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Murcko scaffold

1,3-Cyclohexanedione, 2,2'-(phenylmethylene)bis- scaffold

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
11
With full pages
6
Scaffold SMILES

O=C1CCCC(=O)C1C(c1ccccc1)C1C(=O)CCCC1=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,3-Cyclohexanedione, 2,2'-(phenylmethylene)bis- page
Murcko scaffold O=C1CCCC(=O)C1C(c1ccccc1)C1C(=O)CCCC1=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

2,2'-{[4-(Propan-2-yl)phenyl]methylene}bis(5,5-dimethylcyclohexane-1,3-dione) chemical structure, C26H34O4, CAS 500341-71-9
2,2'-{[4-(Propan-2-yl)phenyl]methylene}bis(5,5-dimethylcyclohexane-1,3-dione)
CAS 500341-71-9C26H34O4
2-[(4,4-Dimethyl-2,6-dioxo-cyclohexyl)-(4-methoxyphenyl)methyl]-5,5-dimethyl-cyclohexane-1,3-dione chemical structure, C24H30O5, CAS 19419-24-0
2-[(4,4-Dimethyl-2,6-dioxo-cyclohexyl)-(4-methoxyphenyl)methyl]-5,5-dimethyl-cyclohexane-1,3-dione
CAS 19419-24-0C24H30O5
2,2'-(Phenylmethylene)bis(5,5-dimethylcyclohexane-1,3-dione) chemical structure, C23H28O4, CAS 19419-23-9
2,2'-(Phenylmethylene)bis(5,5-dimethylcyclohexane-1,3-dione)
CAS 19419-23-9C23H28O4
2-[(4,4-Dimethyl-2,6-dioxocyclohexyl)-(4-hydroxy-3-methoxyphenyl)methyl]-5,5-dimethylcyclohexane-1,3-dione chemical structure, C24H30O6, CAS 7506-25-4
2-[(4,4-Dimethyl-2,6-dioxocyclohexyl)-(4-hydroxy-3-methoxyphenyl)methyl]-5,5-dimethylcyclohexane-1,3-dione
CAS 7506-25-4C24H30O6
2-[(4,4-Dimethyl-2,6-dioxocyclohexyl)-(3-methoxyphenyl)methyl]-5,5-dimethylcyclohexane-1,3-dione chemical structure, C24H30O5, CAS 313959-15-8
2-[(4,4-Dimethyl-2,6-dioxocyclohexyl)-(3-methoxyphenyl)methyl]-5,5-dimethylcyclohexane-1,3-dione
CAS 313959-15-8C24H30O5
2-[(4,4-Dimethyl-2,6-dioxocyclohexyl)-(4-fluorophenyl)methyl]-5,5-dimethylcyclohexane-1,3-dione chemical structure, C23H27FO4, CAS 414899-10-8
2-[(4,4-Dimethyl-2,6-dioxocyclohexyl)-(4-fluorophenyl)methyl]-5,5-dimethylcyclohexane-1,3-dione
CAS 414899-10-8C23H27FO4
2-[[4-(Dimethylamino)phenyl](4,4-dimethyl-2,6-dioxocyclohexyl)methyl]-5,5-dimethyl-1,3-cyclohexanedione chemical structure, C25H33NO4, CAS 33742-94-8
2-[[4-(Dimethylamino)phenyl](4,4-dimethyl-2,6-dioxocyclohexyl)methyl]-5,5-dimethyl-1,3-cyclohexanedione
CAS 33742-94-8C25H33NO4
1,3-Cyclohexanedione, 2,2'-[(2-nitrophenyl)methylene]bis[5,5-dimethyl- chemical structure, C23H27NO6, CAS 183737-77-1
1,3-Cyclohexanedione, 2,2'-[(2-nitrophenyl)methylene]bis[5,5-dimethyl-
CAS 183737-77-1C23H27NO6
2-[(4-Chlorophenyl)-(4,4-dimethyl-2,6-dioxocyclohexyl)methyl]-5,5-dimethylcyclohexane-1,3-dione chemical structure, C23H27ClO4, CAS 329734-80-7
2-[(4-Chlorophenyl)-(4,4-dimethyl-2,6-dioxocyclohexyl)methyl]-5,5-dimethylcyclohexane-1,3-dione
CAS 329734-80-7C23H27ClO4
3-Hydroxy-2-((2-hydroxy-4,4-dimethyl-6-oxo-1-cyclohexen-1-yl){4-nitrophenyl}methyl)-5,5-dimethyl-2-cyclohexen-1-one chemical structure, C23H27NO6, CAS 329734-82-9
3-Hydroxy-2-((2-hydroxy-4,4-dimethyl-6-oxo-1-cyclohexen-1-yl){4-nitrophenyl}methyl)-5,5-dimethyl-2-cyclohexen-1-one
CAS 329734-82-9C23H27NO6
1,3-Cyclohexanedione, 2,2'-(phenylmethylene)bis- chemical structure, C19H20O4, CAS 55771-10-3
1,3-Cyclohexanedione, 2,2'-(phenylmethylene)bis-
CAS 55771-10-3C19H20O4