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Murcko scaffold

N-Benzyl-2-((5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)thio)acetamide scaffold

5 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
5
With full pages
3
Scaffold SMILES

O=C(CSc1nnc(-c2ccncc2)o1)NCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Benzyl-2-((5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)thio)acetamide page
Murcko scaffold O=C(CSc1nnc(-c2ccncc2)o1)NCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

N-Benzyl-2-((5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)thio)acetamide chemical structure, C16H14N4O2S, CAS 496029-02-8
N-Benzyl-2-((5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)thio)acetamide
CAS 496029-02-8C16H14N4O2S
Ethyl 4-{[({[5-(4-pyridinyl)-1,3,4-oxadiazol-2-yl]thio}acetyl)amino]methyl}benzoate chemical structure, C19H18N4O4S, CAS 501112-69-2
Ethyl 4-{[({[5-(4-pyridinyl)-1,3,4-oxadiazol-2-yl]thio}acetyl)amino]methyl}benzoate
CAS 501112-69-2C19H18N4O4S
N-(2-Chlorobenzyl)-2-((5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)thio)acetamide chemical structure, C16H13ClN4O2S, CAS 721406-24-2
N-(2-Chlorobenzyl)-2-((5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)thio)acetamide
CAS 721406-24-2C16H13ClN4O2S
N-[(4-Methylphenyl)methyl]-2-[(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)sulfanyl]acetamide chemical structure, C17H16N4O2S, CAS 899988-97-7
N-[(4-Methylphenyl)methyl]-2-[(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)sulfanyl]acetamide
CAS 899988-97-7C17H16N4O2S
N-(4-Fluorobenzyl)-2-((5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)thio)acetamide chemical structure, C16H13FN4O2S, CAS 899945-93-8
N-(4-Fluorobenzyl)-2-((5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)thio)acetamide
CAS 899945-93-8C16H13FN4O2S