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Murcko scaffold

1,3-Dihydrospiro[indene-2,3'-pyrrolidine] scaffold

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
13
Chemicals
15
With full pages
1
Scaffold SMILES

c1ccc2c(c1)CC1(CCNC1)C2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,3-Dihydrospiro[indene-2,3'-pyrrolidine] page
Murcko scaffold c1ccc2c(c1)CC1(CCNC1)C2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

1,3-Dihydrospiro[indene-2,3'-pyrrolidine] chemical structure, C12H15N, CAS 183-20-0
1,3-Dihydrospiro[indene-2,3'-pyrrolidine]
CAS 183-20-0C12H15N
1,3-Dihydrospiro[indene-2,3'-pyrrolidine]-5'-carboxylic acid chemical structure, C13H15NO2, CAS 734532-12-8
1,3-Dihydrospiro[indene-2,3'-pyrrolidine]-5'-carboxylic acid
CAS 734532-12-8C13H15NO2
1'-(tert-Butoxycarbonyl)-1,3-dihydrospiro[indene-2,3'-pyrrolidine]-5'-carboxylic acid chemical structure, C18H23NO4, CAS 663956-58-9
1'-(tert-Butoxycarbonyl)-1,3-dihydrospiro[indene-2,3'-pyrrolidine]-5'-carboxylic acid
CAS 663956-58-9C18H23NO4
1,3-Dihydrospiro[indene-2,3'-pyrrolidine]-1'-carboxamide chemical structure, C13H16N2O, CAS 2093630-74-9
1,3-Dihydrospiro[indene-2,3'-pyrrolidine]-1'-carboxamide
CAS 2093630-74-9C13H16N2O
1,3-Dihydrospiro[indene-2,3'-pyrrolidine] hydrochloride chemical structure, C12H16ClN, CAS 2097996-29-5
1,3-Dihydrospiro[indene-2,3'-pyrrolidine] hydrochloride
CAS 2097996-29-5C12H16ClN
5-Bromo-1,3-dihydrospiro[indene-2,3'-pyrrolidine] chemical structure, C12H14BrN, CAS 1934754-57-0
5-Bromo-1,3-dihydrospiro[indene-2,3'-pyrrolidine]
CAS 1934754-57-0C12H14BrN
tert-Butyl 5-amino-1,3-dihydrospiro[indene-2,3'-pyrrolidine]-1'-carboxylate chemical structure, C17H24N2O2, CAS 1934888-66-0
tert-Butyl 5-amino-1,3-dihydrospiro[indene-2,3'-pyrrolidine]-1'-carboxylate
CAS 1934888-66-0C17H24N2O2
Methyl 1,3-dihydrospiro[indene-2,3'-pyrrolidine]-5-carboxylate chemical structure, C14H17NO2, CAS 2170211-02-4
Methyl 1,3-dihydrospiro[indene-2,3'-pyrrolidine]-5-carboxylate
CAS 2170211-02-4C14H17NO2
1-Spiro[1,3-dihydroindene-2,3'-pyrrolidine]-1'-ylprop-2-en-1-one chemical structure, C15H17NO, CAS 2176573-20-7
1-Spiro[1,3-dihydroindene-2,3'-pyrrolidine]-1'-ylprop-2-en-1-one
CAS 2176573-20-7C15H17NO
Methyl 1,3-dihydrospiro[indene-2,3'-pyrrolidine]-4-carboxylate chemical structure, C14H17NO2, CAS 2223001-36-1
Methyl 1,3-dihydrospiro[indene-2,3'-pyrrolidine]-4-carboxylate
CAS 2223001-36-1C14H17NO2
Methyl (S)-1,3-dihydrospiro[indene-2,3'-pyrrolidine]-5-carboxylate chemical structure, C14H17NO2, CAS 2170211-08-0
Methyl (S)-1,3-dihydrospiro[indene-2,3'-pyrrolidine]-5-carboxylate
CAS 2170211-08-0C14H17NO2
Methyl (S)-1'-methyl-1,3-dihydrospiro[indene-2,3'-pyrrolidine]-5-carboxylate chemical structure, C15H19NO2, CAS 2170211-09-1
Methyl (S)-1'-methyl-1,3-dihydrospiro[indene-2,3'-pyrrolidine]-5-carboxylate
CAS 2170211-09-1C15H19NO2
Methyl (R)-1'-methyl-1,3-dihydrospiro[indene-2,3'-pyrrolidine]-5-carboxylate chemical structure, C15H19NO2, CAS 2170211-07-9
Methyl (R)-1'-methyl-1,3-dihydrospiro[indene-2,3'-pyrrolidine]-5-carboxylate
CAS 2170211-07-9C15H19NO2
Methyl (R)-1,3-dihydrospiro[indene-2,3'-pyrrolidine]-5-carboxylate chemical structure, C14H17NO2, CAS 2170211-06-8
Methyl (R)-1,3-dihydrospiro[indene-2,3'-pyrrolidine]-5-carboxylate
CAS 2170211-06-8C14H17NO2
4'-Fluoro-1,3-dihydrospiro[indene-2,3'-pyrrolidine]-4'-carboxylic acid chemical structure, C13H14FNO2, CAS 2005524-96-7
4'-Fluoro-1,3-dihydrospiro[indene-2,3'-pyrrolidine]-4'-carboxylic acid
CAS 2005524-96-7C13H14FNO2