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Murcko scaffold

Ring system with 2 rings and 13 atoms

64 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
64
With full pages
6
Scaffold SMILES

O=c1[nH]c(=S)ccn1C1CCCO1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]c(=S)ccn1C1CCCO1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 64 chemicals

Thymidine, 3'-deoxy-3'-fluoro-4-thio- chemical structure, C10H13FN2O3S, CAS 124903-20-4
Thymidine, 3'-deoxy-3'-fluoro-4-thio-
CAS 124903-20-4C10H13FN2O3S
3'-Deoxy-4-thiothymidine chemical structure, C10H14N2O3S, CAS 122568-03-0
3'-Deoxy-4-thiothymidine
CAS 122568-03-0C10H14N2O3S
3'-Azido-3'-deoxy-4-thiothymidine chemical structure, C10H13N5O3S, CAS 108441-45-8
3'-Azido-3'-deoxy-4-thiothymidine
CAS 108441-45-8C10H13N5O3S
2',3'-Dideoxy-4-thiouridine chemical structure, C9H12N2O3S, CAS 122568-04-1
2',3'-Dideoxy-4-thiouridine
CAS 122568-04-1C9H12N2O3S
3'-Azido-2',3'-dideoxy-4-thiouridine chemical structure, C9H11N5O3S, CAS 132739-16-3
3'-Azido-2',3'-dideoxy-4-thiouridine
CAS 132739-16-3C9H11N5O3S
4-Thiouridine chemical structure, C9H12N2O5S, CAS 13957-31-8
4-Thiouridine
CAS 13957-31-8C9H12N2O5S
4-Thiouridine triphosphate chemical structure, C9H15N2O14P3S, CAS 31556-28-2
4-Thiouridine triphosphate
CAS 31556-28-2C9H15N2O14P3S
Deoxy-4-thiothymidine chemical structure, C10H14N2O4S, CAS 7236-57-9
Deoxy-4-thiothymidine
CAS 7236-57-9C10H14N2O4S
Arabino-4-thiouridine chemical structure, C9H12N2O5S, CAS 32754-06-6
Arabino-4-thiouridine
CAS 32754-06-6C9H12N2O5S
4-Thio-2'-deoxyuridine chemical structure, C9H12N2O4S, CAS 5580-20-1
4-Thio-2'-deoxyuridine
CAS 5580-20-1C9H12N2O4S
5-Fluoro-4-thio-2'-deoxyuridylate chemical structure, C9H12FN2O7PS, CAS 114319-04-9
5-Fluoro-4-thio-2'-deoxyuridylate
CAS 114319-04-9C9H12FN2O7PS
3'-O-Acetyl-4-thiothymidine chemical structure, C12H16N2O5S, CAS 20188-76-5
3'-O-Acetyl-4-thiothymidine
CAS 20188-76-5C12H16N2O5S
[3,4-Diacetyloxy-5-(2-oxo-4-sulfanylidenepyrimidin-1-yl)oxolan-2-yl]methyl acetate chemical structure, C15H18N2O8S, CAS 25130-27-2
[3,4-Diacetyloxy-5-(2-oxo-4-sulfanylidenepyrimidin-1-yl)oxolan-2-yl]methyl acetate
CAS 25130-27-2C15H18N2O8S
5-Fluoro-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-sulfanylidenepyrimidin-2-one chemical structure, C9H11FN2O4S, CAS 5254-55-7
5-Fluoro-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-sulfanylidenepyrimidin-2-one
CAS 5254-55-7C9H11FN2O4S
1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-[(E)-prop-1-enyl]-4-sulfanyl-pyrimidin-2-one chemical structure, C12H16N2O4S, CAS 86176-91-2
1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-[(E)-prop-1-enyl]-4-sulfanyl-pyrimidin-2-one
CAS 86176-91-2C12H16N2O4S
Uridine, 2a(2)-deoxy-4-thio-, 3a(2),5a(2)-diacetate chemical structure, C13H16N2O6S, CAS 103931-23-3
Uridine, 2a(2)-deoxy-4-thio-, 3a(2),5a(2)-diacetate
CAS 103931-23-3C13H16N2O6S
(2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2-oxo-4-thioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate chemical structure, C15H18N2O8S, CAS 55003-25-3
(2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2-oxo-4-thioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate
CAS 55003-25-3C15H18N2O8S
5-Fluoro-1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl]-4-thioxo-pyrimidin-2-one chemical structure, C9H10F2N2O3S, CAS 148744-33-6
5-Fluoro-1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl]-4-thioxo-pyrimidin-2-one
CAS 148744-33-6C9H10F2N2O3S
BC6P8D2Dfx chemical structure, C9H12N2O5S, CAS 68027-44-1
BC6P8D2Dfx
CAS 68027-44-1C9H12N2O5S
5-(2-Bromoethenyl)-2'-deoxy-4-thiouridine chemical structure, C11H13BrN2O4S, CAS 554399-09-6
5-(2-Bromoethenyl)-2'-deoxy-4-thiouridine
CAS 554399-09-6C11H13BrN2O4S
2'-Deoxy-5-fluoro-4-thiouridine chemical structure, C9H11FN2O4S, CAS 724-68-5
2'-Deoxy-5-fluoro-4-thiouridine
CAS 724-68-5C9H11FN2O4S
1-(2,3-Dideoxy-2-fluoro-|A-D-threo-pentofuranosyl)-4-thiouracil chemical structure, C9H11FN2O3S, CAS 128632-07-5
1-(2,3-Dideoxy-2-fluoro-|A-D-threo-pentofuranosyl)-4-thiouracil
CAS 128632-07-5C9H11FN2O3S
4-Thiothymidine 5'-(tetrahydrogen triphosphate) chemical structure, C10H17N2O13P3S, CAS 20456-29-5
4-Thiothymidine 5'-(tetrahydrogen triphosphate)
CAS 20456-29-5C10H17N2O13P3S
4-Thiouridylic acid chemical structure, C9H13N2O8PS, CAS 4145-46-4
4-Thiouridylic acid
CAS 4145-46-4C9H13N2O8PS