAS 940799-94-0
N-Benzyl-3-[5-(2-bromophenyl)furan-2-yl]-2-cyanoprop-2-enamide
CAS 940799-94-0C21H15BrN2O2
N-Benzyl-3-(5-(3-nitrophenyl)-2-furyl)-2-propenamide chemical structure, C20H16N2O4, CAS 853351-47-0
N-Benzyl-3-(5-(3-nitrophenyl)-2-furyl)-2-propenamide
CAS 853351-47-0C20H16N2O4
N-(4-Methoxybenzyl)-3-(5-(3-nitrophenyl)-2-furyl)-2-propenamide chemical structure, C21H18N2O5, CAS 853351-53-8
N-(4-Methoxybenzyl)-3-(5-(3-nitrophenyl)-2-furyl)-2-propenamide
CAS 853351-53-8C21H18N2O5
3-(5-(2-Chlorophenyl)-2-furyl)-N-(4-methoxybenzyl)-2-propenamide chemical structure, C21H18ClNO3, CAS 853356-04-4
3-(5-(2-Chlorophenyl)-2-furyl)-N-(4-methoxybenzyl)-2-propenamide
CAS 853356-04-4C21H18ClNO3
N-Benzyl-3-(5-(2-chlorophenyl)-2-furyl)-2-propenamide chemical structure, C20H16ClNO2, CAS 853356-05-5
N-Benzyl-3-(5-(2-chlorophenyl)-2-furyl)-2-propenamide
CAS 853356-05-5C20H16ClNO2
(Z)-N-Benzyl-3-[5-(4-chlorophenyl)furan-2-yl]-2-cyanoprop-2-enamide chemical structure, C21H15ClN2O2, CAS 306312-51-6
(Z)-N-Benzyl-3-[5-(4-chlorophenyl)furan-2-yl]-2-cyanoprop-2-enamide
CAS 306312-51-6C21H15ClN2O2