Murcko scaffold
Ring system with 2 rings and 23 atoms
144 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 23
- Chemicals
- 144
- With full pages
- 15
Scaffold SMILES
O=C(CCc1ccccc1)NCC(=O)NCCc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 144 chemicals
Ethyl N-(3-(bis(2-chloroethyl)amino)-N-(N-(4-fluoro-3-phenyl-L-alanyl)glycyl)-3-phenyl-L-alanyl)-L-norvalinate
CAS 32976-86-6C31H42Cl2FN5O5
Tyrosyl-arginyl-phenylalanyl-lysinamide
CAS 118476-85-0C30H45N9O5
Deltorphin II, ala(2)-
CAS 122752-16-3C38H54N8O10
F-Chemotactic peptide
CAS 71901-21-8C43H65N7O9
Tyrosyl-isoleucyl-phenylalanyl-valine
CAS 93772-67-9C29H40N4O6
Tyrosyl-arginyl-phenylalanyl-glycinamide
CAS 100304-60-7C26H36N8O5
Tyrosyl-arginyl-phenylalanyl-sarcosine
CAS 90549-86-3C27H37N7O6
Tyrosyl-arginyl-phenylalanyl-beta-alaninamide
CAS 138228-38-3C27H38N8O5
Tyrosyl-alanyl-phenylalanyl-glycinamide
CAS 78700-75-1C23H29N5O5
Tyrosyl-methionyl-phenylalanyl-glycinamide
CAS 87619-62-3C25H33N5O5S
Tyrosyl-arginyl-phenylalanyl-glycine
CAS 90549-83-0C26H35N7O6
Tyrosyl-arginyl-phenylalanyl-glycine ethyl ester
CAS 90549-84-1C28H39N7O6
Ethyltyrosyl-arginyl-phenylalanyl-glycine ethyl ester
CAS 92759-01-8C28H39N7O6
Historphin
CAS 105250-85-9C24H29N5O7
Asparaginyl-seryl-phenylalanyl-arginyl-tyrosinamide
CAS 151937-05-2C31H44N10O8
Enkephalin, N-cyclo-leu(5)-
CAS 75975-40-5C28H35N5O6
Deltorphin II, ile(5,6)-
CAS 138166-93-5C40H58N8O10
![2-[[2-[[2-[(2-Amino-3-phenylpropanoyl)amino]acetyl]amino]-3-phenylpropanoyl]amino]acetic acid chemical structure, C22H26N4O5, CAS 59005-83-3](/s/QVOBNSFUVPLVPE-UHFFFAOYSA-N.svg)
2-[[2-[[2-[(2-Amino-3-phenylpropanoyl)amino]acetyl]amino]-3-phenylpropanoyl]amino]acetic acid
CAS 59005-83-3C22H26N4O5
Vesicular stomatitis virus nucleoprotein (52-59)
CAS 132326-74-0C44H66N12O12
H-GLY-ILE-LEU-GLY-PHE-VAL-PHE-THR-LEU-OH
CAS 141368-69-6C49H75N9O11
Phenylalanyl-valyl-phenylalanyl-psi(methylamino)leucyl-glutamyl-isoleucineamide
CAS 152017-02-2C40H61N7O7
H-Tyrosyl-cyclo(cysteinyl-phenylalanyl-penicillaminyl)-OH
CAS 117550-12-6C26H34N4O6S2
Tyrosyl-arginyl-phenylalanyl-alanine
CAS 96425-84-2C27H37N7O6
Tyrosyl-alanyl-delta-phenylalanyl-glycinamide
CAS 97992-01-3C23H29N5O5
- Tyrosyl-alanyl-phenylalanyl-glycine78700-74-0C23H28N4O6
- LCMV gp33-41151705-84-9C48H73N11O13S
- H-Lys-Ala-Val-Tyr-Asn-Phe-Ala-Thr-Cys-OH161928-86-5C46H69N11O13S
- L-Phenylalaninamide, L-tyrosyl-D-alanyl-80475-47-4C21H26N4O4
- Tyr-Ser-Phe144678-04-6C21H25N3O6
- [Dmt1]DALDA255861-98-4C32H49N9O5
- H-Ile-Tyr-Ser-Tyr-OH231282-43-2C27H36N4O8
- Nerfilin I165189-77-5C28H37N3O5
- L-Lysinamide, L-phenylalanyl-D-arginyl-L-phenylalanyl-736992-19-1C30H45N9O4
- 6 suppliersDeltorphin I, ala(2)-122752-15-2C37H52N8O10
- 2 suppliersMLCK inhibitor peptide 18224579-74-2C60H105N23O11
- H-Arg-Tyr-D-Arg-Phe-D-Ala-NH2176448-03-6C33H50N12O6
- 4-Fluoro-N-methyl-L-phenylalanyl-N-methyl-L-valyl-3-(1,1-dimethylethyl)-N-ethyl-L-tyrosinamide287206-61-5C31H45FN4O4
- H-Met-Tyr-Gly-Phe-Gly-Gly-OH496854-25-2C29H38N6O8S
- L-Threonine, L-seryl-L-alanyl-L-seryl-L-tyrosyl-L-arginyl-L-tyrosyl-164982-81-4C37H54N10O13
- L-Phenylalanine, L-phenylalanylglycyl-87742-85-6C20H23N3O4
- Glycine, L-phenylalanyl-L-lysyl-L-phenylalanyl-L-isoleucyl-532436-01-4C32H46N6O6
- Tyropeptin B402830-02-8C28H37N3O6
- H-Tyr(SO3H)-Ile-Tyr(SO3H)-Thr-Gln-OH179667-62-0C33H46N6O16S2
- Glycyl-L-phenylalanylglycyl-L-phenylalanine75853-31-5C22H26N4O5
- Tyropeptin A402830-01-7C28H37N3O6
- 12 suppliersElamipretide736992-21-5C32H49N9O5
- 1 suppliersH-Gly-asp-gly-arg-leu-tyr-ala-phe-gly-leu-NH2123374-34-5C49H74N14O13
- 1 suppliersAllatostatin IV123338-13-6C45H68N12O12
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(CNC(=O)OCc1ccccc1)NCCc1ccccc120 chemicals
O=C(CNC(=O)c1ccccc1)NN=CC=Cc1ccccc117 chemicals
O=C(COc1ccccc1)NCC(=O)NN=Cc1ccccc18 chemicals
O=C(NCCCCCNC(=O)c1ccccc1)c1ccccc16 chemicals
O=C(COc1ccccc1)NCCCNC(=O)c1cccnc16 chemicals
O=C(COC(=O)CCOc1ccccc1)NCc1ccccc15 chemicals
O=C(CCCCCCCCc1ccccc1)c1ccccc14 chemicals
O=C(OCCOCCOC(=O)c1ccccc1)c1ccccc14 chemicals
O=C(CCCC(=O)OCc1ccccc1)OCc1ccccc14 chemicals
O=C(NCCNCCCOc1ccccc1)N1CCOCC13 chemicals
O=C(CCC(=O)Nc1ccccc1)NNC(=O)NC1CCCCC13 chemicals
O=C(CCS(=O)(=O)c1ccccc1)NNC(=O)CSc1ccccc13 chemicals