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Murcko scaffold

1',3'-Dihydrospiro[imidazolidine-4,2'-indene]-2,5-dione scaffold

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
7
With full pages
1
Scaffold SMILES

O=C1NC(=O)C2(Cc3ccccc3C2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1',3'-Dihydrospiro[imidazolidine-4,2'-indene]-2,5-dione page
Murcko scaffold O=C1NC(=O)C2(Cc3ccccc3C2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

1',3'-Dihydrospiro[imidazolidine-4,2'-indene]-2,5-dione chemical structure, C11H10N2O2, CAS 27473-61-6
1',3'-Dihydrospiro[imidazolidine-4,2'-indene]-2,5-dione
CAS 27473-61-6C11H10N2O2
Spiro(5-nitroindane)-2,5'-hydantoin chemical structure, C11H9N3O4, CAS 33584-66-6
Spiro(5-nitroindane)-2,5'-hydantoin
CAS 33584-66-6C11H9N3O4
5'-Amino-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-2,5-dione chemical structure, C11H11N3O2, CAS 33584-67-7
5'-Amino-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-2,5-dione
CAS 33584-67-7C11H11N3O2
5'-Bromo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-2,5-dione chemical structure, C11H9BrN2O2, CAS 33584-72-4
5'-Bromo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-2,5-dione
CAS 33584-72-4C11H9BrN2O2
Methyl 2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-3'-carboxylate chemical structure, C13H12N2O4, CAS 2118257-67-1
Methyl 2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-3'-carboxylate
CAS 2118257-67-1C13H12N2O4
(S)-5'-Amino-3-methyl-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-2,5-dione chemical structure, C12H13N3O2, CAS 957130-50-6
(S)-5'-Amino-3-methyl-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-2,5-dione
CAS 957130-50-6C12H13N3O2
(R)-3-Methyl-5'-nitro-spiro[imidazolidine-4,2'-indane]-2,5-dione chemical structure, C12H11N3O4, CAS 917084-92-5
(R)-3-Methyl-5'-nitro-spiro[imidazolidine-4,2'-indane]-2,5-dione
CAS 917084-92-5C12H11N3O4