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Murcko scaffold

Ring system with 3 rings and 20 atoms

61 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
61
With full pages
7
Scaffold SMILES

O=C(Nc1ccccc1)c1ccc(Cn2cccn2)o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1ccc(Cn2cccn2)o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 61 of 61 chemicals

N-(5-tert-Butyl-2-methoxyphenyl)-5-[(4-chloro-3,5-dimethylpyrazol-1-yl)methyl]furan-2-carboxamide chemical structure, C22H26ClN3O3, CAS 491830-90-1
N-(5-tert-Butyl-2-methoxyphenyl)-5-[(4-chloro-3,5-dimethylpyrazol-1-yl)methyl]furan-2-carboxamide
CAS 491830-90-1C22H26ClN3O3
N-(2,5-Difluorophenyl)-5-[(3,5-dimethylpyrazol-1-yl)methyl]furan-2-carboxamide chemical structure, C17H15F2N3O2, CAS 514856-12-3
N-(2,5-Difluorophenyl)-5-[(3,5-dimethylpyrazol-1-yl)methyl]furan-2-carboxamide
CAS 514856-12-3C17H15F2N3O2
N-(2-Carbamoylphenyl)-5-[(4-chloro-5-methyl-3-nitropyrazol-1-yl)methyl]furan-2-carboxamide chemical structure, C17H14ClN5O5, CAS 514839-96-4
N-(2-Carbamoylphenyl)-5-[(4-chloro-5-methyl-3-nitropyrazol-1-yl)methyl]furan-2-carboxamide
CAS 514839-96-4C17H14ClN5O5
5-[(3,5-Dimethylpyrazol-1-yl)methyl]-N-[4-(methylsulfamoyl)phenyl]furan-2-carboxamide chemical structure, C18H20N4O4S, CAS 515151-69-6
5-[(3,5-Dimethylpyrazol-1-yl)methyl]-N-[4-(methylsulfamoyl)phenyl]furan-2-carboxamide
CAS 515151-69-6C18H20N4O4S
5-[(3,5-Dimethylpyrazol-1-yl)methyl]-N-(2-methoxyphenyl)furan-2-carboxamide chemical structure, C18H19N3O3, CAS 514843-51-7
5-[(3,5-Dimethylpyrazol-1-yl)methyl]-N-(2-methoxyphenyl)furan-2-carboxamide
CAS 514843-51-7C18H19N3O3
5-[(4-Chloro-3,5-dimethylpyrazol-1-yl)methyl]-N-(2,5-dimethoxyphenyl)furan-2-carboxamide chemical structure, C19H20ClN3O4, CAS 515831-40-0
5-[(4-Chloro-3,5-dimethylpyrazol-1-yl)methyl]-N-(2,5-dimethoxyphenyl)furan-2-carboxamide
CAS 515831-40-0C19H20ClN3O4
3-({5-[(4-Chloro-3,5-dimethyl-1H-pyrazol-1-yl)methyl]-2-furoyl}amino)-4-methylbenzoic acid chemical structure, C19H18ClN3O4, CAS 514817-95-9
3-({5-[(4-Chloro-3,5-dimethyl-1H-pyrazol-1-yl)methyl]-2-furoyl}amino)-4-methylbenzoic acid
CAS 514817-95-9C19H18ClN3O4
N-(3-Fluorophenyl)-5-[(4-nitropyrazol-1-yl)methyl]furan-2-carboxamide chemical structure, C15H11FN4O4, CAS 515150-63-7
N-(3-Fluorophenyl)-5-[(4-nitropyrazol-1-yl)methyl]furan-2-carboxamide
CAS 515150-63-7C15H11FN4O4
N-(4-Methoxy-2-methylphenyl)-5-[(4-nitropyrazol-1-yl)methyl]furan-2-carboxamide chemical structure, C17H16N4O5, CAS 515149-97-0
N-(4-Methoxy-2-methylphenyl)-5-[(4-nitropyrazol-1-yl)methyl]furan-2-carboxamide
CAS 515149-97-0C17H16N4O5
5-[(4-Chloropyrazol-1-yl)methyl]-N-[4-chloro-3-(trifluoromethyl)phenyl]furan-2-carboxamide chemical structure, C16H10Cl2F3N3O2, CAS 515122-69-7
5-[(4-Chloropyrazol-1-yl)methyl]-N-[4-chloro-3-(trifluoromethyl)phenyl]furan-2-carboxamide
CAS 515122-69-7C16H10Cl2F3N3O2
5-[(4-Chloro-3,5-dimethylpyrazol-1-yl)methyl]-N-(4-methoxy-2-nitrophenyl)furan-2-carboxamide chemical structure, C18H17ClN4O5, CAS 489408-41-5
5-[(4-Chloro-3,5-dimethylpyrazol-1-yl)methyl]-N-(4-methoxy-2-nitrophenyl)furan-2-carboxamide
CAS 489408-41-5C18H17ClN4O5
5-({4-Chloro-3-nitro-5-methyl-1H-pyrazol-1-yl}methyl)-N-(4-methylphenyl)-2-furamide chemical structure, C17H15ClN4O4, CAS 515177-51-2
5-({4-Chloro-3-nitro-5-methyl-1H-pyrazol-1-yl}methyl)-N-(4-methylphenyl)-2-furamide
CAS 515177-51-2C17H15ClN4O4
N-{4-Ethoxy-2-nitrophenyl}-5-({4-nitro-1H-pyrazol-1-yl}methyl)-2-furamide chemical structure, C17H15N5O7, CAS 489409-02-1
N-{4-Ethoxy-2-nitrophenyl}-5-({4-nitro-1H-pyrazol-1-yl}methyl)-2-furamide
CAS 489409-02-1C17H15N5O7