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Murcko scaffold

Ring system with 2 rings and 23 atoms

19 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
23
Chemicals
19
With full pages
17
Scaffold SMILES

O=C(CNC(=O)c1ccccc1)NN=CC=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CNC(=O)c1ccccc1)NN=CC=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

3-Chloro-N-[2-oxo-2-[(2E)-2-[(E)-3-phenylprop-2-enylidene]hydrazinyl]ethyl]benzamide chemical structure, C18H16ClN3O2, CAS 5468-09-7
3-Chloro-N-[2-oxo-2-[(2E)-2-[(E)-3-phenylprop-2-enylidene]hydrazinyl]ethyl]benzamide
CAS 5468-09-7C18H16ClN3O2
N-(2-Oxo-2-{(2E)-2-[(2E)-3-phenyl-2-propenylidene]hydrazino}ethyl)-4-propoxybenzamide chemical structure, C21H23N3O3, CAS 767312-04-9
N-(2-Oxo-2-{(2E)-2-[(2E)-3-phenyl-2-propenylidene]hydrazino}ethyl)-4-propoxybenzamide
CAS 767312-04-9C21H23N3O3
3,4-Dimethoxy-N-(2-oxo-2-(2-(3-phenyl-2-propenylidene)hydrazino)ethyl)benzamide chemical structure, C20H21N3O4, CAS 325483-81-6
3,4-Dimethoxy-N-(2-oxo-2-(2-(3-phenyl-2-propenylidene)hydrazino)ethyl)benzamide
CAS 325483-81-6C20H21N3O4
2-Iodo-N-(2-oxo-2-(2-(3-phenyl-2-propenylidene)hydrazino)ethyl)benzamide chemical structure, C18H16IN3O2, CAS 769146-87-4
2-Iodo-N-(2-oxo-2-(2-(3-phenyl-2-propenylidene)hydrazino)ethyl)benzamide
CAS 769146-87-4C18H16IN3O2
N-(2-(2-(2-ME-3-Phenyl-2-propenylidene)hydrazino)-2-oxoethyl)-4-propoxybenzamide chemical structure, C22H25N3O3, CAS 769150-16-5
N-(2-(2-(2-ME-3-Phenyl-2-propenylidene)hydrazino)-2-oxoethyl)-4-propoxybenzamide
CAS 769150-16-5C22H25N3O3
3,4-Dichloro-N-(2-(2-(2-ME-3-PH-2-propenylidene)hydrazino)-2-oxoethyl)benzamide chemical structure, C19H17Cl2N3O2, CAS 769149-64-6
3,4-Dichloro-N-(2-(2-(2-ME-3-PH-2-propenylidene)hydrazino)-2-oxoethyl)benzamide
CAS 769149-64-6C19H17Cl2N3O2
4-ME-N-(2-(2-(2-Methyl-3-phenyl-2-propenylidene)hydrazino)-2-oxoethyl)benzamide chemical structure, C20H21N3O2, CAS 769149-60-2
4-ME-N-(2-(2-(2-Methyl-3-phenyl-2-propenylidene)hydrazino)-2-oxoethyl)benzamide
CAS 769149-60-2C20H21N3O2
3-BR-N-(2-(2-(2-Methyl-3-phenyl-2-propenylidene)hydrazino)-2-oxoethyl)benzamide chemical structure, C19H18BrN3O2, CAS 769149-47-5
3-BR-N-(2-(2-(2-Methyl-3-phenyl-2-propenylidene)hydrazino)-2-oxoethyl)benzamide
CAS 769149-47-5C19H18BrN3O2
4-F-N-(2-(2-(2-Methyl-3-phenyl-2-propenylidene)hydrazino)-2-oxoethyl)benzamide chemical structure, C19H18FN3O2, CAS 769149-13-5
4-F-N-(2-(2-(2-Methyl-3-phenyl-2-propenylidene)hydrazino)-2-oxoethyl)benzamide
CAS 769149-13-5C19H18FN3O2
3,4-Dimethoxy-N-(2-(2-(2-ME-3-PH-2-propenylidene)hydrazino)-2-oxoethyl)benzamide chemical structure, C21H23N3O4, CAS 339005-18-4
3,4-Dimethoxy-N-(2-(2-(2-ME-3-PH-2-propenylidene)hydrazino)-2-oxoethyl)benzamide
CAS 339005-18-4C21H23N3O4
2-I-N-(2-(2-(2-Methyl-3-phenyl-2-propenylidene)hydrazino)-2-oxoethyl)benzamide chemical structure, C19H18IN3O2, CAS 764656-81-7
2-I-N-(2-(2-(2-Methyl-3-phenyl-2-propenylidene)hydrazino)-2-oxoethyl)benzamide
CAS 764656-81-7C19H18IN3O2
4-Methyl-N-(2-oxo-2-(2-(3-phenyl-2-propenylidene)hydrazino)ethyl)benzamide chemical structure, C19H19N3O2, CAS 769142-55-4
4-Methyl-N-(2-oxo-2-(2-(3-phenyl-2-propenylidene)hydrazino)ethyl)benzamide
CAS 769142-55-4C19H19N3O2
2-Methyl-N-(2-oxo-2-(2-(3-phenyl-2-propenylidene)hydrazino)ethyl)benzamide chemical structure, C19H19N3O2, CAS 444567-69-5
2-Methyl-N-(2-oxo-2-(2-(3-phenyl-2-propenylidene)hydrazino)ethyl)benzamide
CAS 444567-69-5C19H19N3O2
3-Bromo-N-(2-oxo-2-(2-(3-phenyl-2-propenylidene)hydrazino)ethyl)benzamide chemical structure, C18H16BrN3O2, CAS 769143-38-6
3-Bromo-N-(2-oxo-2-(2-(3-phenyl-2-propenylidene)hydrazino)ethyl)benzamide
CAS 769143-38-6C18H16BrN3O2
4-Methoxy-N-(2-oxo-2-(2-(3-phenyl-2-propenylidene)hydrazino)ethyl)benzamide chemical structure, C19H19N3O3, CAS 767310-69-0
4-Methoxy-N-(2-oxo-2-(2-(3-phenyl-2-propenylidene)hydrazino)ethyl)benzamide
CAS 767310-69-0C19H19N3O3
3-Methyl-N-(2-(2-(2-methyl-3-PH-2-propenylidene)hydrazino)-2-oxoethyl)benzamide chemical structure, C20H21N3O2, CAS 881683-54-1
3-Methyl-N-(2-(2-(2-methyl-3-PH-2-propenylidene)hydrazino)-2-oxoethyl)benzamide
CAS 881683-54-1C20H21N3O2
4-CL-N-(2-(2-(2-Methyl-3-phenyl-2-propenylidene)hydrazino)-2-oxoethyl)benzamide chemical structure, C19H18ClN3O2, CAS 339084-81-0
4-CL-N-(2-(2-(2-Methyl-3-phenyl-2-propenylidene)hydrazino)-2-oxoethyl)benzamide
CAS 339084-81-0C19H18ClN3O2
3-CL-N-(2-(2-(2-Methyl-3-phenyl-2-propenylidene)hydrazino)-2-oxoethyl)benzamide chemical structure, C19H18ClN3O2, CAS 881664-10-4
3-CL-N-(2-(2-(2-Methyl-3-phenyl-2-propenylidene)hydrazino)-2-oxoethyl)benzamide
CAS 881664-10-4C19H18ClN3O2
L-Methionine, N-benzoyl-, (3-phenyl-2-propenylidene)hydrazide chemical structure, C21H23N3O2S, CAS 479347-90-5
L-Methionine, N-benzoyl-, (3-phenyl-2-propenylidene)hydrazide
CAS 479347-90-5C21H23N3O2S