CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 25 atoms

5 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
5
With full pages
3
Scaffold SMILES

O=C(COC(=O)c1cccnc1)Nc1c[nH]n(-c2ccccc2)c1=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COC(=O)c1cccnc1)Nc1c[nH]n(-c2ccccc2)c1=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

[(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)carbamoyl]methyl 2-chloropyridine-3-carboxylate chemical structure, C19H17ClN4O4, CAS 736953-47-2
[(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)carbamoyl]methyl 2-chloropyridine-3-carboxylate
CAS 736953-47-2C19H17ClN4O4
[(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)carbamoyl]methyl 2-(methylsulfanyl)pyridine-3-carboxylate chemical structure, C20H20N4O4S, CAS 479704-93-3
[(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)carbamoyl]methyl 2-(methylsulfanyl)pyridine-3-carboxylate
CAS 479704-93-3C20H20N4O4S
[(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)carbamoyl]methyl 6-chloropyridine-3-carboxylate chemical structure, C19H17ClN4O4, CAS 852709-50-3
[(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)carbamoyl]methyl 6-chloropyridine-3-carboxylate
CAS 852709-50-3C19H17ClN4O4
1-[(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)carbamoyl]ethyl 6-chloropyridine-3-carboxylate chemical structure, C20H19ClN4O4, CAS 380556-22-9
1-[(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)carbamoyl]ethyl 6-chloropyridine-3-carboxylate
CAS 380556-22-9C20H19ClN4O4
1-[(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)carbamoyl]ethyl 2-chloropyridine-3-carboxylate chemical structure, C20H19ClN4O4, CAS 869867-99-2
1-[(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)carbamoyl]ethyl 2-chloropyridine-3-carboxylate
CAS 869867-99-2C20H19ClN4O4