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Murcko scaffold

Ring system with 4 rings and 23 atoms

5 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
5
With full pages
3
Scaffold SMILES

O=c1c(Cc2ccccc2)cnc2c(-c3ccccc3)c[nH]n12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c(Cc2ccccc2)cnc2c(-c3ccccc3)c[nH]n12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

6-Benzyl-2,5-dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C21H19N3O, CAS 331434-03-8
6-Benzyl-2,5-dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
CAS 331434-03-8C21H19N3O
6-Benzyl-5-methyl-3-phenyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C21H16F3N3O, CAS 701226-88-2
6-Benzyl-5-methyl-3-phenyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
CAS 701226-88-2C21H16F3N3O
6-Benzyl-3-(2-methoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C22H21N3O2, CAS 701230-47-9
6-Benzyl-3-(2-methoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7(4H)-one
CAS 701230-47-9C22H21N3O2
6-Benzyl-2-(methoxymethyl)-5-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C22H21N3O2, CAS 878977-94-7
6-Benzyl-2-(methoxymethyl)-5-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
CAS 878977-94-7C22H21N3O2
6-Benzyl-3-(3,4-dimethoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C23H23N3O3, CAS 838890-78-1
6-Benzyl-3-(3,4-dimethoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7(4H)-one
CAS 838890-78-1C23H23N3O3