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Murcko scaffold

Ring system with 2 rings and 23 atoms

99 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
23
Chemicals
99
With full pages
20
Scaffold SMILES

O=C(CNC(=O)OCc1ccccc1)NCCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CNC(=O)OCc1ccccc1)NCCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 99 chemicals

Carbobenzoxyglycylphenylalanine chemical structure, C19H20N2O5, CAS 54885-66-4
Carbobenzoxyglycylphenylalanine
CAS 54885-66-4C19H20N2O5
Mdl-28170 chemical structure, C22H26N2O4, CAS 756485-04-8
Mdl-28170
CAS 756485-04-8C22H26N2O4
3-Phenyl-N-(N-((phenylmethoxy)carbonyl)-L-alpha-glutamyl)-L-alanine chemical structure, C22H24N2O7, CAS 987-84-8
3-Phenyl-N-(N-((phenylmethoxy)carbonyl)-L-alpha-glutamyl)-L-alanine
CAS 987-84-8C22H24N2O7
Carbobenzoxyglycylphenylalanine amide chemical structure, C19H21N3O4, CAS 5513-69-9
Carbobenzoxyglycylphenylalanine amide
CAS 5513-69-9C19H21N3O4
N-((Phenylmethoxy)carbonyl)-L-alpha-glutamyl-L-tyrosine chemical structure, C22H24N2O8, CAS 988-75-0
N-((Phenylmethoxy)carbonyl)-L-alpha-glutamyl-L-tyrosine
CAS 988-75-0C22H24N2O8
N-(N-((Benzyloxy)carbonyl)-L-valyl)-L-tyrosinohydrazide chemical structure, C22H28N4O5, CAS 5992-90-5
N-(N-((Benzyloxy)carbonyl)-L-valyl)-L-tyrosinohydrazide
CAS 5992-90-5C22H28N4O5
(S)-2-((2S,3S)-2-(((Benzyloxy)carbonyl)amino)-3-methylpentanamido)-3-phenylpropanoic acid chemical structure, C23H28N2O5, CAS 13254-07-4
(S)-2-((2S,3S)-2-(((Benzyloxy)carbonyl)amino)-3-methylpentanamido)-3-phenylpropanoic acid
CAS 13254-07-4C23H28N2O5
Carbobenzoxy-glycyl-tyrosyl-glycine ethyl ester chemical structure, C23H27N3O7, CAS 3561-36-2
Carbobenzoxy-glycyl-tyrosyl-glycine ethyl ester
CAS 3561-36-2C23H27N3O7
Carbobenzyloxyleucyl-tyrosine chloromethyl ketone chemical structure, C24H29ClN2O5, CAS 56979-35-2
Carbobenzyloxyleucyl-tyrosine chloromethyl ketone
CAS 56979-35-2C24H29ClN2O5
Methyl 3-phenyl-2-[2-(phenylmethoxycarbonylamino)propanoylamino]propanoate chemical structure, C21H24N2O5, CAS 3235-14-1
Methyl 3-phenyl-2-[2-(phenylmethoxycarbonylamino)propanoylamino]propanoate
CAS 3235-14-1C21H24N2O5
Ethyl 2-[[3-phenyl-2-[[2-(phenylmethoxycarbonylamino)acetyl]amino]propanoyl]amino]acetate chemical structure, C23H27N3O6, CAS 2073-59-8
Ethyl 2-[[3-phenyl-2-[[2-(phenylmethoxycarbonylamino)acetyl]amino]propanoyl]amino]acetate
CAS 2073-59-8C23H27N3O6
Methyl 3-(4-hydroxyphenyl)-2-[2-(phenylmethoxycarbonylamino)propanoylamino]propanoate chemical structure, C21H24N2O6, CAS 17554-28-8
Methyl 3-(4-hydroxyphenyl)-2-[2-(phenylmethoxycarbonylamino)propanoylamino]propanoate
CAS 17554-28-8C21H24N2O6
Ethyl N-[(benzyloxy)carbonyl]glycyltyrosinate chemical structure, C21H24N2O6, CAS 3249-01-2
Ethyl N-[(benzyloxy)carbonyl]glycyltyrosinate
CAS 3249-01-2C21H24N2O6
Methyl N-[(benzyloxy)carbonyl]glycylphenylalaninate chemical structure, C20H22N2O5, CAS 6206-42-4
Methyl N-[(benzyloxy)carbonyl]glycylphenylalaninate
CAS 6206-42-4C20H22N2O5
3-Phenyl-2-[2-(phenylmethoxycarbonylamino)pentanoylamino]propanoic acid chemical structure, C22H26N2O5, CAS 63623-59-6
3-Phenyl-2-[2-(phenylmethoxycarbonylamino)pentanoylamino]propanoic acid
CAS 63623-59-6C22H26N2O5
Benzyl N-[1-[(1-carbamoyl-2-phenyl-ethyl)carbamoyl]butyl]carbamate chemical structure, C22H27N3O4, CAS 17337-71-2
Benzyl N-[1-[(1-carbamoyl-2-phenyl-ethyl)carbamoyl]butyl]carbamate
CAS 17337-71-2C22H27N3O4
2-[(3-Hydroxy-2-phenylmethoxycarbonylamino-butanoyl)amino]-3-phenyl-propanoic acid chemical structure, C21H24N2O6, CAS 19649-03-7
2-[(3-Hydroxy-2-phenylmethoxycarbonylamino-butanoyl)amino]-3-phenyl-propanoic acid
CAS 19649-03-7C21H24N2O6
Carbobenzyloxy-L-seryl-L-tyrosine chemical structure, C20H22N2O7, CAS 52885-18-4
Carbobenzyloxy-L-seryl-L-tyrosine
CAS 52885-18-4C20H22N2O7
3-(4-Hydroxyphenyl)-2-[[3-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]propanoic acid chemical structure, C23H28N2O6, CAS 13122-94-6
3-(4-Hydroxyphenyl)-2-[[3-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]propanoic acid
CAS 13122-94-6C23H28N2O6
N-[(Benzyloxy)carbonyl]leucyltyrosine chemical structure, C23H28N2O6, CAS 40908-35-8
N-[(Benzyloxy)carbonyl]leucyltyrosine
CAS 40908-35-8C23H28N2O6
2-[[2-[Methyl(phenylmethoxycarbonyl)amino]acetyl]amino]-3-phenylpropanoic acid chemical structure, C20H22N2O5, CAS 13716-75-1
2-[[2-[Methyl(phenylmethoxycarbonyl)amino]acetyl]amino]-3-phenylpropanoic acid
CAS 13716-75-1C20H22N2O5
Benzyl N-[2-[(1-hydrazinyl-1-oxo-3-phenylpropan-2-yl)amino]-2-oxoethyl]carbamate chemical structure, C19H22N4O4, CAS 17942-42-6
Benzyl N-[2-[(1-hydrazinyl-1-oxo-3-phenylpropan-2-yl)amino]-2-oxoethyl]carbamate
CAS 17942-42-6C19H22N4O4
L-Valine, N-(N-(4-hydroxy-1-oxo-5-((1-oxo-2-(((phenylmethoxy)carbonyl)amino)propyl)amino)-6-phenylhexyl)-L-valyl)-, methyl ester, (4S-(4R*,5R*(R*)))- chemical structure, C34H48N4O8, CAS 126380-02-7
L-Valine, N-(N-(4-hydroxy-1-oxo-5-((1-oxo-2-(((phenylmethoxy)carbonyl)amino)propyl)amino)-6-phenylhexyl)-L-valyl)-, methyl ester, (4S-(4R*,5R*(R*)))-
CAS 126380-02-7C34H48N4O8
N-Benzyloxycarbonyl-valyl-phenylalanine methyl ester chemical structure, C22H26N2O5, CAS 19542-51-9
N-Benzyloxycarbonyl-valyl-phenylalanine methyl ester
CAS 19542-51-9C22H26N2O5