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Murcko scaffold

Ring system with 3 rings and 20 atoms

61 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 20
Chemicals: 61
With full pages: 7

Scaffold SMILES

O=C(Nc1ccccc1)c1ccc(Cn2cccn2)o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(Nc1ccccc1)c1ccc(Cn2cccn2)o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 61 chemicals

5-[(3,5-Dimethylpyrazol-1-yl)methyl]-N-(4-ethoxyphenyl)furan-2-carboxamide chemical structure, C19H21N3O3, CAS 514836-93-2

5-[(3,5-Dimethylpyrazol-1-yl)methyl]-N-(4-ethoxyphenyl)furan-2-carboxamide

CAS 514836-93-2C₁₉H₂₁N₃O₃

N-(3-Methoxyphenyl)-5-[(4-nitropyrazol-1-yl)methyl]furan-2-carboxamide chemical structure, C16H14N4O5, CAS 514817-57-3

N-(3-Methoxyphenyl)-5-[(4-nitropyrazol-1-yl)methyl]furan-2-carboxamide

CAS 514817-57-3C₁₆H₁₄N₄O₅

N-(3-Chloro-4-methylphenyl)-5-[(3,5-dimethylpyrazol-1-yl)methyl]furan-2-carboxamide chemical structure, C18H18ClN3O2, CAS 514854-70-7

N-(3-Chloro-4-methylphenyl)-5-[(3,5-dimethylpyrazol-1-yl)methyl]furan-2-carboxamide

CAS 514854-70-7C₁₈H₁₈ClN₃O₂

5-[(3,5-Dimethylpyrazol-1-yl)methyl]-N-(2-fluoro-5-methylphenyl)furan-2-carboxamide chemical structure, C18H18FN3O2, CAS 515151-34-5

5-[(3,5-Dimethylpyrazol-1-yl)methyl]-N-(2-fluoro-5-methylphenyl)furan-2-carboxamide

CAS 515151-34-5C₁₈H₁₈FN₃O₂

5-[(4-Chloro-3,5-dimethyl-1H-pyrazol-1-yl)methyl]-N-(3,5-dimethylphenyl)-2-furamide chemical structure, C19H20ClN3O2, CAS 515831-89-7

5-[(4-Chloro-3,5-dimethyl-1H-pyrazol-1-yl)methyl]-N-(3,5-dimethylphenyl)-2-furamide

CAS 515831-89-7C₁₉H₂₀ClN₃O₂

5-[(4-Chloro-3,5-dimethylpyrazol-1-yl)methyl]-N-(3,5-dimethoxyphenyl)furan-2-carboxamide chemical structure, C19H20ClN3O4, CAS 515847-41-3

5-[(4-Chloro-3,5-dimethylpyrazol-1-yl)methyl]-N-(3,5-dimethoxyphenyl)furan-2-carboxamide

CAS 515847-41-3C₁₉H₂₀ClN₃O₄

5-[(4-Chloro-3,5-dimethylpyrazol-1-yl)methyl]-N-(4-fluoro-3-nitrophenyl)furan-2-carboxamide chemical structure, C17H14ClFN4O4, CAS 515832-67-4

5-[(4-Chloro-3,5-dimethylpyrazol-1-yl)methyl]-N-(4-fluoro-3-nitrophenyl)furan-2-carboxamide

CAS 515832-67-4C₁₇H₁₄ClFN₄O₄

N-(5-Chloro-2-methoxyphenyl)-5-[(3,5-dimethylpyrazol-1-yl)methyl]furan-2-carboxamide chemical structure, C18H18ClN3O3, CAS 515177-52-3

N-(5-Chloro-2-methoxyphenyl)-5-[(3,5-dimethylpyrazol-1-yl)methyl]furan-2-carboxamide

CAS 515177-52-3C₁₈H₁₈ClN₃O₃

5-[(4-Chloro-5-methyl-3-nitropyrazol-1-yl)methyl]-N-(3,4,5-trimethoxyphenyl)furan-2-carboxamide chemical structure, C19H19ClN4O7, CAS 515122-55-1

5-[(4-Chloro-5-methyl-3-nitropyrazol-1-yl)methyl]-N-(3,4,5-trimethoxyphenyl)furan-2-carboxamide

CAS 515122-55-1C₁₉H₁₉ClN₄O₇

5-[(4-Bromo-3,5-dimethylpyrazol-1-yl)methyl]-N-(5-chloro-2-methoxyphenyl)furan-2-carboxamide chemical structure, C18H17BrClN3O3, CAS 514842-34-3

5-[(4-Bromo-3,5-dimethylpyrazol-1-yl)methyl]-N-(5-chloro-2-methoxyphenyl)furan-2-carboxamide

CAS 514842-34-3C₁₈H₁₇BrClN₃O₃

N-(4-Bromo-2-methylphenyl)-5-[(3,5-dimethylpyrazol-1-yl)methyl]furan-2-carboxamide chemical structure, C18H18BrN3O2, CAS 514818-33-8

N-(4-Bromo-2-methylphenyl)-5-[(3,5-dimethylpyrazol-1-yl)methyl]furan-2-carboxamide

CAS 514818-33-8C₁₈H₁₈BrN₃O₂

Methyl 2-[[5-[(4-chloro-5-methyl-3-nitropyrazol-1-yl)methyl]furan-2-carbonyl]amino]benzoate chemical structure, C18H15ClN4O6, CAS 514837-70-8

Methyl 2-[[5-[(4-chloro-5-methyl-3-nitropyrazol-1-yl)methyl]furan-2-carbonyl]amino]benzoate

CAS 514837-70-8C₁₈H₁₅ClN₄O₆

N-(4-Iodophenyl)-5-[(4-nitropyrazol-1-yl)methyl]furan-2-carboxamide chemical structure, C15H11IN4O4, CAS 514839-27-1

N-(4-Iodophenyl)-5-[(4-nitropyrazol-1-yl)methyl]furan-2-carboxamide

CAS 514839-27-1C₁₅H₁₁IN₄O₄

5-[(3,5-Dimethylpyrazol-1-yl)methyl]-N-[4-(ethylsulfamoyl)phenyl]furan-2-carboxamide chemical structure, C19H22N4O4S, CAS 514841-03-3

5-[(3,5-Dimethylpyrazol-1-yl)methyl]-N-[4-(ethylsulfamoyl)phenyl]furan-2-carboxamide

CAS 514841-03-3C₁₉H₂₂N₄O₄S

5-[(4-Chloropyrazol-1-yl)methyl]-N-(2,5-dichlorophenyl)furan-2-carboxamide chemical structure, C15H10Cl3N3O2, CAS 515150-41-1

5-[(4-Chloropyrazol-1-yl)methyl]-N-(2,5-dichlorophenyl)furan-2-carboxamide

CAS 515150-41-1C₁₅H₁₀Cl₃N₃O₂

4-[({5-[(4-Chloro-3,5-dimethyl-1H-pyrazol-1-yl)methyl]furan-2-yl}carbonyl)amino]benzoic acid chemical structure, C18H16ClN3O4, CAS 515120-84-0

4-[({5-[(4-Chloro-3,5-dimethyl-1H-pyrazol-1-yl)methyl]furan-2-yl}carbonyl)amino]benzoic acid

CAS 515120-84-0C₁₈H₁₆ClN₃O₄

5-[(4-Chloro-3,5-dimethylpyrazol-1-yl)methyl]-N-(2-iodophenyl)furan-2-carboxamide chemical structure, C17H15ClIN3O2, CAS 492423-02-6

5-[(4-Chloro-3,5-dimethylpyrazol-1-yl)methyl]-N-(2-iodophenyl)furan-2-carboxamide

CAS 492423-02-6C₁₇H₁₅ClIN₃O₂

5-[(4-Bromopyrazol-1-yl)methyl]-N-[3-(trifluoromethyl)phenyl]furan-2-carboxamide chemical structure, C16H11BrF3N3O2, CAS 957310-63-3

5-[(4-Bromopyrazol-1-yl)methyl]-N-[3-(trifluoromethyl)phenyl]furan-2-carboxamide

CAS 957310-63-3C₁₆H₁₁BrF₃N₃O₂

5-[(4-Bromo-3,5-dimethylpyrazol-1-yl)methyl]-N-(3,4,5-trimethoxyphenyl)furan-2-carboxamide chemical structure, C20H22BrN3O5, CAS 313272-63-8

5-[(4-Bromo-3,5-dimethylpyrazol-1-yl)methyl]-N-(3,4,5-trimethoxyphenyl)furan-2-carboxamide

CAS 313272-63-8C₂₀H₂₂BrN₃O₅

N-(2-Chlorophenyl)-5-[(4-nitropyrazol-1-yl)methyl]furan-2-carboxamide chemical structure, C15H11ClN4O4, CAS 514841-61-3

N-(2-Chlorophenyl)-5-[(4-nitropyrazol-1-yl)methyl]furan-2-carboxamide

CAS 514841-61-3C₁₅H₁₁ClN₄O₄

5-[(4-Bromo-1H-pyrazol-1-yl)methyl]-N-{4-[(ethylamino)sulfonyl]phenyl}-2-furamide chemical structure, C17H17BrN4O4S, CAS 515149-04-9

5-[(4-Bromo-1H-pyrazol-1-yl)methyl]-N-{4-[(ethylamino)sulfonyl]phenyl}-2-furamide

CAS 515149-04-9C₁₇H₁₇BrN₄O₄S

5-[(4-Chloro-1H-pyrazol-1-yl)methyl]-N-(2,6-dimethylphenyl)-2-furamide chemical structure, C17H16ClN3O2, CAS 515176-22-4

5-[(4-Chloro-1H-pyrazol-1-yl)methyl]-N-(2,6-dimethylphenyl)-2-furamide

CAS 515176-22-4C₁₇H₁₆ClN₃O₂

5-[(4-Bromo-3,5-dimethyl-1H-pyrazol-1-yl)methyl]-N-[2-(methylsulfanyl)phenyl]furan-2-carboxamide chemical structure, C18H18BrN3O2S, CAS 515151-46-9

5-[(4-Bromo-3,5-dimethyl-1H-pyrazol-1-yl)methyl]-N-[2-(methylsulfanyl)phenyl]furan-2-carboxamide

CAS 515151-46-9C₁₈H₁₈BrN₃O₂S

N-{4-[Acetyl(methyl)amino]phenyl}-5-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]-2-furamide chemical structure, C20H22N4O3, CAS 515150-28-4

N-{4-[Acetyl(methyl)amino]phenyl}-5-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]-2-furamide

CAS 515150-28-4C₂₀H₂₂N₄O₃